Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Age, sex and racial differences in fibrin formation and fibrinolysis within the healthy population

Wang, Julie; Lim, Hui Y; Nandurkar, Harshal; Ho, Prahlad

(2022), BLOOD COAGUL FIBRIN, 33(2), 141-144

DOI: 10.1097/MBC.0000000000001115

The Potential Role of Protease Systems in Hemophilic Arthropathy

Hauw, Wei Say Wayne; Chia, Joanne SJ; Nandurkar, Harshal H; Sashindranath, Maithili

(2022), BLOOD ADV, 6(18), 5505-5515

DOI: 10.1182/bloodadvances.2022007028

A novel flow cytometry procoagulant assay for diagnosis of vaccine-induced immune thrombotic thrombocytopenia

Lee, Christine SM; Liang, Hai Po Helena; Connor, David E; Dey, Agnibesh; Tohidi-Esfahani, Ibrahim; Campbell, Heather; Whittaker, Shane; Capraro, David; Favaloro, Emmanuel J; Donikian, Dea; Kondo, Mayuko; Hicks, Sarah M; Choi, Philip YI; Gardiner, E

(2022), BLOOD ADV, 6(11), 3494-3506

DOI: 10.1182/bloodadvances.2021006698

Neutrophil cathepsin G proteolysis of protease-activated receptor 4 generates a novel, functional tethered ligand

Stoller, Michelle L; Basak, Indranil; Denorme, Frederik; Rowley, Jesse W; Alsobrooks, James; Parsawar, Krishna; Nieman, Marvin T; Yost, Christian Con; Hamilton, Justin R; Bray, Paul F; Campbell, Robert A

(2022), BLOOD ADV, 6(7), 2303-2308

DOI: 10.1182/bloodadvances.2021006133

Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis

de Maat, Steven; Clark, Chantal C; Barendrecht, Arjan D; Smits, Simone; van Kleef, Nadine D; El Otmani, Hinde; Waning, Manon; van Moorsel, Marc; Szardenings, Michael; Delaroque, Nicolas; Vercruysse, Kristof; Urbanus, Rolf T; Sebastian, Silvie; Lenting

(2022), BLOOD, 139(4), 597-607

DOI: 10.1182/blood.2021011776

Self-Assembly of Oriented Antibody-Decorated Metal–Organic Framework Nanocrystals for Active-Targeting Applications

Alt, Karen; Carraro, Francesco; Jap, Edwina; Linares-Moreau, Mercedes; Riccò, Raffaele; Righetto, Marcello; Bogar, Marco; Amenitsch, Heinz; Hashad, Rania A; Doonan, Christian; Hagemeyer, Christoph E; Falcaro, Paolo

(2022), ADV MATER, 34(21), 2106607

DOI: 10.1002/adma.202106607

Polyphenol-Functionalized Cubosomes as Thrombolytic Drug Carriers

Yu, Haitao; Palazzolo, Jason S; Ju, Yi; Niego, Be'eri; Pan, Shuaijun; Hagemeyer, Christoph E; Caruso, Frank

(2022), ADV HEALTHC MATER, 11(21), 2201151

DOI: 10.1002/adhm.202201151

Alcohol use in the year following approach bias modification during inpatient withdrawal: secondary outcomes from a double-blind, multi-site randomized controlled trial

Manning, Victoria; Garfield, Joshua BB; Reynolds, John; Staiger, Petra K; Piercy, Hugh; Bonomo, Yvonne; Lloyd-Jones, Martyn; Jacka, David; Wiers, Reinout W; Verdejo-Garcia, Antonio; Lubman, Dan I

(2022), ADDICTION, 117(11), 2837-2846

DOI: 10.1111/add.15989

Bioresponsive Polyphenol-Based Nanoparticles as Thrombolytic Drug Carriers

Yu, Haitao; Palazzolo, Jason S; Zhou, Jiajing; Hu, Yingjie; Niego, Be'Eri; Pan, Shuaijun; Ju, Yi; Wang, Ting Yi; Lin, Zhixing; Hagemeyer, Christoph E; Caruso, Frank

(2022), ACS APPL MATER INTER, 14(3), 3740-3751

DOI: 10.1021/acsami.1c19820

Pulmonary embolus

Dix, Caroline; Tran, Huyen

(2022), AUST J GEN PRACT, 51(9), 667-671

DOI: 10.31128/AJGP-05-22-6440

Identification of a Distinct Platelet Phenotype in the Elderly: ADP Hypersensitivity Coexists With Platelet PAR (Protease-Activated Receptor)-1 and PAR-4-Mediated Thrombin Resistance

Gnanenthiran, Sonali R; Pennings, Gabrielle J; Reddel, Caroline J; Campbell, Heather; Kockx, Maaike; Hamilton, Justin R; Chen, Vivien M; Kritharides, Leonard

