Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Fitness criteria for Australian patients referred for chimeric antigen receptor T-cell therapy

Tam, Constantine S; Ho, P J; Purtill, Duncan; Blyth, Emily; Butler, Jason; Dickinson, Michael; Harrison, Simon

(2022), INTERN MED J, 52(8), 1454-1456

DOI: 10.1111/imj.15868

Isolated distal DVT in trauma: A study of the management of isolated distal deep vein thrombosis acquired as an inpatient in trauma patients

Day, Thomas; Tran, Huyen; Chunilal, Sanjeev; Bortz, Hadley; Esterman, Adrian

(2022), INJURY, 53(7), 2562-2566

DOI: 10.1016/j.injury.2022.01.026

Oral Anticoagulant Use in Patients With Atrial Fibrillation and Chronic Kidney Disease: A Review of the Evidence With Recommendations for Australian Clinical Practice

Hammett, Christopher; Badve, Sunil V; Kerr, Peter G; Tran, Huyen A; Dundon, Benjamin K; Lo, Sidney; Wong, Andrew; Joseph, Joanne E; Deague, Jenny; Perkovic, Vlado

(2022), HEART LUNG CIRC, 31(12), 1604-1611

DOI: 10.1016/j.hlc.2022.09.003

Acquired haemophilia A: Insight into treatment and outcomes from an Australian tertiary referral centre

Dix, Caroline; Tee, Amanda; McFadyen, James D; Tran, Huyen

(2022), HAEMOPHILIA, 28(2), e49-e52

DOI: 10.1111/hae.14481

Osteoporosis management and falls prevention in patients with haemophilia

Petkovic, Madison J; Tran, Huyen A; Ebeling, Peter R; Zengin, Ayse

(2022), HAEMOPHILIA, 28(3), 388-396

DOI: 10.1111/hae.14540

FLT3-ITD signals bad news for core binding factor acute myeloid leukemia unless trisomy 22 comes to the rescue

Loo, Sun; Wei, Andrew H

(2022), HAEMATOLOGICA, 107(4), 783-784

DOI: 10.3324/haematol.2021.279409

Planned withdrawal of dexamethasone after pomalidomide low-dose dexamethasone induction for lenalidomide-refractory multiple myeloma (ALLG MM14)

Kalff, Anna; Khong, Tiffany; Ramachandran, Malarmathy; Joy Ho, P; Mollee, Peter; D’Rozario, James; Taylor, Kerry; Estell, Jane; Norton, Sam; Kemp, Roslyn; Mitchell, Andrew J; Reynolds, John; Kennedy, Nola; Quach, Hang; Spencer, Andrew

(2022), HAEMATOLOGICA, 107(1), 321-325

DOI: 10.3324/haematol.2021.278655

Idiopathic upper extremity deep vein thrombosis: A systematic review

Yuen, Hiu Lam Agnes; Tan, Ee; Tran, Huyen; Chunilal, Sanjeev Daya

(2022), EUR J HAEMATOL, 109(5), 542-558

DOI: 10.1111/ejh.13842

Inhibition of pyrimidine biosynthesis targets protein translation in acute myeloid leukemia

So, Joan; Lewis, Alexander C; Smith, Lorey K; Stanley, Kym; Franich, Rheana; Yoannidis, David; Pijpers, Lizzy; Dominguez, Pilar; Hogg, Simon J; Vervoort, Stephin J; Brown, Fiona C; Johnstone, Ricky W; McDonald, Gabrielle; Ulanet, Danielle B; Murtie

(2022), EMBO MOL MED, 14(7), e15203

DOI: 10.15252/emmm.202115203

Mopping up crystals to keep the blood flowing

Hagemeyer, Christoph E

(2022), EBIOMEDICINE, 75, 103786

DOI: 10.1016/j.ebiom.2021.103786

Overall Hemostatic Potential Assay Detects Risk of Progression to Post-Thrombotic Syndrome in Anticoagulated Patients following Deep Vein Thrombosis

McLeod, Blake; Lim, Hui Yin; Nandurkar, Harshal; Ho, Prahlad; Wang, Julie

(2022), DIAGNOSTICS, 12(12), 3165

DOI: 10.3390/diagnostics12123165

SOHO State of the Art Updates and Next Questions | Mechanisms of Resistance to BCL2 Inhibitor Therapy in Chronic Lymphocytic Leukemia and Potential Future Therapeutic Directions

