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Our clinical trial portfolio is one of the largest in the country. We have more than 700 clinical trials open across 30 clinical units.

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604 clinical trials found
Clinical trials

MEGA-ROX

The Mega Randomised Registry Trial Comparing Conservative vs.Liberal OXygenation Targets (Mega-ROX) (ACTRN12620000391976)

No longer recruiting

MEMENTO

MEMENTO - A Phase 4, Single-arm, Open-label Clinical Study to Evaluate Mavacamten in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy to Assess the Impact on Myocardial Structure with Cardiac Magnetic Resonance Imaging [CMR] (NCT06112743)

Currently recruiting

MHT vs SSRI

A randomised double-blinded interventional trial of estradiol and zoloft to treat menopausal depression (ACTRN12624000475549p)

Currently recruiting

MIDAS 2

A Phase III, Multicentre, Prospective, Randomised, Placebo-controlled, Double-blind, Parallel group, with an adaptive sample size re-estimation study in Stroke Survivors (ACTRN12618000602224)

Currently recruiting

MIST

A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study Evaluating the Safety and Efficacy of Pirfenidone Solution for Inhalation [AP01] in Subjects with Progressive Pulmonary Fibrosis [PPF] (NCT06329401)

Currently recruiting

MK-0482-001

A Phase 1b, Open-Label, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MK-0482 as Monotherapy and in Combination with Pembrolizumab in Participants with Advanced/Metastatic Solid Tumors. (NCT03918278)

No longer recruiting

MK-1022-011

A Phase 1/2 Study to Evaluate the Safety and Efficacy of Patritumab Deruxtecan in Gastrointestinal Cancers (NCT06596694)

Currently recruiting

MK-1200-002

A Phase 1/2 Open-label Study to Evaluate the Safety and Efficacy of MK-1200 in Participants with Advanced Solid Tumors (NCT06242691)

No longer recruiting

MK-4280A-010

A Multicenter, Randomized, Double-Blind, Phase 2, Basket Study of MK-4280A, a Coformulation of Favezelimab (MK-4280) with Pembrolizumab (MK-3475) in Selected Solid Tumors (NCT06036836)

No longer recruiting

MK-6837

A Phase 1 Open-label, Multicenter Study of MK-6837 as Monotherapy and Combination Therapy in Participants with Advanced/Metastatic Solid Tumors (NCT06460961)

Currently recruiting

MK-8591B 060

Phase 2 Study of ISL+ULO QW in Virologically Suppressed Adults With HIV-1 (NCT06891066)

Currently recruiting

MK7240-012

A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Tulisokibart in Participants with Moderate to Severe Hidradenitis Suppurativa (NCT06956235)

This is a phase 2b randomized, double-blind, placebo-controlled study of the safety and efficacy of tulisokibart in participants with moderate to severe hidradenitis suppurativa. This study consists of a 16-week Double-blind Period and a 100-week Longterm Extension (LTE) composed of a 40-week Main Extension and a 60-week Optional Extension. Each participant will participate in the study for approximately 135 weeks from the time the participant provides documented informed consent through the final contact. (including screening & follow up). There will be 147 participants across 70 centers worldwide.
No longer recruiting

MKC-CI-002

ICoN-1: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101 [Clofazimine Inhalation Suspension] When Added to Guideline-Based Therapy in Participants with Pulmonary Nontuberculous Mycobacterial Infection [Part A] Followed by an Open-Label Extension [Part B] (NCT06418711).

This clinical trial is designed to compare the efficacy and safety of Clofazimine Inhalation Suspension versus placebo when added to guideline-based therapy (GBT).
Currently recruiting

MND-PLL001

A Multi-centre, Phase 1/2, Randomised, Double-blind, Placebo-controlled Study with an Optional Open-label Extension to Evaluate the Safety, Tolerability, Efficacy, and Pharmacodynamics of PLL001 for the Treatment of Subjects with Amyotrophic Lateral Sclerosis (NCT06513546)

Currently recruiting

MOG001

A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 3, Pivotal Study With an Open-Label Extension Period to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-Associated Disease (MOG-AD) (NCT05063162)

Currently recruiting

MonumenTAL-2

A Multi-arm Phase 1b Study of Talquetamab With Other Anticancer Therapies in Participants with Multiple Myeloma (NCT05050097)

Currently recruiting

MonumenTAL-8

A Phase 2, Open-Label, Multicenter Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants with High-Risk Multiple Myeloma (MonumenTAL-8) (NCT06550895)

Currently recruiting

MRDRIVE-ALL

MRDRIVE-ALL: Minimal Residual Disease Driven Intervention in Elderly Acute Lymphoblastic Leukaemia (Trial Not Registered)

Currently recruiting

mRNA-2752

A Phase 1, Open-Label, Multicenter, Dose Escalation Study of mRNA-2752, a Lipid Nanoparticle Encapsulating mRNAs Encoding Human OX40L, IL-23, and IL-36, for Intratumoral Injection Alone and in Combination with Immune Checkpoint Blockade (NCT03739931)

No longer recruiting

MRTLE-DB

A Phase 2, Double-Blind, Randomized, Placebo-Controlled Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 via an Implantable Pump and a Cranial Port and Double Lumen Catheter (CIC) in Subjects with Focal Seizures, with Temporal Lobe Onset with or without Secondary Generalization (NCT04153175)

Currently recruiting
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