Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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T-ALL can evolve to oncogene independence

Abdulla, Hesham; Vo, Anh; Shields, Benjamin J.; Davies, Tenae J.; Jackson, Jacob T.; Alserihi, Raed; Viney, Elizabeth M.; Wong, Tin; Yan, Feng; Wong, Nicholas C.; Demoen, Lisa; Curtis, David J.; Alexander, Warren S.; Van Vlierberghe, Pieter; Dickins, Ross

(2021), LEUKEMIA, 35, 2205–2219

DOI: 10.1038/s41375-021-01120-9

AAA stewardship: managing high-risk medications with dedicated antimicrobial, anticoagulation and analgesic stewardship programs

Thuy Bui, Hadley Bortz, Kelly Cairns, Linda Graudins, Carmela Corallo, Alex Konstantatos, Huyen Tran, Allen Cheng, Michael Dooley

(2021), Journal of Pharmacy Practice and Research, 51(4), 342-7

DOI: 10.1002/jppr.1716

Real-World Rates of Bleeding, Factor VIII Use, and Quality of Life in Individuals with Severe Haemophilia A Receiving Prophylaxis in a Prospective, Non-Interventional Study

Kenet G, Chen YC, Lowe G, Percy C, Tran H, von Drygalski A, Trossaërt M, Reding M, Oldenburg J, Mingot-Castellano ME, Park YS, Peyvandi F, Ozelo MC, Mahlangu J, Quinn J, Huang M, Reddy DB, Kim B

(2021), J Clin Med, 10(24), 5959

DOI: 10.3390/jcm10245959

Australian and New Zealand approach to diagnosis and management of vaccine-induced thrombosis and thrombocytopenia

Chen VM, Curnow JL, Tran HA, Choi PY

(2021), MED J AUSTRALIA, 215(6), 245-9.e1

DOI: 10.5694/mja2.51229

Tranexamic acid rapidly inhibits fibrinolysis, yet transiently enhances plasmin generation in vivo

Draxler DF, Zahra S, Goncalves I, Tran H, Hanafi G, Ho H, Keragala CB, Ilich A, Key NS, Myles PS, Medcalf RL

(2021), BLOOD COAGUL FIBRIN, 32(3), 172-9

DOI: 10.1097/MBC.0000000000001008

Acquired haemophilia and haemostatic control with recombinant porcine factor VIII: case series

Campbell S, Mason J, Prasad R, Ambrose H, Hunt S, Tran H

(2021), Intern Med J, 51(2), 215-9

DOI: 10.1111/imj.14773

The first known case of vaccine-induced thrombotic thrombocytopenia in Australia

Hocking J, Chunilal SD, Chen VM, Brighton T, Nguyen J, Tan J, Ting SB, Tran H

(2021), MED J AUSTRALIA, 215(1), 19-20e.1

DOI: 10.5694/mja2.51135

Upper extremity deep vein thrombosis: current knowledge and future directions

Yuen HLA, Tran H, Chunilal S

(2021), Semin Thromb Hemost, 47(6), 677-91

DOI: 10.1055/s-0041-1725116

Cereblon pathway biomarkers and immune profiles in patients receiving post-ASCT lenalidomide maintenance (LEOPARD)

Kalff A, Khong T, Ramachandran M, Walker P, Schwarer A, Roberts AW, Campbell P, Filshie R, Norton S, Reynolds J, Young M, Pierceall W, Thakurta A, Guo M, Oppermann U, Wang M, Ren Y, Kennedy N, Parekh S, Spencer A

(2021), LEUKEMIA LYMPHOMA, 62(21), 2981-91

DOI: 10.1080/10428194.2021.1948030

A phase II trial of continuous ixazomib, thalidomide and dexamethasone for relapsed and/or refractory multiple myeloma: the Australasian Myeloma Research Consortium (AMaRC) 16-02 trial

Bergin K, Yuen F, Wallington-Beddoe C, Kalff A, Sirdesai S, Reynolds J, Spencer A

(2021), BRIT J HAEMATOL, 194(3), 580-6

DOI: 10.1111/bjh.17504

Clinical impact of NPM1-mutant molecular persistence after chemotherapy for acute myeloid leukemia

Tiong IS, Dillon R, Ivey A, Kuzich JA, Thiagarajah N, Sharplin KM, Kok CH, Tedjaseputra A, Rowland JP, Grove CS, Abro E, Shortt J, Hiwase DK, Bajel A, Potter NE, Smith ML, Hemmaway CJ, Thomas A, Gilkes AF, Russell NH, Wei AH

