Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Fibrinolysis: A Primordial System Linked to the Immune Response

Medcalf, Robert L.; Keragala, Charithani B.

(2021), INT J MOL SCI, 22(7), 3406

DOI: 10.3390/ijms22073406

The Fibrinolytic System: Mysteries and Opportunities

Medcalf, Robert L.; Keragala, Charithani B.

(2021), HemaSphere, 5(6), e570

DOI: 10.1097/HS9.0000000000000570

Platelet phenotype and function in the absence of splenic sequestration (Review)

Luu, Sarah; Woolley, Ian J.; Andrews, Robert K.

(2021), PLATELETS, 32(1), 48-53

DOI: 10.1080/09537104.2020.1732322

Global coagulation assays in healthy controls

Lim, Hui Yin; Lui, Brandon; Tacey, Mark; Selan, Carly; Donnan, Geoffrey; Burrell, Louise M.; Nandurkar, Harshal; Ho, Prahlad

(2021), J THROMB THROMBOLYS, 52(2), 610–619

DOI: 10.1007/s11239-021-02400-y

Global coagulation assays in patients with diabetes mellitus

Lim, Hui Yin; Lui, Brandon; Tacey, Mark; Kwok, Anna; Varadarajan, Suresh; Donnan, Geoffrey; Nandurkar, Harshal; Ho, Prahlad

(2021), Research and Practice in Thrombosis and Haemostasis, 5(7), e12611

DOI: 10.1002/rth2.12611

Determination of PAR4 numbers on the surface of human platelets

Li, Simeng; Tarlac, Volga; Christanto, Roberto B.I.; French, Shauna L.; Hamilton, Justin R.

(2021), PLATELETS, 32(7), 988-991

DOI: 10.1080/09537104.2020.1810654

Role of purinergic signalling in endothelial dysfunction and thrombo-inflammation in ischaemic stroke and cerebral small vessel disease

Lee, Natasha Ting; Ong, Lin Kooi; Gyawali, Prajwal; Nassir, Che Mohd Nasril Che Mohd; Mustapha, Muzaimi; Nandurkar, Harshal H.; Sashindranath, Maithili

(2021), BIOMOLECULES, 11(7), 994

DOI: 10.3390/biom11070994

Effects of water stably-enriched with oxygen as a novel method of tissue oxygenation on mitochondrial function, and as adjuvant therapy for type 2 diabetes in a randomized placebo-controlled trial

Khoo, Joan; Hagemeyer, Christoph; Henstridge, Darren C.; Kumble, Sumukh; Wang, Ting-Yi; Xu, Rong; Gani, Linsey; King, Thomas; Soh, Shui-Boon; Puar, Troy; Au, Vanessa; Tan, Eberta; Tay, Tunn Lin; Kam, Carmen; Teo, Eng-Kiong

(2021), PLOS ONE, 16(7), e0254619

DOI: 10.1371/journal.pone.0254619

Plasminogen: an enigmatic zymogen

Keragala, Charithani B.; Medcalf, Robert L.

(2021), BLOOD, 137(21), 2881-2889

DOI: 10.1182/blood.2020008951

Broad-based influenza-specific cd8+ t cell response without the typical immunodominance hierarchy and its potential implication

Huang, Miaojuan; Xu, Rong; Triffon, Cristina; Mifsud, Nicole; Chen, Weisan

(2021), VIRUSES-BASEL, 13(6), 1080

DOI: 10.3390/v13061080

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition

Hogg, Simon J.; Motorna, Olga; Cluse, Leonie A.; Johanson, Timothy M.; Coughlan, Hannah D.; Raviram, Ramya; Myers, Robert M.; Costacurta, Matteo; Todorovski, Izabela; Pijpers, Lizzy; Bjelosevic, Stefan; Williams, Tobias; Huskins, Shannon N.; Kearney, Cono

(2021), MOL CELL, 81(10), 2183-2200e13

DOI: 10.1016/j.molcel.2021.04.015

Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitro

Hoefer, Thomas; Rana, Akshita; Niego, Be'eri; Jagdale, Shweta; Albers, Hugo J.; Gardiner, Elizabeth E.; Andrews, Robert K.; van der Meer, Andries D.; Hagemeyer, Christoph e.; Westein, Erik

