Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Shear-Dependent Platelet Aggregation

Rana, Akshita; Westein, Erik; Niego, Be'eri; Hagemeyer, Christoph E.

(2019), Front Cardiovasc Med, 6, 141

DOI: 10.3389/fcvm.2019.00141

Novel stenotic microchannels to study thrombus formation in shear gradients

Lui, Mathew; Gardiner, Elizabeth E.; Arthur, Jane F.; Pinar, Isaac; Lee, Woei Ming; Ryan, Kris; Carberry, Josie; Andrews, Robert K.

(2019), INT J MOL SCI, 20(12), 2967

DOI: 10.3390/ijms20122967

Corrupted DNA-binding specificity and ectopic transcription underpin dominant neomorphic mutations in KLF/SP transcription factors

Ilsley, Melissa D.; Huang, Stephen; Magor, Graham W.; Landsberg, Michael J.; Gillinder, Kevin R.; Perkins, Andrew C.

(2019), BMC GENOMICS, 20(1), 417

DOI: 10.1186/s12864-019-5805-z

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Iacobucci, Ilaria; Wen, Ji; Meggendorfer, Manja; Choi, John K.; Shi, Lei; Pounds, Stanley B.; Carmichael, Catherine L.; Masih, Katherine E.; Morris, Sarah M.; Lindsley, R. Coleman; Janke, Laura J.; Alexander, Thomas B.; Song, Guangchun; Qu, Chunxu; Li, Yongjin; Payne-Turner, Debbie; Tomizawa, Daisuke; Kiyokawa, Nobutaka; Valentine, Marcus; Valentine, Virginia; Basso, Giuseppe; Locatelli, Franco; Enemark, Eric J.; Kham, Shirley K.Y.; Yeoh, Allen E.J.; Ma, Xiaotu; Zhou, Xin; Sioson, Edgar; Rusch, Michael; Ries, Rhonda E.; Stieglitz, Elliot; Hunger, Stephen P.; Wei, Andrew H.; To, L. Bik; Lewis, Ian D.; D’Andrea, Richard J.; Kile, Benjamin T.; Brown, Anna L.; Scott, Hamish S.; Hahn, Christopher N.; Marlton, Paula; Pei, Deqing; Cheng, Cheng; Loh, Mignon L.; Ebert, Benjamin L.; Meshinchi, Soheil; Haferlach, Torsten; Mullighan, Charles G.

(2019), NAT GENET, 51(4), 694-704.

DOI: 10.1038/s41588-019-0375-1

Meta-analysis of Grainyhead-like dependent transcriptional networks

Mathiyalagan, Nishanthi; Miles, Lee B.; Anderson, Peter J.; Wilanowski, Tomasz; Grills, Brian L.; McDonald, Stuart J.; Keightley, M. Cristina; Charzynska, Agata; Dabrowski, Michal; Dworkin, Sebastian

(2019), GENES-BASEL, 10(11, 876

DOI: 10.3390/genes10110876

Toll-like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2

Liu, You Dong; Yu, Liang; Ying, Le; Balic, Jesse; Gao, Hugh; Deng, Nian Tao; West, Alison; Yan, Feng; Ji, Cheng Bo; Gough, Daniel; Tan, Patrick; Jenkins, Brendan J.; Li, Ji Kun

(2019), INT J CANCER, 144(12), 3056-3069.

DOI: 10.1002/ijc.32060

Structural basis for the recognition of nectin-like protein-5 by the human-activating immune receptor, DNAM-1

Deuss, Felix A; Watson, Gabrielle M; Goodall, Katharine J; Leece, Isobel; Chatterjee, Sayantani; Fu, Zhihui; Thaysen-Andersen, Morten; Andrews, Daniel M; Rossjohn, Jamie; Berry, Richard

(2019), J BIOL CHEM, 294(33), 12534-12546.

DOI: 10.1074/jbc.RA119.009261

Activated CD8+ T Cells Cause Long-Term Neurological Impairment after Traumatic Brain Injury in Mice

Daglas, Maria; Draxler, Dominik F.; Ho, Heidi; McCutcheon, Fiona; Galle, Adam; Au, Amanda E.; Larsson, Pia; Gregory, Julia; Alderuccio, Frank; Sashindranath, Maithili; Medcalf, Robert L.

(2019), CELL REP, 29(5), 1178-1191.e6.

DOI: 10.1016/j.celrep.2019.09.046

Ligand-Functionalized Poly(ethylene glycol) Particles for Tumor Targeting and Intracellular Uptake

Cui, Jiwei; Alt, Karen; Ju, Yi; Gunawan, Sylvia T.; Braunger, Julia A.; Wang, Ting Yi; Dai, Yunlu; Dai, Qiong; Richardson, Joseph J.; Guo, Junling; Björnmalm, Mattias; Hagemeyer, Christoph E.; Caruso, Frank

(2019), BIOMACROMOLECULES, 20(9), 3592-3600.

DOI: 10.1021/acs.biomac.9b00925

Carbohydrates@MOFs

Astria, Efwita; Thonhofer, Martin; Ricco, Raffaele; Liang, Weibin; Chemelli, Angela; Tarzia, Andrew; Alt, Karen; Hagemeyer, Christoph E.; Rattenberger, Johannes; Schroettner, Hartmuth; Wrodnigg, Tanja; Amenitsch, Heinz; Huang, David M.; Doonan, Christian J.; Falcaro, Paolo

(2019), MATER HORIZ, 6(5), 969-977.

