Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Defective lysosome reformation during autophagy causes skeletal muscle disease

McGrath MJ, Eramo MJ, Gurung R, Sriratana A, Gehrig SM, Lynch GS, Lourdes SR, Koentgen F, Feeney SJ, Lazarou M, McLean CA, Mitchell CA

(2021), J Clin Invest, 131(1), e135124

DOI: 10.1172/JCI135124

Excellent outcomes of transformed lymphomas in the rituximab era without autologous stem cell transplantation: an Australian, single-centre experience

Tedjaseputra A, Gilbertson M, Low M, Fedele PL, Kumar B, Simpson I, Grigoriadis G, Shortt J, Opat S, Gregory GP

(2021), Intern Med J, 51(11), 1825-34

DOI: 10.1111/imj.14965

The transcription factor IRF4 represses proapoptotic BMF and BIM to licence multiple myeloma survival

Fedele PL, Liao Y, Gong JN, Yao Y, van Delft MF, Low MSY, Tai L, Herold MJ, Jackson JT, Teh CE, Tan T, O'Reilly LA, Tellier J, Grigoriadis G, Huang DCS, Shi W, Nutt SL, Willis SN

(2021), Leukemia, 335(7), 2114-8

DOI: 10.1038/s41375-020-01078-0

Safety and efficacy of talacotuzumab plus decitabine or decitabine alone in patients with acute myeloid leukemia not eligible for chemotherapy: results from a multicenter, randomized, phase 2/3 study

Montesinos P, Roboz GJ, Bulabois CE, Subklewe M, Platzbecker U, Ofran Y, Papayannidis C, Wierzbowska A, Shin HJ, Doronin V, Deneberg S, Yeh SP, Ozcan MA, Knapper S, Cortes J, Pollyea DA, Ossenkoppele G, Giralt S, Döhner H, Heuser M, Xiu L, Singh I, Huang F, Larsen JS, Wei AH

(2021), Leukemia, 35(1), 62-74

DOI: 10.1038/s41375-020-0773-5

Venetoclax induces rapid elimination of NPM1 mutant measurable residual disease in combination with low-intensity chemotherapy in acute myeloid leukaemia

Tiong IS, Dillon R, Ivey A, Teh TC, Nguyen P, Cummings N, Taussig DC, Latif AL, Potter NE, Runglall M, Russell NH, Raj K, Schwarer AP, Fong CY, Grigg AP, Wei AH

(2021), BRIT J HAEMATOL, 192(6), 1026-30

DOI: 10.1111/bjh.16722

Venetoclax with azacitidine or decitabine in patients with newly diagnosed acute myeloid leukemia: Long term follow-up from a phase 1b study

Pollyea DA, Pratz K, Letai A, Jonas BA, Wei AH, Pullarkat V, Konopleva M, Thirman MJ, Arellano M, Becker PS, Chyla B, Hong WJ, Jiang Q, Potluri J, DiNardo CD

(2021), Am J Hematol, 96(2), 208-17

DOI: 10.1002/ajh.26039

Double trouble or a silver lining? A case report of two patients with NPM1-mutated donor-derived acute myeloid leukemia (AML)

Loh JBE, Walker P, Avery S, Patil S, Spencer A, Wei A, Fleming S

(2021), LEUKEMIA LYMPHOMA, 62(2), 489-91

DOI: 10.1080/10428194.2020.1832663

Evaluation of EuroFlow minimal residual disease measurement and donor chimerism monitoring following tandem auto-allogeneic transplantation for multiple myeloma

Tan JLC, Das T, Kliman D, Muirhead J, Gorniak M, Kalff A, Walker P, Spencer A

(2021), BONE MARROW TRANSPL, 56(5), 1116-25

DOI: 10.1038/s41409-020-01148-y

Phase II trial of single-agent panobinostat consolidation improves responses after sub-optimal transplant outcomes in multiple myeloma

Mithraprabhu S, Kalff A, Gartlan KH, Savvidou I, Khong T, Ramachandran M, Cooke RE, Bowen K, Hill GR, Reynolds J, Spencer A

