Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Cell-free DNA chromosome copy number variations predict outcomes in plasma cell myeloma

Qiang, Wanting; Jin, Lina; Luo, Tiancheng; Jia, Yanchun; Lu, Jing; Liu, Jin; He, Haiyan; Qian, Ziliang; Mithraprabhu, Sridurga; Liang, Yang; Gale, Robert Peter; Tao, Xia; Wu, Depei; Du, Juan

(2023), Blood Cancer Journal, 13(1), 136

DOI: 10.1038/s41408-023-00904-9

Prehospital Tranexamic Acid for Severe Trauma

PATCH-Trauma Investigators and the ANZICs Clinical Trials Group; Gruen, R; Mitra, B; Bernard, SA; McArthur, C; Burns, B; Gantner, D; Maegele, MG.; Cameron, P; Dicker, BL.; Forbes, AB; Hurford, S.; Martin, CA; Mazur, SM; Medcalf RL; Murray LJ, Myles PS, Ng SJ, Pitt V, Rashford S,... Young PJ

(2023), New England Journal of Medicine, 389(2), 127-136

DOI: 10.1056/NEJMoa2215457

Platelet-targeted thrombolysis for treatment of acute ischemic stroke

Palazzolo, Jason Sam; Ale, Anukreity; Ho, Kwai Ching Heidi; Jagdale, Shweta; Broughton, Bradley Randal Scott; Medcalf, Robert Lindsay; Wright, David Keith; Alt, Karen Maria; Hagemeyer, Christoph Eugen; Niego, Be'eri

(2023), Blood Advances, 7(4), 561-574

DOI: 10.1182/bloodadvances.2021006691

Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia

Moujalled, Donia; Brown, Fiona Claire; Chua, Chong Chyn; Dengler, Michael A.; Pomilio, Giovanna; Anstee, Natasha; Litalien, Veronique; Thompson, Ella R.; Morley, Thomas; Macraild, Sarah; Tiong, Ing Soo; Morris, Rhiannon; Dun, Karen; Zordan, Adrian; Shah,

(2023), Blood, 141(6), 634–644

DOI: 10.1182/blood.2022016090

Circulating tumour DNA analysis predicts relapse and improves risk stratification in primary refractory multiple myeloma

Mithraprabhu, Sridurga; Reynolds, John; Turner, Rose Elisabeth Juniper; Quach, Hang; Horvath, Noemi; Kerridge, Ian H.; Kalff, Anna; Bergin, Krystal Frances; Hocking, Jay; Yuen, Flora; Khong, Tiffany Tee Fern; Durie, Brian G.M.; Spencer, Andrew

(2023), Blood Cancer Journal, 13(1), 25

DOI: 10.1038/s41408-023-00796-9

Symptomatic benefit of momelotinib in patients with myelofibrosis

Mesa, Ruben A; Hudgens, Stacie; Floden, Lysbeth; Harrison, Claire N.; Palmer, Jeanne; Gupta, Vikas; McLornan, Donal; McMullin, Mary Frances; Kiladjian, Jean Jaques; Foltz, Lynda M.; Platzbecker, Uwe; Fox, Maria Laura; Mead, Adam; Ross, David Morrall; Oh,

(2023), Cancer Medicine, 12(9), 10612-10624

DOI: 10.1002/cam4.5799

Global coagulation assays in patients with chronic kidney disease and their role in predicting thrombotic risk

Lim, Hui Yin; Lui, Brandon; Tacey, Mark Alan; Barit, David; Patel, Sheila K.; Donnan, Geoffrey; Nandurkar, Harshal Hanumant; Burrell, Louise M.; Ho, Prahlad Wei Soon

(2023), Thrombosis Research, 226, 127-135

DOI: 10.1016/j.thromres.2023.04.016

Platelet-activating functional assay resolution in vaccine-induced immune thrombotic thrombocytopenia

Lee, Christine S.M.; Clarke, Lisa; Kershaw, Geoffrey W.; Tohidi-Esfahani, Ibrahim; Brighton, Timothy A.; Chunilal, Sanjeev; Favaloro, Emmanuel J; Tran, Huyen; Chen, Vivien M

(2023), Research and Practice in Thrombosis and Haemostasis, 7(3), 100128

DOI: 10.1016/j.rpth.2023.100128

Uptake-Dependent and -Independent Effects of Fibroblasts-Derived Extracellular Vesicles on Bone Marrow Endothelial Cells from Patients with Multiple Myeloma

Lamanuzzi, Aurelia; Saltarella, Ilaria; Reale, Antonia; Melaccio, Assunta; Solimando, Antonio Giovanni; Altamura, Concetta; Tamma, Grazia; Storlazzi, Clelia Tiziana; Tolomeo, Doron; Desantis, Vanessa; Mariggiò, Maria Addolorata; Desaphy, Jean François; Sp

(2023), Biomedicines, 11(5), 1400

DOI: 10.3390/biomedicines11051400

UHRF1/UBE2L6/UBR4-mediated ubiquitination regulates EZH2 abundance and thereby melanocytic differentiation phenotypes in melanoma

Kuser Abali, Gamze; Zhang, Youfang; Szeto, Pacman; Zhao, Peinan; Masoumi Moghaddam, Samar; Fedele, Clare Grace; Leece, Isobel Anne Murrell; Huang, Cheng; Cheung, Yi Ting; Ameratunga, Malaka; Noguchi, Fumihito; Andrews, Miles Cameron Gregory; Wong, Nichola