DOI: 10.1039/c8mh01611a

Active Micropump-Mixer for Rapid Antiplatelet Drug Screening in Whole Blood

Szydzik, Crispin; Brazilek, Rose J.; Akbaridoust, Farzan; De Silva, Charitha; Moon, Mitchell; Marusic, Ivan; Ooi, Andrew S.H.; Nandurkar, Harshal H.; Hamilton, Justin R.; Mitchell, Arnan; Nesbitt, Warwick S.

(2019), ANAL CHEM, 91(16), 10830-10839.

DOI: 10.1021/acs.analchem.9b02486

Optical frequency comb based system for photonic refractive index sensor interrogation

Knoerzer, Markus; Szydzik, Crispin; Ren, Guanghui; Huertas, Cesar S.; Palmer, Sonya; Tang, Phuong; Nguyen, Thach G.; Bui, Lam; Boes, Andreas; Mitchell, Arnan

(2019), OPT EXPRESS, 27(15), 21532-21545.

DOI: 10.1364/OE.27.021532

Site-Specific Glycation and Chemo-enzymatic Antibody Sortagging for the Retargeting of rAAV6 to Inflamed Endothelium.

Hannah A Pearce, Hongwei Qian, Timothy U Connell, Dexing Huang, Claudia Gottstein, Paul S Donnelly, Karlheinz Peter, Paul Gregorevic, Christoph E Hagemeyer

(2019), MOL THER-METH CLIN D, 14, 261-269

DOI: 10.1016/j.omtm.2019.07.003

Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia.

Mark D McKenzie, Margherita Ghisi, Ethan P Oxley, Steven Ngo, Luisa Cimmino, Cécile Esnault, Ruijie Liu, Jessica M Salmon, Charles C Bell, Nouraiz Ahmed, Michael Erlichster, Matthew T Witkowski, Grace J Liu, Michael Chopin, Aleksandar Dakic, Emilia Simankowicz, Giovanna Pomilio, Tina Vu, Pavle Krsmanovic, Shian Su, Luyi Tian, Tracey M Baldwin, Daniela A Zalcenstein, Ladina DiRago, Shu Wang, Donald Metcalf, Ricky W Johnstone, Ben A Croker, Graeme I Lancaster, Andrew J Murphy, Shalin H Naik, Stephen L Nutt, Vitek Pospisil, Timm Schroeder, Meaghan Wall, Mark A Dawson, Andrew H Wei, Hugues de Thé, Matthew E Ritchie, Johannes Zuber, Ross A Dickins

(2019), Cell stem cell, 2(25), 258-272.e9

DOI: 10.1016/j.stem.2019.07.001

The PI 3-kinase PI3KC2α regulates mouse platelet membrane structure and function independently of membrane lipid composition.

Maria V Selvadurai, Rose J Brazilek, Mitchell J Moon, Jean-Yves Rinckel, Anita Eckly, Christian Gachet, Peter J Meikle, Harshal H Nandurkar, Warwick S Nesbitt, Justin R Hamilton

(2019), FEBS LETT, 1(593), 88-96

DOI: 10.1002/1873-3468.13295

The mode of anesthesia influences outcome in mouse models of arterial thrombosis.

Sashindranath M, Sturgeon SA, French S, Craenmehr DDD, Selan C, Freddi S, Johnson C, Cody SH, Nesbitt WS, Hamilton JR, Nandurkar HH

(2019), Res Pract Thromb Haemost, 3(2), 197-206

DOI: 10.1002/rth2.12184

New guidelines from the Thrombosis and Haemostasis Society of Australia and New Zealand for the diagnosis and management of venous thromboembolism

Tran HA, Gibbs H, Merriman E, Curnow JL, Young L, Bennett A, Wee TC, Chunilal SD, Ward CM, Baker R, Nandurkar H

(2019), MED J AUSTRALIA, 210(5), 227-35

DOI: 10.5694/mja2.50004

Compression force sensing regulates integrin αiIbβ3 adhesive function on diabetic platelets

Ju, Lining; McFadyen, James D.; Al-Daher, Saheb; Alwis, Imala; Chen, Yunfeng; Tønnesen, Lotte L.; Maiocchi, Sophie; Coulter, Brianna; Calkin, Anna C.; Felner, Eric I.; Cohen, Neale; Yuan, Yuping; Schoenwaelder, Simone M.; Cooper, Mark E.; Zhu, Cheng; Jackson, Shaun P.

(2018), Nat Commun, 9(1), 1087

DOI: 10.1038/s41467-018-03430-6

Regulation of platelet activation and thrombus formation by reactive oxygen species

Qiao, Jianlin; Arthur, Jane F.; Gardiner, Elizabeth E.; Andrews, Robert K.; Zeng, Lingyu; Xu, Kailin

(2018), Redox Biol, 14, 126-130

DOI: 10.1016/j.redox.2017.08.021

EPHB2 regulates platelet activation

Berndt, Michael C.; Andrews, Robert K.

(2018), Blood, 132(19), 2002-2004

DOI: 10.1182/blood-2018-09-876086

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