(2022), ARTERIOSCL THROM VAS, 42(8), 960-972

DOI: 10.1161/ATVBAHA.120.316772

Tranexamic acid alters the immunophenotype of phagocytes after lower limb surgery

Draxler DF, Hanafi G, Zahra S, McCutcheon F, Ho H, Keragala CB, Liu Z, Daly D, Painter T, Wallace S, Plebanski M, Myles PS, Medcalf RL

(2022), Thromb J, 20(1), 17

DOI: 10.1186/s12959-022-00373-3

Characterisation of Plasma Mitochondrial DNA, MMP-9 and Neutrophil Elastase in Patients Undergoing Coronary Artery Bypass Grafting: Effects of Tranexamic Acid and Postoperative Pneumonia

Sandler N, Ho H, Draxler DF, Bain CR, Smith JA, Hauser CJ, Gruen RL, Myles PS, Medcalf RL

(2022), Heart Lung Circ, 31(3), 439-46

DOI: 10.1016/j.hlc.2021.08.008

Palifermin, administered for three doses only, reduces mucositis in patients undergoing HSCT and receiving chemoradiotherapy conditioning

Coutsouvelis J, Dooley M, Kirkpatrick CM, Avery S, Hopkins R, Spencer A

(2022), BONE MARROW TRANSPL, 57(8), 1329-31

DOI: 10.1038/s41409-022-01714-6

Receiving four or fewer cycles of therapy predicts poor survival in newly diagnosed transplant-ineligible patients with myeloma who are treated with bortezomib-based induction

Boyle, Stephen; Wellard, Cameron; Moore, Elizabeth M.; Blacklock, Hilary; Harrison, Simon J.; Ho, Phoebe Joy; Hocking, Jay; McQuilten, Zoe K.; Quach, Hang; Spearing, Ruth; Wood, Erica M.; Spencer, Andrew; Mollee, Peter; ,

(2021), EUR J HAEMATOL, 107(4), 497-499

DOI: 10.1111/ejh.13677

TOP2A expression predicts responsiveness to carfilzomib in myeloma and informs novel combinatorial strategies for enhanced proteasome inhibitor cell killing

Reale, Antonia; Khong, Tiffany; Mithraprabhu, Sridurga; Savvidou, Ioanna; Hocking, Jay John; Bergin, Krystal Frances; Ramachandran, Malarmathy; Chen, Maoshan; Dammacco, Francesco; Ria, Roberto; Silvestris, Francesco; Vacca, Angelo; Reynolds, John; Spencer

(2021), LEUKEMIA LYMPHOMA, 62(2), 337-347

DOI: 10.1080/10428194.2020.1832659

Estimating the Productivity Impact of Acute Myeloid Leukemia in Australia Between 2020 and 2029, Using a Novel Work Utility Measure

Parker, Catriona; Liew, Danny; Ademi, Zanfina; Owen, Alice; Ayton, Darshini R; Wei, Andrew H.; Zomer, Ella

(2021), JCO ONCOL PRACT, 17(11), E1803-E1810

DOI: 10.1200/OP.20.00904

The Myeloma Landscape in Australia and New Zealand: The First 8 Years of the Myeloma and Related Diseases Registry (MRDR)

Bergin, Krystal; Wellard, Cameron; Moore, Elizabeth; McQuilten, Zoe; Blacklock, Hilary; Harrison, Simon J.; Ho, P. Joy; King, Tracy; Quach, Hang; Mollee, Peter; Walker, Patricia; Wood, Erica; Spencer, Andrew; ,

(2021), CL LYMPH MYELOM LEUK, 21(6), e510-e520

DOI: 10.1016/j.clml.2021.01.016

Real-world utilisation of ASCT in multiple myeloma (MM)

Bergin, Krystal; Wellard, Cameron; Augustson, Bradley; Cooke, Rachel; Blacklock, Hilary; Harrison, Simon J.; Ho, Joy; King, Tracy; Quach, Hang; Mollee, Peter; Walker, Patricia; Moore, Elizabeth; McQuilten, Zoe; Wood, Erica; Spencer, Andrew; ,

(2021), BONE MARROW TRANSPL, 56(10), 2533-2543

DOI: 10.1038/s41409-021-01308-8

Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine

Yeola, Avani; Subramanian, Shruthi; Oliver, Rema A.; Lucas, Christine A.; Thoms, Julie A.I.; Yan, Feng; Olivier, Jake; Chacon, Diego; Tursky, Melinda L.; Srivastava, Pallavi; Potas, Jason R.; Hung, Tzongtyng; Power, Carl; Hardy, Philip; Ma, David D.; Kili

(2021), SCI ADV, 7(3), eabd1929

DOI: 10.1126/sciadv.abd1929