Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Dynamics of platelet thrombus formation

Jackson SP, Nesbitt WS, Westein E

(2009), J Thromb Haemost, 7, Suppl 1, 17-20

Protease-activated receptors as targets for antiplatelet therapy

Hamilton JR

(2009), Blood Rev, 23(2), 61-5

Atherosclerosis proceeds independently of thrombin-induced platelet activation in ApoE-/- mice

Hamilton JR, Cornelissen I, Mountford JK, Coughlin SR

(2009), Atherosclerosis, 205(2), 427-32

Non-redundant roles of phosphoinositide 3-kinase isoforms alpha and beta in glycoprotein VI-induced platelet signaling and thrombus formation

Gilio K, Munnix IC, Mangin P, Cosemans JM, Feijge MA, van der Meijden PE, Olieslagers S, Chrzanowska-Wodnicka MB, Lillian R, Schoenwaelder S, Koyasu S, Sage SO, Jackson SP, Heemskerk JW

(2009), J Biol Chem, 284(49), 33750-62

Preliminary evidence of disease response to the pan deacetylase inhibitor panobinostat (LBH589) in refractory Hodgkin lymphoma

Dickinson M, Ritchie D, DeAngelo DJ, Spencer A, Ottmann OG, Fischer T, Bhalla KN, Liu A, Parker K, Scott JW, Bishton M, Prince HM

(2009), Br J Haematol, 147(1), 97-101

Clinical and immunohistochemical features associated with a response to bortezomib in patients with multiple myeloma

Dawson MA, Opat SS, Taouk Y, Donovan M, Zammit M, Monaghan K, Horvath N, Roberts AW, Prince HM, Hertzberg M, McLean CA, Spencer A

(2009), Clin Cancer Res, 15(2), 714-22

Prognostically significant cytotoxic T cell clones are stimulated after thalidomide therapy in patients with multiple myeloma

Brown RD, Spencer A, Ho PJ, Kennedy N, Kabani K, Yang S, Sze DM, Aklilu E, Gibson J, Joshua DE

(2009), Leuk Lymphoma, 50(11), 1860-4

Is thrombin the problem or (dis)solution?

Arthur JF, Jackson SP

(2009), Blood, 113(24), 6046-7

Measuring soluble platelet glycoprotein VI in human plasma by ELISA

Al-Tamimi M, Mu FT, Moroi M, Gardiner EE, Berndt MC, Andrews RK

(2009), Platelets, 20(3), 143-9

Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding

Al-Tamimi M, Mu FT, Arthur JF, Shen Y, Moroi M, Berndt MC, Andrews RK, Gardiner EE

(2009), Platelets, 20(2), 75-82

Disease status at autologous stem cell transplantation and the cell of origin phenotype are important predictors of outcome in patients with neurologic (central nervous system) relapse of diffuse large B-cell lymphoma undergoing autologous stem cell......

Patil S, Spencer A, Schwarer A, Avery S, Ritchie D, Opat S, Wei A, McLean C

(2009), Leuk Lymphoma, 50(12), 1964-8

The novel histone deacetylase inhibitors metacept-1 and metacept-3 potently increase HIV-1 transcription in latently infected cells

Shehu-Xhilaga M, Rhodes D, Wightman F, Liu HB, Solomon A, Saleh S, Dear AE, Cameron PU, Lewin SR

(2009), AIDS, 23(15), 2047-50

Bortezomib: putting mantle cell lymphoma on death row

Wei AH, Roberts AW

(2008), Leuk Lymphoma, 49(4), 657-8

Boosting platelet production

Wei A, Jackson SP

(2008), Nat Med, 14(9), 917-8

Prosthetic pulmonary valve thrombosis in pregnancy successfully treated with thrombolysis

Wei A, Alison J, Goldstein J, Tippett C, Coughlan PB

(2008), Intern Med J, 38(2), 142-3

Lenalidomide plus dexamethasone is more effective than dexamethasone alone in patients with relapsed or refractory multiple myeloma regardless of prior thalidomide exposure

Wang M, Dimopoulos MA, Chen C, Cibeira MT, Attal M, Spencer A, Rajkumar SV, Yu Z, Olesnyckyj M, Zeldis JB, Knight RD, Weber DM

(2008), Blood, 112(12), 4445-51

A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice

Vinh A, Gaspari TA, Liu HB, Dousha LF, Widdop RE, Dear AE

(2008), J Vasc Res, 45(2), 143-52

Dual P2Y 12 receptor signaling in thrombin-stimulated platelets--involvement of phosphoinositide 3-kinase beta but not gamma isoform in Ca2+ mobilization and procoagulant activity

van der Meijden PE, Schoenwaelder SM, Feijge MA, Cosemans JM, Munnix IC, Wetzker R, Heller R, Jackson SP, Heemskerk JW

(2008), FEBS J, 275(2), 371-85

Enhanced immune system regeneration in humans following allogeneic or autologous hemopoietic stem cell transplantation by temporary sex steroid blockade

Sutherland JS, Spyroglou L, Muirhead JL, Heng TS, Prieto-Hinojosa A, Prince HM, Chidgey AP, Schwarer AP, Boyd RL

(2008), Clin Cancer Res, 14(4), 1138-49

Renal safety of zoledronic acid with thalidomide in patients with myeloma: a pharmacokinetic and safety sub-study

Spencer A, Roberts A, Kennedy N, Ravera C, Cremers S, Bilic S, Neeman T, Copeman M, Schran H, Lynch K

(2008), BMC Clin Pharmacol, 8, 2

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