Research publications | Alfred Health

Oral azacitidine (CC-486) in combination with lenalidomide and dexamethasone in advanced, lenalidomide-refractory multiple myeloma (ROAR study)

Kalff, Anna; Khong, Tiffany; Mithraprabhu, Sridurga; Bergin, Krystal; Reynolds, John; Bowen, Kathryn M.; Thakurta, Anjan; Guzman, Roberto; Wang, Maria; Couto, Suzana; Ren, Yan; Spencer, Andrew

(2019), LEUKEMIA LYMPHOMA, 60(9), 2143-2151.

DOI: 10.1080/10428194.2019.1571201

Fibrinolysis Shutdown in Trauma: Historical Review and Clinical Implications

Moore, Hunter B.; Moore, Ernest E.; Neal, Matthew D.; Sheppard, Forest R.; Kornblith, Lucy Z.; Draxler, Dominik F.; Walsh, Mark; Medcalf, Robert L.; Cohen, Mitch J.; Cotton, Bryan A.; Thomas, Scott G.; Leeper, Christine M.; Gaines, Barbara A.; Sauaia, Angela

(2019), ANESTH ANALG, 129(3), 762-773.

DOI: 10.1213/ANE.0000000000004234

Global coagulation assays in patients with multiple myeloma and monoclonal gammopathy of unknown significance

Lim, Hui Yin; Brook, Rowena; Krishnamoorthi, Brintha; Tacey, Mark; Leung, Teresa; Donnan, Geoffrey; Nandurkar, Harshal; Ho, Prahlad

(2019), THROMB RES, (183), 45-48.

DOI: 10.1016/j.thromres.2019.10.017

SerpinB2 deficiency in mice reduces bleeding times via dysregulated platelet activation

Schroder, Wayne A.; Le, Thuy T.; Gardner, Joy; Andrews, Robert K.; Gardiner, Elizabeth E.; Callaway, Leonie; Suhrbier, Andreas

(2019), PLATELETS, 30(5), 658-663.

DOI: 10.1080/09537104.2018.1535702

PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia

McRae, Helen M.; Garnham, Alexandra L.; Hu, Yifang; Witkowski, Matthew T.; Corbett, Mark A.; Dixon, Mathew P.; May, Rose E.; Sheikh, Bilal N.; Chiang, William; Kueh, Andrew J.; Nguyen, Tan A.; Man, Kevin; Gloury, Renee; Aubrey, Brandon J.; Policheni, Antonia; Di Rago, Ladina; Alexander, Warren S.; Gray, Daniel H.D.; Strasser, Andreas; Hawkins, Edwin D.; Wilcox, Stephen; Gécz, Jozef; Kallies, Axel; McCormack, Matthew P.; Smyth, Gordon K.; Voss, Anne K.; Thomas, Tim

(2019), BLOOD, 133(16), 1729-1741.

DOI: 10.1182/blood-2018-07-860726

A comparison of global coagulation assays between normal controls and patients with thrombocytopenia

Lim, Hui Yin; Leung, Patrick; Manitta, Vanessa; Nandurkar, Harshal; Ho, Prahlad

(2019), INT J LAB HEMATOL, 41(2), 184-191.

DOI: 10.1111/ijlh.12941

Platelet protein disulfide isomerase promotes glycoprotein ib&-mediated platelet-neutrophil interactions under thromboinflammatory conditions

Li, Jing; Kim, Kyungho; Jeong, Si Yeon; Chiu, Joyce; Xiong, Bei; Petukhov, Pavel A.; Dai, Xiangrong; Li, Xiaoyi; Andrews, Robert K.; Du, Xiaoping; Hogg, Philip J.; Cho, Jaehyung

(2019), CIRCULATION, 139(10), 1300-1319.

DOI: 10.1161/CIRCULATIONAHA.118.036323

Hemopoietic Cell Kinase amplification with Protein Tyrosine Phosphatase Receptor T depletion leads to polycythemia, aberrant marrow erythoid maturation, and splenomegaly

Ku, Matthew; MacKinnon, Ruth N.; Wall, Meaghan; Narayan, Nisha; Walkley, Carl; Cheng, Heung Chin; Campbell, Lynda J.; Purton, Louise E.; Nandurkar, Harshal

(2019), SCI REP-UK, 9(1), 7050

DOI: 10.1038/s41598-019-43373-6

Phase 2 study of all-oral ixazomib, cyclophosphamide and low-dose dexamethasone for relapsed/refractory multiple myeloma

Kumar, Shaji K.; Grzasko, Norbert; Delimpasi, Sosana; Jedrzejczak, Wieslaw W.; Grosicki, Sebastian; Kyrtsonis, Marie Christine; Spencer, Andrew; Gupta, Neeraj; Teng, Zhaoyang; Byrne, Catriona; Labotka, Richard; Dimopoulos, Meletios A.

(2019), BRIT J HAEMATOL, 184(4), 536-546.

DOI: 10.1111/bjh.15679

Tranexamic acid modulates the immune response and reduces postsurgical infection rates

Draxler, Dominik F.; Yep, Kah; Hanafi, Gryselda; Winton, Anoushka; Daglas, Maria; Ho, Heidi; Sashindranath, Maithili; Wutzlhofer, Lisa M.; Forbes, Andrew; Goncalves, Isaac; Tran, Huyen A.; Wallace, Sophia; Plebanski, Magdalena; Myles, Paul S.; Medcalf, Robert L.