Bennett, Rory; Thompson, Ella; Tam, Constantine

(2022), CL LYMPH MYELOM LEUK, 22(11), 795-804

DOI: 10.1016/j.clml.2022.07.013

Template-Assisted Antibody Assembly: A Versatile Approach for Engineering Functional Antibody Nanoparticles

Hu, Yingjie; Li, Jianhua; Ju, Yi; Houston, Zachary H; Fletcher, Nicholas L; De Rose, Robert; Fernandes, Soraia; Hagemeyer, Christoph E; Alt, Karen; Thurecht, Kristofer J; Cortez-Jugo, Christina; Caruso, Frank

(2022), CHEM MATER, 34(8), 3694-3704

DOI: 10.1021/acs.chemmater.1c04397

Combination of Histone Deacetylase Inhibitor Panobinostat (LBH589) with ß-Catenin Inhibitor Tegavivint (BC2059) Exerts Significant Anti-Myeloma Activity Both In Vitro and In Vivo

Savvidou, Ioanna; Khong, Tiffany; Whish, Sophie; Carmichael, Irena; Sepehrizadeh, Tara; Mithraprabhu, Sridurga; Horrigan, Stephen K; de Veer, Michael; Spencer, Andrew

(2022), CANCERS, 14(3), 840

DOI: 10.3390/cancers14030840

Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death

Garciaz, Sylvain; Guirguis, Andrew A; Müller, Sebastian; Brown, Fiona C; Chan, Yih-Chih; Motazedian, Ali; Rowe, Caitlin L; Kuzich, James A; Chan, Kah Lok; Tran, Kevin; Smith, Lorey; MacPherson, Laura; Liddicoat, Brian; Lam, Enid YN; Cañeque, Tatiana

(2022), CANCER DISCOV, 12(3), 774-791

DOI: 10.1158/2159-8290.CD-21-0522

Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

Salmon, Jessica M; Todorovski, Izabela; Stanley, Kym L; Bruedigam, Claudia; Kearney, Conor J; Martelotto, Luciano G; Rossello, Fernando; Semple, Timothy; Arnau, Gisela Mir; Zethoven, Magnus; Bots, Michael; Bjelosevic, Stefan; Cluse, Leonie A; Fraser,

(2022), CANCER DISCOV, 12(6), 1560-1579

DOI: 10.1158/2159-8290.CD-20-1145

Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses

Chan, Kah Lok; Gomez, Juliana; Cardinez, Chelisa; Kumari, Nishi; Sparbier, Christina E; Lam, Enid YN; Yeung, Miriam M; Garciaz, Sylvain; Kuzich, James A; Ong, Doen Ming; Brown, Fiona C; Chan, Yih-Chih; Vassiliadis, Dane; Wainwright, Elanor N; Motaz

(2022), CANCER CELL, 40(10), 1190-1206e9

DOI: 10.1016/j.ccell.2022.09.007

Ibrutinib use, treatment duration, and concomitant medications in Australian patients with relapsed or refractory chronic lymphocytic leukaemia

Mulligan, Stephen P; Opat, Stephen; Marlton, Paula; Kuss, Bryone; Gerungan, Poppy; Puig, Andrea; McGeachie, Marija; Tam, Constantine S

(2022), BRIT J HAEMATOL, 198(4), 790-793

DOI: 10.1111/bjh.18306

An extensional strain sensing mechanosome drives adhesion-independent platelet activation at supraphysiological hemodynamic gradients

Zainal Abidin, Nurul A; Poon, Eric KW; Szydzik, Crispin; Timofeeva, Mariia; Akbaridoust, Farzan; Brazilek, Rose J; Tovar Lopez, Francisco J; Ma, Xiao; Lav, Chitrarth; Marusic, Ivan; Thompson, Philip E; Mitchell, Arnan; Ooi, Andrew SH; Hamilton, Ju

(2022), BMC BIOL, 20(1), 73

DOI: 10.1186/s12915-022-01274-7

A novel ex vivo approach for measuring plasminogen activation upon established plasma clots

Palazzolo, Jason S; Medcalf, Robert L; Hagemeyer, Christoph E; Niego, Be'eri

(2022), RES PRACT THROMB HAE, 6(5)

DOI: 10.1002/rth2.12771

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