(2023), Oncogene, 42(17), 1360–1373

DOI: 10.1038/s41388-023-02631-8

Editorial: Thrombosis meets inflammation

Kolev, Krasimir; Medcalf, Robert Lindsay

(2023), Frontiers in Immunology, 14

DOI: 10.3389/fimmu.2023.1303385

Characteristics and outcomes of patients with acute promyelocytic leukemia and extreme hyperleukocytosis at presentation

Iland, Harry J.; Russell, Nigel; Dillon, Richard; Schuh, Andre C.; Tedjaseputra, Aditya; Wei, Andrew; Khwaja, Asim; Knapper, Steven; Lane, Steven W.; Reynolds, John; McMullin, Mary Frances; Martin, Annalise M.; Tan, Peter; Taussig, David Christopher; Wong

(2023), Blood Advances, 7(11), 2580-2585

DOI: 10.1182/bloodadvances.2022007126

Poly(ethylene glycol) Cross-Linked Antibody Nanoparticles for Tunable Biointeractions

Hu, Yingjie; Cortez-Jugo, Christina; Ju, Yi; Zheng, Tian; Zhou, Jiajing; Lin, Zhixing; De Rose, Robert; Hagemeyer, Christoph Eugen; Alt, Karen Maria; Caruso, Frank

(2023), Chemistry of Materials, 35(13), 4965−4978

DOI: 10.1021/acs.chemmater.3c00323

Chemoselective Methionine Labelling of Recombinant Trastuzumab Shows High In Vitro and In Vivo Tumour Targeting

Hashad, Rania Atallah Ibrahim Atallah; Jap, Edwina; Casey, Joanne Lois; Ho, Yee Ting Candace; Wright, Alexander Jackson Ivan; Thalmann, Claudia Martha; Sleeman, Mark; Lupton, David; Hagemeyer, Christoph Eugen; Cryle, Max; Robert, Remy; Alt, Karen Maria

(2023), CHEMISTRY-A EUROPEAN JOURNAL, 29(11), e202202491

DOI: 10.1002/chem.202202491

Improving the rate of inferior vena cava filter retrieval through multidisciplinary engagement.

Hannah Stevens, Hadley Bortz, Sharon Chao, Radha Ramanan, Warren Clements, Karlheinz Peter, James D McFadyen, Huyen Tran

(2023), Research and practice in thrombosis and haemostasis, 7(1), 100040

DOI: 10.1016/j.rpth.2023.100040

Association Between Thromboelastometry Identified Hypercoagulability and Thromboembolic Complications After Arthroplasty

Gurunathan, Usha; Chiang, Lily; Hines, Joel; Pearse, Bronwyn Louise; McKenzie, Scott C.; Hay, Karen; Mullany, Daniel V; Nandurkar, Harshal Hanumant; Eley, Victoria

(2023), CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, 29, 1-10

DOI: 10.1177/10760296231199737

CRISPR–ChIP reveals selective regulation of H3K79me2 by Menin in MLL leukemia

Gilan, Omer; Talarmain, Laure; Bell, Charles C.; Neville, Daniel Christopher; Knezevic, Kathy; Ferguson, Daniel Thomas; Boudes, Marion; Chan, Yih Chih; Davidovich, Chen; Lam, Enid Y N; Dawson, Mark A.

(2023), Nature Structural & Molecular Biology, 30, 1592-1606

DOI: 10.1038/s41594-023-01087-4

A systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA and adenovirus vectored vaccines.

Feargal J Ryan, Todd S Norton, Conor McCafferty, Stephen J Blake, Natalie E Stevens, Jane James, Georgina L Eden, Yee C Tee, Saoirse C Benson, Makutiro G Masavuli, Arthur E L Yeow, Arunasingam Abayasingam, David Agapiou, Hannah Stevens, Jana Zecha, Nicole L Messina, Nigel Curtis, Vera Ignjatovic, Paul Monagle, Huyen Tran, James D McFadyen, Rowena A Bull, Branka Grubor-Bauk, Miriam A Lynn, Rochelle Botten, Simone E Barry, David J Lynn

(2023), CELL REPORTS MEDICINE, 4(3), 100971

DOI: 10.1016/j.xcrm.2023.100971

Extracellular vesicles as next generation immunotherapeutics.

David W Greening, Rong Xu, Anukreity Ale, Christoph E Hagemeyer, Weisan Chen

(2023), Seminars in cancer biology, 90, 73-100

DOI: 10.1016/j.semcancer.2023.02.002

Peripheral Blood CD34 Donor Chimerism has Greater Clinical Utility Than CD3 for Detecting Relapse after Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia or Myelodysplastic Syndrome

Das, Tongted Phumoonna; North, Daniel; Fleming, Shaun; Tan, Joanne L.C.; Ivey, Adam; Cummings, Nicholas J.; Spencer, Andrew; Patil, Sushrut; Widjaja, Jacqueline M L; Swain, Michael I.; Bourke, Catherine; O'Brien, Maureen E.; Kliman, David S.; Curtis, Davi

(2023), Transplantation and Cellular Therapy, 29(7), 454.e1-454.e8

DOI: 10.1016/j.jtct.2023.03.025

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