(2019), Blood Adv, 3(10), 1598-1609.

DOI: 10.1182/bloodadvances.2019000092

Tranexamic acid modulates the cellular immune profile after traumatic brain injury in mice without hyperfibrinolysis

Draxler, Dominik F.; Daglas, Maria; Fernando, Anushka; Hanafi, Gryselda; McCutcheon, Fiona; Ho, Heidi; Galle, Adam; Gregory, Julia; Larsson, Pia; Keragala, Charithani; Wright, David K.; Tavancheh, Elnaz; Au, Amanda E.; Niego, Be'eri; Wilson, Kirsty; Plebanski, Magdalena; Sashindranath, Maithili; Medcalf, Robert L.

(2019), J THROMB HAEMOST, 17(12), 2174-2187.

DOI: 10.1111/jth.14603

Shared roles for Scl and Lyl1 in murine platelet production and function

Chiu, Sung K.; Orive, Stephanie L.; Moon, Mitchell J.; Saw, Jesslyn; Ellis, Sarah; Kile, Benjamin T.; Huang, Yizhou; Chacon, Diego; Pimanda, John E.; Beck, Dominik; Hamilton, Justin R.; Tremblay, Cedric S.; Curtis, David J.

(2019), BLOOD, 134(10), 826-835.

DOI: 10.1182/blood.2019896175

Antiphospholipid syndrome: a clinical review

Mezhov, Veronica; Segan, Julian D.; Tran, Huyen; Cicuttini, Flavia M.

(2019), MED J AUSTRALIA, 211(4), 184-188.

DOI: 10.5694/mja2.50262

T-PA suppresses the immune response and aggravates neurological deficit in a murine model of ischemic stroke

Draxler, Dominik F.; Lee, Felix; Ho, Heidi; Keragala, Charithani B.; Medcalf, Robert L.; Niego, Be'eri

(2019), FRONT IMMUNOL, 10, MAR

DOI: 10.3389/fimmu.2019.00591

Shear-Dependent Platelet Aggregation

Rana, Akshita; Westein, Erik; Niego, Be'eri; Hagemeyer, Christoph E.

(2019), Front Cardiovasc Med, 6, 141

DOI: 10.3389/fcvm.2019.00141

Novel stenotic microchannels to study thrombus formation in shear gradients

Lui, Mathew; Gardiner, Elizabeth E.; Arthur, Jane F.; Pinar, Isaac; Lee, Woei Ming; Ryan, Kris; Carberry, Josie; Andrews, Robert K.

(2019), INT J MOL SCI, 20(12), 2967

DOI: 10.3390/ijms20122967

Corrupted DNA-binding specificity and ectopic transcription underpin dominant neomorphic mutations in KLF/SP transcription factors

Ilsley, Melissa D.; Huang, Stephen; Magor, Graham W.; Landsberg, Michael J.; Gillinder, Kevin R.; Perkins, Andrew C.

(2019), BMC GENOMICS, 20(1), 417

DOI: 10.1186/s12864-019-5805-z

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Iacobucci, Ilaria; Wen, Ji; Meggendorfer, Manja; Choi, John K.; Shi, Lei; Pounds, Stanley B.; Carmichael, Catherine L.; Masih, Katherine E.; Morris, Sarah M.; Lindsley, R. Coleman; Janke, Laura J.; Alexander, Thomas B.; Song, Guangchun; Qu, Chunxu; Li, Yongjin; Payne-Turner, Debbie; Tomizawa, Daisuke; Kiyokawa, Nobutaka; Valentine, Marcus; Valentine, Virginia; Basso, Giuseppe; Locatelli, Franco; Enemark, Eric J.; Kham, Shirley K.Y.; Yeoh, Allen E.J.; Ma, Xiaotu; Zhou, Xin; Sioson, Edgar; Rusch, Michael; Ries, Rhonda E.; Stieglitz, Elliot; Hunger, Stephen P.; Wei, Andrew H.; To, L. Bik; Lewis, Ian D.; D’Andrea, Richard J.; Kile, Benjamin T.; Brown, Anna L.; Scott, Hamish S.; Hahn, Christopher N.; Marlton, Paula; Pei, Deqing; Cheng, Cheng; Loh, Mignon L.; Ebert, Benjamin L.; Meshinchi, Soheil; Haferlach, Torsten; Mullighan, Charles G.

(2019), NAT GENET, 51(4), 694-704.

DOI: 10.1038/s41588-019-0375-1

Meta-analysis of Grainyhead-like dependent transcriptional networks

Mathiyalagan, Nishanthi; Miles, Lee B.; Anderson, Peter J.; Wilanowski, Tomasz; Grills, Brian L.; McDonald, Stuart J.; Keightley, M. Cristina; Charzynska, Agata; Dabrowski, Michal; Dworkin, Sebastian

(2019), GENES-BASEL, 10(11, 876

DOI: 10.3390/genes10110876

Toll-like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2

Liu, You Dong; Yu, Liang; Ying, Le; Balic, Jesse; Gao, Hugh; Deng, Nian Tao; West, Alison; Yan, Feng; Ji, Cheng Bo; Gough, Daniel; Tan, Patrick; Jenkins, Brendan J.; Li, Ji Kun

(2019), INT J CANCER, 144(12), 3056-3069.

DOI: 10.1002/ijc.32060