(2021), HAEMATOLOGICA, 106(11), 2874-2884

DOI: 10.3324/haematol.2020.250761

Chronic methamphetamine interacts with BDNF Val66Met to remodel psychosis pathways in the mesocorticolimbic proteome

Greening, David W.; Notaras, Michael; Chen, Maoshan; Xu, Rong; Smith, Joel D.; Cheng, Lesley; Simpson, Richard J.; Hill, Andrew F.; van den Buuse, Maarten

(2021), MOL PSYCHIATR, 26(8), 4431-4447

DOI: 10.1038/s41380-019-0617-8

Deletion of IKK2 in haematopoietic cells of adult mice leads to elevated interleukin-6, neutrophilia and fatal gastrointestinal inflammation

Fischer, Karla C.; Daunt, Carmel P.; Tremblay, Cédric S.; Dias, Sheila; Vince, James E.; Jabbour, Anissa M.

(2021), CELL DEATH DIS, 12(1), 28

DOI: 10.1038/s41419-020-03298-9

Collagen-targeted peptides for molecular imaging of diffuse cardiac fibrosis

Ezeani, Martin; Noor, Asif; Alt, Karen; Lal, Sean; Donnelly, Paul S.; Hagemeyer, Christoph E.; Niego, Be’Eri

(2021), J AM HEART ASSOC, 10(18), e022139

DOI: 10.1161/JAHA.121.022139

Important factors in implementation of lineage-specific chimerism analysis for routine use

Das, Tongted P.; Kipp, David A.; Kliman, David S.; Patil, Sushrut S.; Curtis, David J.; O’Brien, Maureen E.; Swain, Michael I.; Widjaja, Jacqueline M.L.; Cooke, Jade L.; Ziino, Melinda N.; Spencer, Andrew

(2021), BONE MARROW TRANSPL, 56(4), 946-948

DOI: 10.1038/s41409-020-01089-6

CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation

Chüeh, Anderly C.; Advani, Gahana; Foroutan, Momeneh; Smith, Jai; Ng, Nadia; Nandurkar, Harshal; Lio, Daisy S.; Zhu, Hong Jian; Chong, Yuh Ping; Verkade, Heather; Fujita, Donald J.; Bjorge, Jeffrey; Basheer, Faiza; Lim, Jet Phey; Luk, Ian; Dhillon, Amarde

(2021), ONCOGENE, 40, 3015-3029

DOI: 10.1038/s41388-021-01755-z

The Patients’ Perspective: Hematological Cancer Patients' Experiences of Adverse Events as Part of Care

Bryant, Jamie; Carey, Mariko; Sanson-Fisher, Rob; Turon, Heidi; Wei, Andrew; Kuss, Bryone

(2021), J PATIENT SAF, 17(5), e387-e392

DOI: 10.1097/PTS.0000000000000347

Serine Biosynthesis Is a Metabolic Vulnerability in FLT3-ITD-Driven Acute Myeloid Leukemia

Bjelosevic, Stefan; Gruber, Emily; Newbold, Andrea; Shembrey, Carolyn; Devlin, Jennifer R.; Hogg, Simon J.; Kats, Lev; Todorovski, Izabela; Fan, Zheng; Abrehart, Thomas C.; Pomilio, Giovanna; Wei, Andrew; Gregory, Gareth P.; Vervoort, Stephin J.; Brown, K

(2021), CANCER DISCOV, 11(6), 1582-1599

DOI: 10.1158/2159-8290.CD-20-0738

Blood apheresis technologies-a critical review on challenges towards efficient blood separation and treatment

Bacal, Christine Jurene O.; Maina, James W.; Nandurkar, Harshal H.; Khaleel, Maryam; Guijt, Rosanne; Chang, Yung; Dwyer, Karen M.; Dumée, Ludovic F.

(2021), Materials Advances, 2(22), 7210-7236

DOI: 10.1039/d1ma00859e

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