Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Current and future strategies to monitor and manage coagulation in ECMO patients

Zeibi Shirejini, Saeedreza; Carberry, Josie Joy; McQuilten, Zoe; Burrell, Aidan John Cobb; Gregory, Shaun David; Hagemeyer, Christoph Eugen

(2023), Thrombosis Journal, 21(1), 11

DOI: 10.1186/s12959-023-00452-z

Shear-Responsive Drug Delivery Systems in Medical Devices

Zeibi Shirejini, Saeedreza; Carberry, Josie Joy; Alt, Karen Maria; Gregory, Shaun David; Hagemeyer, Christoph Eugen

(2023), Advanced Functional Materials, 33(37), 2303717

DOI: 10.1002/adfm.202303717

Efficacy and safety of fitusiran prophylaxis in people with haemophilia A or haemophilia B with inhibitors (ATLAS-INH)

Young, Guy; Srivastava, Alok; Kavakli, Kaan; Ross, Cecil R.; Sathar, Jameela; You, Chur Woo; Tran, Huyen; Sun, Jing; Wu, Runhui; Poloskey, Stacey; Qiu, Zhiying; Kichou, Salim; Andersson, Shauna; Mei, Baisong; Rangarajan, Savita

(2023), Lancet, 401(10386), 1427-1437

DOI: 10.1016/S0140-6736(23)00284-2

Nogo receptor-Fc delivered by haematopoietic cells enhances neurorepair in a multiple sclerosis model

Ye, Sining; Theotokis, Paschalis; Lee, Jae Young; Kim, Min Joung; Nheu, Danica; Ellen, Olivia; Bedford, Thomas James Athelstan; Ramanujam, Padmanabhan; Wright, David Keith; McDonald, Stuart John; Alrehaili, Amani Ahmed B; Bakhuraysah, Maha Mahfouz A; Kang

(2023), Brain Communications, 5(2), fcad108

DOI: 10.1093/braincomms/fcad108

Current challenges in the prevention and management of post-thrombotic syndrome—towards improved prevention

Wang, Julie; Smeath, Elise; Lim, Hui Yin; Nandurkar, Harshal Hanumant; Kok, Hong Kuan; Ho, Prahlad Wei Soon

(2023), International Journal of Hematology, 118, 547-67

DOI: 10.1007/s12185-023-03651-6

DOAC-stop can remove direct oral anticoagulants and allow analysis by global coagulation assays

Wang, Julie; Lim, Hui Yin; Nandurkar, Harshal Hanumant; Ho, Prahlad Wei Soon

(2023), International Journal of Laboratory Hematology, 453, 360-7

DOI: 10.1111/ijlh.14020

Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM)

Verstovsek, Srdan; Gerds, Aaron; Vannucchi, Alessandro Maria; Al-Ali, Haifa Kathrin; Lavie, David; Kuykendall, Andrew T.; Grosicki, Sebastian; Iurlo, Alessandra; Goh, Yeow Tee; Lazaroiu, Mihaela C.; Egyed, Miklos; Fox, Maria Laura; McLornan, Donal; Harris

(2023), Lancet, 401(10373), 269-280

DOI: 10.1016/S0140-6736(22)02036-0

Response adaptive salvage with KTd and ASCT for functional high-risk multiple myeloma—The Australasian Leukemia and Lymphoma Group (ALLG) MM17 Trial

Turner, Rose; Quach, Hang; Horvath, Noemi; Kerridge, Ian H.; Lee, E.; Morris, Emma C.; Kalff, Anna; Khong, Tiffany Tee Fern; Reynolds, John; Spencer, Andrew

(2023), British Journal of Haematology, 202(3), 530-538

DOI: 10.1111/bjh.18914

Thrombus remodelling by reversible and irreversible P2Y12 inhibitors

Tunströmer, Kjersti; Faxälv, Lars; Larsson, Pia Maria Kristina; Lindahl, Tomas L.; Henrik Robin Boknas, Niklas

(2023), Platelets, 34(1), 2157805

DOI: 10.1080/09537104.2022.2157805

STAT5 activation promotes progression and chemotherapy resistance in early T-cell precursor acute lymphoblastic leukemia

Tremblay, Cedric; Saw, Jesslyn Mei Yoong; Boyle, Jacqueline Annette; Haigh, Katharina; Litalien, Veronique; McCalmont, Hannah; Evans, Kathryn; Lock, Richard B; Jane, Stephen Marsden; Haigh, Jody Jonathan; Curtis, David John