(2021), Blood Adv, 5(23), 5107-111

DOI: 10.1182/bloodadvances.2021005455

Phase II trial of single-agent panobinostat consolidation improves responses after sub-optimal transplant outcomes in multiple myeloma

Mithraprabhu S, Kalff A, Gartlan KH, Savvidou I, Khong T, Ramachandran M, Cooke RE, Bowen K, Hill GR, Reynolds J, Spencer A

(2021), BRIT J HAEMATOL, 193(1), 160-70

DOI: 10.1111/bjh.17080

Recent advances in molecular imaging of atherosclerotic plaques and thrombosis

Qiao, Ruirui; Huang, Xumin; Qin, Yu; Li, Yuhuan; Davis, Thomas P.; Hagemeyer, Christoph E.; Gao, Mingyuan

(2020), NANOSCALE, 12(15), 8040-8064.

DOI: 10.1039/d0nr00599a

Functionalization of NaGdF4 nanoparticles with a dibromomaleimide-terminated polymer for MR/optical imaging of thrombosis

Li, Yuhuan; Xin, Fangyun; Hu, Jinming; Jagdale, Shweta; Davis, Thomas P.; Hagemeyer, Christoph E.; Qiao, Ruirui

(2020), POLYM CHEM-UK, 11(5), 1010-1017.

DOI: 10.1039/c9py01568j

Cobalt-Directed Assembly of Antibodies onto Metal-Phenolic Networks for Enhanced Particle Targeting

Zhang, Wenjie; Besford, Quinn A.; Christofferson, Andrew J.; Charchar, Patrick; Richardson, Joseph J.; Elbourne, Aaron; Kempe, Kristian; Hagemeyer, Christoph E.; Field, Matthew R.; Mcconville, Chris F.; Yarovsky, Irene; Caruso, Frank

(2020), NANO LETT, 20(4), 2660-2666.

DOI: 10.1021/acs.nanolett.0c00295

Risk Stratification of Acute Pulmonary Embolism and Determining the Effect on Chronic Cardiopulmonary Complications: The REACH Study

Stevens H, Fang W, Clements W, Bloom J, McFadyen J, Tran H

(2020), TH Open, 40(1), e45-50

DOI: 10.1055/s-0040-1708558

Predicting the Risk of Recurrent Venous Thromboembolism: Current Challenges and Future Opportunities

Stevens H, Peter K, Tran H, McFadyen J

(2020), J Clin Med, 9(5), 1582

DOI: 10.3390/jcm9051582

Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface

Awad, Milena M.; Hutton, Melanie L.; Quek, Adam J.; Klare, William P.; Mileto, Steven J.; Mackin, Kate; Ly, Diane; Oorschot, Viola; Bosnjak, Marijana; Jenkin, Grant; Conroy, Paul J.; West, Nick; Fulcher, Alex; Costin, Adam; Day, Christopher J.; Jennings,

(2020), GASTROENTEROLOGY, 159(4), 1431-1443.e6.

DOI: 10.1053/j.gastro.2020.06.032

TINC— A Method to Dissect Regulatory Complexes at Single-Locus Resolution— Reveals an Extensive Protein Complex at the Nanog Promoter

Knaupp, Anja S.; Mohenska, Monika; Larcombe, Michael R.; Ford, Ethan; Lim, Sue Mei; Wong, Kayla; Chen, Joseph; Firas, Jaber; Huang, Cheng; Liu, Xiaodong; Nguyen, Trung; Sun, Yu B.Y.; Holmes, Melissa L.; Tripathi, Pratibha; Pflueger, Jahnvi; Rossello, Fern

(2020), STEM CELL REP, 15(6), 1246-1259.

DOI: 10.1016/j.stemcr.2020.11.005

Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance

Goh, Wilford; Scheer, Sebastian; Jackson, Jacob T.; Hediyeh-Zadeh, Soroor; Delconte, Rebecca B.; Schuster, Iona S.; Andoniou, Christopher E.; Rautela, Jai; Degli-Esposti, Mariapia A.; Davis, Melissa J.; McCormack, Matthew P.; Nutt, Stephen L.; Huntington,

(2020), CELL REP, 33(3), 108285

DOI: 10.1016/j.celrep.2020.108285