Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Pathologic shear triggers shedding of vascular receptors: a novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels

Al-Tamimi M, Tan CW, Qiao J, Pennings GJ, Javadzadegan A, Yong AS, Arthur JF, Davis AK, Jing J, Mu FT, Hamilton JR, Jackson SP, Ludwig A, Berndt MC, Ward CM, Kritharides L, Andrews RK, Gardiner EE

(2012), Blood, 119(18), 4311-20

Focusing on plasma glycoprotein VI

Al-Tamimi M, Arthur JF, Gardiner E, Andrews RK

(2012), Thromb Haemost, 107(4), 648-55

Interleukin 11 regulates endometrial cancer cell adhesion and migration via STAT3

Lay V, Yap J, Sonderegger S, Dimitriadis E

(2012), Int J Oncol, 41(2), 759-64

Combined loss of cRel/p50 subunits of NF-ΚB leads to impaired innate host response in sepsis

Courtine E, Cagnard N, Mazzolini J, Antona M, Pène F, Fitting C, Jacques S, Rousseau C, Niedergang F, Gerondakis S, Chiche JD, Ouaaz F, Mira JP

(2012), Innate Immun, 18(5), 753-63

Failure of haematopoietic recovery overcome by SCT despite invasive mucormycosis infection

Grigoriadis G, Chang CC, Walker P, Patil S, Avery S, Morrissey O, Spencer A

(2012), Bone Marrow Transplant, 47(4), 591-2

Rivaroxaban and false positive lupus anticoagulant testing

Merriman E, Kaplan Z, Butler J, Malan E, Gan E, Tran H

(2011), Thromb Haemost, 105(2), 385-6

An event of shear importance

Andrews RK, Berndt MC

(2011), Blood, 117(1), 5-7

Contribution of conserved lysine residues in the alpha2-antiplasmin C terminus to plasmin binding and inhibition

Lu BG, Sofian T, Law RH, Coughlin PB, Horvath AJ

(2011), J Biol Chem, 286(28), 24544-52

Compartment- and context-specific changes in tissue-type plasminogen activator (tPA) activity following brain injury and pharmacological stimulation

Sashindranath M, Samson AL, Downes CE, Crack PJ, Lawrence AJ, Li QX, Ng AQ, Jones NC, Farrugia JJ, Abdella E, Vassalli JD, Madani R, Medcalf RL

(2011), Lab Invest, 91(7), 1079-91

Methods to measure the kinetics of protease inhibition by serpins

Horvath AJ, Lu BG, Pike RN, Bottomley SP

(2011), Methods Enzymol, 501, 223-35

Plasminogen activator inhibitor type 2: still an enigmatic serpin but a model for gene regulation

Medcalf R

(2011), Methods Enzymol, 499, 105-34

Phosphatidylinositol(4,5)bisphosphate coordinates actin-mediated mobilization and translocation of secretory vesicles to the plasma membrane of chromaffin cells

Wen PJ, Osborne SL, Zanin M, Low PC, Wang HT, Schoenwaelder SM, Jackson SP, Wedlich-Söldner R, Vanhaesebroeck B, Keating DJ, Meunier FA

(2011), Nat Commun, 2, 491

Prothrombin complex concentrates used alone in urgent reversal of warfarin anticoagulation

Tran H, Collecutt M, Whitehead S, Salem HH

(2011), Intern Med J, 41(4), 337-43

Structural and hydrodynamic simulation of an acute stenosis-dependent thrombosis model in mice

Tovar-Lopez FJ, Rosengarten G, Khoshmanesh K, Westein E, Jackson SP, Nesbitt WS, Mitchell A

(2011), J Biomech, 44(6), 1031-9

Allelic imbalance of tissue-type plasminogen activator (t-PA) gene expression in human brain tissue

Tjarnlund-Wolf A, Hultman K, Curtis MA, Faull RL, Medcalf RL, Jern C

(2011), Thromb Haemost, 105(6), 945-53

Distinct roles in NKT cell maturation and function for the different transcription factors in the classical NF-ΚB pathway

Stankovic S, Gugasyan R, Kyparissoudis K, Grumont R, Banerjee A, Tsichlis P, Gerondakis S, Godfrey DI

(2011), Immunol Cell Biol, 89(2), 294-303

Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets

Schoenwaelder SM, Jarman KE, Gardiner EE, Hua M, Qiao J, White MJ, Josefsson EC, Alwis I, Ono A, Willcox A, Andrews RK, Mason KD, Salem HH, Huang DC, Kile BT, Roberts AW, Jackson SP

(2011), Blood, 118(6), 1663-74

Managing multiple myeloma in the elderly: are we making progress?

Quach H, Prince HM, Spencer A

(2011), Expert Rev Hematol, 4(3), 301-15

Asparaginase in the management of adult acute lymphoblastic leukaemia: is it used appropriately?

Patil S, Coutsouvelis J, Spencer A

(2011), Cancer Treat Rev, 37(3), 202-7

Rapid platelet accumulation leading to thrombotic occlusion

Para A, Bark D, Lin A, Ku D

(2011), Ann Biomed Eng, 39(7), 1961-71

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