(2023), Blood, 142(3), 274-289

DOI: 10.1182/blood.2022016322

PRMT5 inhibitors for lower-risk myelodysplasia

Terzic, Andrej; Curtis, David John

(2023), Leukemia Research, 135

DOI: 10.1016/j.leukres.2023.107415

Venetoclax treatment in patients with cancer has limited impact on circulating T and NK cells

Teh, Charis En Yi; Peng, Hongke; Luo, Meng Xiao; Tan, Tania; Trussart, Marie; Howson, Lauren Jane; Chua, Chong Chyn; Muttiah, Christine; Brown, Fiona Claire; Ritchie, Matthew E.; Wei, Andrew; Roberts, Andrew W.; Bryant, Vanessa L.; Anderson, Mary Ann; Lin

(2023), Blood Advances, 7(12), 2733-2745

DOI: 10.1182/bloodadvances.2022008221

A sequential cohort study evaluating single-agent KappaMab and KappaMab combined with lenalidomide and low-dose dexamethasone in relapsed and/or refractory kappa light chain-restricted multiple myeloma (AMaRC 01-16)

Spencer, Andrew; Kalff, Anna; Shortt, Jake; Quach, Hang; Wallington-Gates, Craig ; Reynolds, John; Walker, Patricia Ann; Harrison, Simon James; Dunn, Rosanne D.; Wellard, Cameron James

(2023), British Journal of Haematology, 202(4), 801-811

DOI: 10.1111/bjh.18955

Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes

Sparbier, Christina E.; Gillespie, Andrea; Gomez, Juliana; Kumari, Nishi; Motazedian, Ali; Chan, Kah Lok; Bell, Charles C.; Gilan, Omer; Chan, Yih Chih; Popp, Sarah; Gough, Daniel James; Eckersley-Maslin, Melanie A.; Dawson, Sarah-Jane; Lehner, Paul J.; S

(2023), Nature Cell Biology, 25(2), 258-272

DOI: 10.1038/s41556-022-01056-x

Tissue-type plasminogen activator induces conditioned receptive field plasticity in the mouse auditory cortex

Smart, Caitlin; Mitchell, Anna; McCutcheon, Fiona; Medcalf, Robert Lindsay; Thiele, Alexander

(2023), iScience, 26(2), 105947

DOI: 10.1016/j.isci.2023.105947

Zanubrutinib for the treatment of relapsed/refractory hairy cell leukemia

Si Lun Tam, Constantine; Trotman, Judith; Opat, Stephen; Stern, Jennifer C.; Allewelt, Heather; By, Kunthel; Novotny, William; Huang, Jane; Tedeschi, Alessandra

(2023), Blood Advances, 7(12), 2884-2887

DOI: 10.1182/bloodadvances.2022008990

Zanubrutinib, Alone and in Combination with Tislelizumab, for the Treatment of Richter Transformation of Chronic Lymphocytic Leukemia

Si Lun Tam, Constantine; Munoz-Garcia, Javier; Cull, Gavin; Opat, Stephen; Allewelt, Heather; Zhang, Xiaoping; Stern, Jennifer C.; Hilger, James D.; By, Kunthel; Cohen, Aileen; Tedeschi, Alessandra

(2023), HemaSphere, 7(4), e870

DOI: 10.1097/HS9.0000000000000870

Correction

Si Lun Tam, Constantine; Muñoz, Javier L.; Seymour, John Francis; Opat, Stephen

(2023), Blood Cancer Journal, 13(1), 154

DOI: 10.1038/s41408-023-00926-3

An Engineered Nanosugar Enables Rapid and Sustained Glucose-Responsive Insulin Delivery in Diabetic Mice.

Rong Xu, Sukhvir Kaur Bhangu, Karly C Sourris, Domitilla Vanni, Marc-Antoine Sani, John A Karas, Karen Alt, Be'eri Niego, Anukreity Ale, Quinn A Besford, Brendan Dyett, Joshua Patrick, Irena Carmichael, Jonathan E Shaw, Frank Caruso, Mark E Cooper, Christoph E Hagemeyer, Francesca Cavalieri

(2023), Advanced materials, 21(35), e2210392

DOI: 10.1002/adma.202210392

Cellular distribution of IDH mutations in AML during morphologic remission

Ramanan, Radha; Tiong, Ing Soo; Ivey, Adam; Ong, Doen Ming; Brown, Fiona Claire; Chua, Chong Chyn; Das, Tongted Phumoonna; Curtis, David John

(2023), Leukemia Research, 124

DOI: 10.1016/j.leukres.2022.106993