Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Higher infused lymphocyte dose predicts higher lymphocyte recovery, which in turn, predicts superior overall survival following autologous hematopoietic stem cell transplantation for multiple myeloma

Hiwase DK, Hiwase S, Bailey M, Bollard G, Schwarer AP

(2008), Biol Blood Marrow Transplant, 14(1), 116-24

Overlapping and distinct roles for PI3Kbeta and gamma isoforms in S1P-induced migration of human and mouse endothelial cells

Heller R, Chang Q, Ehrlich G, Hsieh SN, Schoenwaelder SM, Kuhlencordt PJ, Preissner KT, Hirsch E, Wetzker R

(2008), Cardiovasc Res, 80(1), 96-105

Targeting the PI3K p110alpha isoform inhibits medulloblastoma proliferation, chemoresistance, and migration

Guerreiro AS, Fattet S, Fischer B, Shalaby T, Jackson SP, Schoenwaelder SM, Grotzer MA, Delattre O, Arcaro A

(2008), Clin Cancer Res, 14(21), 6761-9

Dissecting isoform selectivity of PI3K inhibitors: the role of non-conserved residues in the catalytic pocket

Frazzetto M, Suphioglu C, Zhu J, Schmidt-Kittler O, Jennings IG, Cranmer SL, Jackson SP, Kinzler KW, Vogelstein B, Thompson PE

(2008), Biochem J, 414(3), 383-90

Essential role of platelet activation via protease activated receptor 4 in tissue factor-initiated inflammation

Busso N, Chobaz-Peclat V, Hamilton J, Spee P, Wagtmann N, So A

(2008), Arthritis Res Ther, 10(2), R42

Pegylated liposomal doxorubicin plus bortezomib in relapsed or refractory multiple myeloma: efficacy and safety in patients with renal function impairment

Blade J, Sonneveld P, San Miguel JF, Sutherland HJ, Hajek R, Nagler A, Spencer A, Robak T, Cibeira MT, Zhuang SH, Harousseau JL, Orlowski RZ; DOXIL-MMY-3001 Study Investigators

(2008), Clin Lymphoma Myeloma, 8(6), 352-5

Urinary cytology in multiple myeloma

Patil S, Schwarer A, McLean C

(2008), Cytopathology, 19(2), 130-1

Expression and purification of the minor histocompatibility antigen, HA-1H generated in Escherichia coli

Etto TL, Stewart LA, Nguyen TH, Williamson NA, Purcell AW, Schwarer AP

(2007), Protein Expr Purif, 54(1), 176-82

Development of fatal bortezomib induced acute lung injury despite concurrent therapy with high-dose dexamethasone

Chew E, Filshie R, Wei A

(2007), Leuk Lymphoma, 48(1), 212-3

Rituximab responsive immune thrombocytopenic purpura in an adult with underlying autoimmune lymphoproliferative syndrome due to a splice-site mutation (IVS7+2T>C) affecting the Fas gene

Wei A, Cowie T

(2007), Eur J Haematol, 79(4), 363-6

Mouse serpins and transgenic studies

Askew DJ, Couglin P, Bird PI

(2007), In: Silverman GA, Lomas DA (eds). Chapter 4. Molecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity. World Scientific, Singapore, 101-29

Par4 is required for platelet thrombus propagation but not fibrin generation in a mouse model of thrombosis

Vandendries ER, Hamilton JR, Coughlin SR, Furie B, Furie BC

(2007), Proc Natl Acad Sci USA, 104(1), 288-92

Pilot study of an outpatient-based approach for advanced lymphoma using vinorelbine, gemcitabine and filgrastim

Spencer A, Reed K, Arthur C

(2007), Intern Med J, 37(11), 760-6

A randomized comparison of empiric or pre-emptive antibiotic therapy after hematopoietic stem cell transplantation

Slavin MA, Grigg AP, Schwarer AP, Szer J, Spencer A, Sainani A, Thursky KA, Roberts AW

(2007), Bone Marrow Transplant, 40(2), 157-63

PKC412 demonstrates JNK-dependent activity against human multiple myeloma cells

Sharkey J, Khong T, Spencer A

(2007), Blood, 109(4), 1712-9

Identification of a unique co-operative phosphoinositide 3-kinase signalling mechanism regulating integrin alpha IIb beta 3 adhesive function in platelets

Schoenwaelder SM, Ono A, Sturgeon S, Chan SM, Mangin P, Maxwell MJ, Turnbull S,Mulchandani M, Anderson K, Kauffenstein G, Rewcastle GW, Kendall J, Gachet C, Salem HH, Jackson SP

(2007), J Biol Chem, 282(39), 28648-58

Molecular characterization of centerin, a germinal centre cell serpin

Paterson MA, Horvath AJ, Pike RN, Coughlin PB

(2007), Biochem J, 405(3), 489-94

Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: combination therapy improves time to progression

Orlowski RZ, Nagler A, Sonneveld P, Bladé J, Hajek R, Spencer A, San Miguel J, Robak T, Dmoszynska A, Horvath N, Spicka I, Sutherland HJ, Suvorov AN, Zhuang SH, Parekh T, Xiu L, Yuan Z, Rackoff W, Harousseau JL

(2007), J Clin Oncol, 25(25), 3892-901

Fibrinolysis, inflammation, and regulation of the plasminogen activating system

Medcalf RL

(2007), J Thromb Haemost, 5 (Suppl 1), 132-42

Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation

Maxwell MJ, Westein E, Nesbitt WS, Giuliano S, Dopheide SM, Jackson SP

(2007), Blood, 109(2), 566-76

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