(2021), BRIT J HAEMATOL, 193(1), 160-70

DOI: 10.1111/bjh.17080

Long-Term Immune Function Following Splenic Artery Embolisation for Blunt Abdominal Trauma

Lukies M, Kavnoudias H, Zia A, Lee R, Bosco JJ, Joseph T, Clements W

(2021), CARDIOVASC INTER RAD, 44(1), 167-9

DOI: 10.1007/s00270-020-02627-x

Beyond monogenetic rare variants: tackling the low rate of genetic diagnoses in predominantly antibody deficiency

Edwards ESJ, Bosco JJ, Ojaimi S, O'Hehir RE, van Zelm MC

(2021), Cell Mol Immunol, 18(3), 588-603

DOI: 10.1038/s41423-020-00520-8

Antimicrobial resistance in the Pacific Island countries and territories.

Loftus M, Stewardson A, Naidu R, Coghlan B, Jenney A, Kepas J, Lavu E, Munamua A, Peel T, Sahai V, Tekoaua R, Tudravu L, Zinihite J, Cheng A, Rafai E, Peleg A

(2020), BMJ Glob Health, 5(4), e002418

DOI: 10.1136/bmjgh-2020-002418

Prevalence of hyperglycaemia without previously recognised diabetes mellitus in the Emergency Department and subsequent management - A retrospective cross-sectional study

Epa DS, Ng E, Schneider HG, Nagalingam V, Bach LA, Sztal-Mazer S

(2020), Intern Med J, 50(11), 1397-1403

DOI: 10.1111/imj.14720

Arterio-VENouS Intra Subject agreement for blood gases within intensive care: The AVENSIS study

Nanjayya VB, McCracken P, Vallance S, Board J, Kelly PJ, Schneider HG, Pilcher D, Garner DJ

(2020), Journal of the Intensive Care Society, 21(1), 64-71

DOI: 10.1177/1751143719840259

Data Sets for the Reporting of Tumors of the Central Nervous System: Recommendations From The International Collaboration on Cancer Reporting

Louis DN, Wesseling P, Brandner S, Brat DJ, Ellison DW, Giangaspero F, Hattab EM, Hawkins C, Judge MJ, Kleinschmidt-DeMasters B, Komori T, McLean C, Paulus W, Perry A, Reifenberger G, Weller M, Rous B

(2020), Arch Pathol Lab Med, 144(2), 196-206

DOI: 10.5858/arpa.2018-0565-OA

Neurotrophic interactions between neurons and astrocytes following AAV1-Rheb(S16H) transduction in the hippocampus in vivo

Jeon MT, Moon GJ, Kim S, Choi M, Oh YS, Kim DW, Kim HJ, Lee KJ, Choe Y, Ha CM, Jang IS, Nakamura M, McLean C, Chung WS, Shin WH, Lee SG, Kim SR

(2020), BRIT J PHARMACOL, 177(3), 668-86

DOI: 10.1111/bph.14882

Acral lentiginous melanoma: differences in survival compared with other subtypes.

Howard MD, Xie C, Wee E, Wolfe R, McLean CA, Kelly JW, Pan Y

(2020), Brit J Dermatol, 182(4), 1056-7

DOI: 10.1111/bjd.18620

Characterising the brain metalloproteome in Down syndrome patients with concomitant Alzheimer's pathology

Malakooti N , Roberts B , Pritchard MA , Volitakis I , Kim RC , Lott IT , McLean CA , Finkelstein DI , Adlard PA

(2020), Metallomics, 12(1), 114-32

DOI: 10.1039/c9mt00196d

Regional iron distribution and soluble ferroprotein profiles in the healthy human brain

McAllum EJ, Hare DJ, Volitakis I, McLean CA, Bush AI, Finkelstein DI, Roberts BR

(2020), Prog Neurobiol, 186, 101744

DOI: 10.1016/j.pneurobio.2019.101744

The anatomic distribution of cutaneous melanoma: A detailed study of 5141 lesions

Wee E, Wolfe R, Mclean C, Kelly JW, Pan Y

(2020), Australas J Dermatol, 61(2), 125-33

DOI: 10.1111/ajd.13223

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