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Our clinical trial portfolio is one of the largest in the country. We have more than 700 clinical trials open across 30 clinical units.

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599 clinical trials found

Clinical trials

M23-324

Study M23-324: A First-in-Human Study of ABBV-525 (MALT1 Inhibitor) in B-Cell Malignancies (NCT05618028)

Currently recruiting

M23-698

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Efficacy and Safety of Upadacitinib in Adult and Adolescent Subjects with Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy (NCT05889182)

The M23-698 trial is a study designed to evaluate the safety and efficacy of a potential new medication compared to placebo in reducing symptoms and improving the quality of life for participants living with Hidradenitis Supparativa (HS). Participants receive either trial medication or a placebo (something that looks like the trial drug but has no effect on the body), both administered as oral treatments. The study will involve 19 study visits over the course of approximately two years.

Currently recruiting

MAD-NOCA

Multivessel compared to Single Vessel Functional Angiography to Diagnose Patients with No Obstructive Coronary Artery Disease: The MAD-NOCA trial (ACTRN12622001521718)

Currently recruiting

MAESTRO-NASH

A Phase 3, Multinational, Double-Blind, Randomized, Placebo-Controlled Study of MGL-3196 (resmetirom) in Patients With Non-Alcoholic Steatohepatitis (NASH) and Fibrosis to Resolve NASH and Reduce Progression to Cirrhosis and/or Hepatic Decompensation (NCT03900429)

Currently recruiting

MAGIK

Using implanted markers to determine the feasibility of Markerless Image Guidance using Intrafraction Kilovoltage X-ray Imaging: A Phase I Interventional Study of Lung Cancer Radiotherapy (NCT04086082)

Currently recruiting

MagnetisMM-6

AN OPEN-LABEL, 2-ARM, MULTICENTER, RANDOMIZED PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ELRANATAMAB (PF-06863135) + DARATUMUMAB + LENALIDOMIDE VERSUS DARATUMUMAB + LENALIDOMIDE + DEXAMETHASONE IN TRANSPLANT-INELIGIBLE PARTICIPANTS WITH NEWLY-DIAGNOSED MULTIPLE MYELOMA [C1071006] (NCT05623020)

Currently recruiting

Magnitude Study

MAGNITUDE: A Phase 3, Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of NTLA-2001 in Participants with Transthyretin Amyloidosis with Cardiomyopathy [ATTR-CM] (NCT06128629)

Currently recruiting

MajesTEC-2

A Multicentre, multi-arm, non-randomised, Phase 1b dose escalation Study of Teclistamab for newly diagnosed or relapsed/refractory MM. (NCT03145181)

No longer recruiting

MajesTEC-4

Phase 3 Study of Teclistamab in Combination with Lenalidomide versus Lenalidomide Alone in Participants with Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation (MajesTEC-4) (NCT05243797)

Currently recruiting

MANTA

Percutaneous Decannulation of Extracorporeal Membrane Oxygenation Using MANTA Vascular Closure Device (ACTRN12621000791831)

Currently recruiting

MARINUS SE [RAISE]

A double-blind, randomized, placebo-controlled study to evaluate the efficacy and safety of intravenous ganaxolone in status epilepticus (NCT04391569)

Currently recruiting

MARINUS TSC [TRUSTTSC]-DB

A Phase 3, Double-blind, Randomized, Placebo-controlled Trial of Adjunctive Ganaxolone (GNX) Treatment in Children and Adults with Tuberous Sclerosis Complex (TSC)-related Epilepsy (TrustTSC) (NCT05323734)

Currently recruiting

MarkV-01

A Phase 1a/1b, First-in-Human, Open Label Study to Assess the Safety, Tolerability, and Pharmacokinetics of PMC-309 (Anti-VISTA), as Monotherapy and Combined With Pembrolizumab, in Patients With Advanced or Metastatic Solid Tumors (NCT05957081)

Currently recruiting

MASTERPLAN

MASTERPLAN: A randomised phase II study of MFOLFIRINOX And Stereotactic Radiotherapy (SBRT) for Pancreatic Cancer With High Risk and Locally Advanced Disease (NCT04089150)

No longer recruiting

MAT

The Metformin Aneurysm Trial (MAT) (ACTRN12618001707257)

Currently recruiting

MCLA-158-CL03

A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Recurrent or Metastatic PD-L1+ Head and Neck Squamous Cell Carcinoma [LiGeR-HN1)

Phase 3 randomized, open-label study to evaluate the efficacy and safety of petosemtamab plus pembrolizumab vs pembrolizumab in first-line treatment of recurrent or metastatic PD-L1+ head and neck squamous cell carcinoma.

Currently recruiting

MEGA-ROX

The Mega Randomised Registry Trial Comparing Conservative vs.Liberal OXygenation Targets (Mega-ROX) (ACTRN12620000391976)

No longer recruiting

MEMENTO

MEMENTO - A Phase 4, Single-arm, Open-label Clinical Study to Evaluate Mavacamten in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy to Assess the Impact on Myocardial Structure with Cardiac Magnetic Resonance Imaging [CMR] (NCT06112743)

Currently recruiting

MHT vs SSRI

A randomised double-blinded interventional trial of estradiol and zoloft to treat menopausal depression (ACTRN12624000475549p)

Currently recruiting

MIDAS 2

A Phase III, Multicentre, Prospective, Randomised, Placebo-controlled, Double-blind, Parallel group, with an adaptive sample size re-estimation study in Stroke Survivors (ACTRN12618000602224)