Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes

Niego B, Freeman R, Puschmann TB, Turnley AM, Medcalf RL

(2012), Blood, 119(20), 4752-61

Wnt1 is anti-lymphangiogenic in a melanoma mouse model

Niederleithner H, Heinz M, Tauber S, Bilban M, Pehamberger H, Sonderegger S, Knöfler M, Bracher A, Berger W, Loewe R, Petzelbauer P

(2012), J Invest Dermatol, 132(9), 2235-44

A live cell micro-imaging technique to examine platelet calcium signaling dynamics under blood flow

Nesbitt WS, Harper IS, Schoenwaelder SM, Yuan Y, Jackson SP

(2012), Methods Mol Biol, 788, 73-89

Plasminogen activation and thrombolysis for ischemic stroke

Medcalf RL, Davis SM

(2012), Int J Stroke, 7(5), 419-25

Desmoteplase: discovery, insights and opportunities for ischaemic stroke

Medcalf RL

(2012), Br J Pharmacol, 165(1), 75-89

Recommendations for the diagnosis and treatment of deep venous thrombosis and pulmonary embolism in pregnancy and the postpartum period

McLintock C, Brighton T, Chunilal S, Dekker G, McDonnell N, McRae S, Muller P, Tran H, Walters BN, Young L; Councils of the Society of Obstetric Medicine of Australia and New Zealand; Australasian Society of Thrombosis and Haemostasis

(2012), Aust N Z J Obstet Gynaecol, 52(1), 14-22

The contribution of thrombin-induced platelet activation to thrombus growth is diminished under pathological blood shear conditions

Lee H, Sturgeon SA, Jackson SP, Hamilton JR

(2012), Thromb Haemost, 107(2), 328-37

Safety and efficacy of targeting platelet proteinase-activated receptors in combination with existing anti-platelet drugs as antithrombotics in mice

Lee H, Sturgeon SA, Mountford JK, Jackson SP, Hamilton JR

(2012), Br J Pharmacol, 166(7), 2188-97

Physiology, pharmacology, and therapeutic potential of protease-activated receptors in vascular disease

Lee H, Hamilton JR

(2012), Pharmacol Ther, 134(2), 246-59

Role of histone acetylation in the stimulatory effect of valproic acid on vascular endothelial tissue-type plasminogen activator expression

Larsson P, Ulfhammer E, Magnusson M, Bergh N, Lunke S, El-Osta A, Medcalf RL, Svensson PA, Karlsson L, Jern S

(2012), PLoS One, 7(2), e31573

Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood

Jung SM, Moroi M, Soejima K, Nakagaki T, Miura Y, Berndt MC, Gardiner EE, Howes JM, Pugh N, Bihan D, Watson SP, Farndale RW

(2012), J Biol Chem, 287(35), 30000-13

Serum protein electrophoresis: a precautionary tale

Grigoriadis G, Shortt J, Quach H, Opat S

(2012), Pathology, 44(4), 371-3

Correct diagnosis of NK and T cell lymphomas

Gregory G, Fong CY, Whitehead S, Grigoriadis G

(2012), Pathology, 44(4), 383-4

The NET effect of clot formation

Gardiner EE, Ward CM, Andrews RK

(2012), J Thromb Haemost, 10(1), 133-5

Diesel exhaust particles impair platelet response to collagen and are associated with GPIbα shedding

Forestier M, Al-Tamimi M, Gardiner EE, Hermann C, Meyer SC, Beer JH

(2012), Toxicol In Vitro, 26(6), 930-8

ITAM receptor-mediated generation of reactive oxygen species in human platelets occurs via Syk-dependent and Syk-independent pathways

Arthur JF, Qiao J, Shen Y, Davis AK, Dunne E, Berndt MC, Gardiner EE, Andrews RK

(2012), J Thromb Haemost, 10(6), 1133-41

Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia

Glaser SP, Lee EF, Trounson E, Bouillet P, Wei A, Fairlie WD, Izon DJ, Zuber J, Rappaport AR, Herold MJ, Alexander WS, Lowe SW, Robb L, Strasser A

(2012), Genes Dev, 26(2), 120-5

Concise review: Blood relatives: formation and regulation of hematopoietic stem cells by the basic helix-loop-helix transcription factors stem cell leukemia and lymphoblastic leukemia-derived sequence 1

Curtis DJ, Salmon JM, Pimanda JE

(2012), Stem Cells, 30(6), 1053-8

Neurodevelopmental and neuropsychiatric behaviour defects arise from 14-3-3ζ deficiency

Cheah PS, Ramshaw HS, Thomas PQ, Toyo-Oka K, Xu X, Martin S, Coyle P, Guthridge MA, Stomski F, van den Buuse M, Wynshaw-Boris A, Lopez AF, Schwarz QP

(2012), Mol Psychiatry, 17(4), 451-66

Inside platelets...

Andrews RK, Gardiner EE

(2012), Blood, 119(4), 907-9

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