Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Genomic Risk Prediction for Breast Cancer in Older Women

Lacaze P, Bakshi A, Riaz M, Orchard SG, Tiller J, Neumann JT, Carr PR, Joshi AD, Cao Y, Warner ET, Manning A, Nguyen-Dumont T, Southey MC, Milne RL, Ford L, Sebra R, Schadt E, Gately L, Gibbs P, Thompson BA, Macrae FA, James P, Winship I, McLean C, Zalcberg JR, Woods RL, Chan AT, Murray AM, McNeil JJ

(2021), Cancers, 13(14), 3533

DOI: 10.3390/cancers13143533

Creutzfeldt-Jakob disease surveillance in Australia: update to 31 December 2020

Stehmann C, Senesi M, Sarros S, McGlade A, Lewis V, Simpson M, Klug G, McLean CA, Masters CL, Collins SJ

(2021), Communicable Diseases Intelligence, 45

DOI: 10.33321/cdi.2021.45.38

Immunohistochemical evidence of P2X7R, P2X4R and CaMKK2 in pyramidal neurons of frontal cortex does not align with Alzheimer's disease

Gaff J, Jackaman C, Papadimitriou J, Waters S, McLean C, Price P

(2021), Exp Mol Pathol, 120, 104636

DOI: 10.1016/j.yexmp.2021.104636

INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer

Rodgers SJ, Ooms LM, Oorschot VMJ, Schittenhelm RB, Nguyen EV, Hamila SA, Rynkiewicz N, Gurung R, Eramo MJ, Sriratana A, Fedele CG, Caramia F, Loi S, Kerr G, Abud HE, Ramm G, Papa A, Ellisdon AM, Daly RJ, McLean CA, Mitchell CA

(2021), Nat Commun, 12(1), 3140

DOI: 10.1038/s41467-021-23241-6

Transcriptional signature in microglia associated with Aβ plaque phagocytosis

Grubman A, Choo XY, Chew G, Ouyang JF, Sun G, Croft NP, Rossello FJ, Simmons R, Buckberry S, Landin DV, Pflueger J, Vandekolk TH, Abay Z, Zhou Y, Liu X, Chen J, Larcombe M, Haynes JM, McLean C, Williams S, Chai SY, Wilson T, Lister R, Pouton CW, Purcell AW, Rackham OJL, Petretto E, Polo JM

(2021), Nat Commun, 12(1), 3015

DOI: 10.1038/s41467-021-23111-1

Primary leptomeningeal low-grade Schwann cell neoplasm

Vallat W, Antony S, Patel S, McLean C

(2021), BMJ Case Reports, 14(11), e244440

DOI: 10.1136/bcr-2021-244440

Comparing amyloid-β plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease

Chen CD, Joseph-Mathurin N, Sinha N, Zhou A, Li Y, Friedrichsen K, McCullough A, Franklin EE, Hornbeck R, Gordon B, Sharma V, Cruchaga C, Goate A, Karch C, McDade E, Xiong C, Bateman RJ, Ghetti B, Ringman JM, Chhatwal J, Masters CL, McLean C, Lashley T, Su Y, Koeppe R, Jack C, Klunk WE, Morris JC, Perrin RJ, Cairns NJ, Benzinger TLS

(2021), Acta Neuropathol, 142(4), 689-706

DOI: 10.1007/s00401-021-02342-y

Low prevalence of amyloid and tau pathology in drug-resistant temporal lobe epilepsy

Silva JC, Vivash L, Malpas CB, Hao Y, McLean C, Chen Z, O'Brien TJ, Jones NC, Kwan P

(2021), Epilepsia, 62(12), 3058-67

DOI: 10.1111/epi.17086

Characterization of brain-derived extracellular vesicle lipids in Alzheimer's disease

Su H, Rustam YH, Masters CL, Makalic E, McLean CA, Hill AF, Barnham KJ, Reid GE, Vella LJ

(2021), J Extracell Vesicles, 10(7), e12089

DOI: 10.1002/jev2.12089

Citrullination of Amyloid-β Peptides in Alzheimer's Disease

Mukherjee S, Perez KA, Dubois C, Nisbet RM, Li QX, Varghese S, Jin L, Birchall I, Streltsov VA, Vella LJ, McLean C, Barham KJ, Roberts BR, Masters CL

(2021), ACS Chem Neurosci, 12(19), 3719-32

DOI: 10.1021/acschemneuro.1c00474

Differential NPY-Y1 Receptor Density in the Motor Cortex of ALS Patients and Familial Model of ALS

Clark CM, Clark RM, Hoyle JA, Chuckowree JA, McLean CA, Dickson TC

(2021), Brain Sci, 11(8), 969

DOI: 10.3390/brainsci11080969

Sex-dependent effects of amyloid precursor-like protein 2 in the SOD1-G37R transgenic mouse model of MND

Truong PH, Crouch PJ, Hilton JBW, McLean CA, Cappai R, Ciccotosto GD

(2021), Cell Mol Life Sci, 78(19-20), 6605-30

DOI: 10.1007/s00018-021-03924-5

Peeling back the onion layers': the challenge of HIV-associated multicentric Castleman's disease

Liu FF, Hall V, Cronin KM, Nair AP, Mclean CA, Hoy JF

(2021), AIDS, 35(1), 159-61

DOI: 10.1097/QAD.0000000000002705

Evaluation of FGFR targeting in breast cancer through interrogation of patient-derived models

Chew NJ, Lim Kam Sian TCC, Nguyen EV, Shin SY, Yang J, Hui MN, Deng N, McLean CA, Welm AL, Lim E, Gregory P, Nottle T, Lang T, Vereker M, Richardson G, Kerr G, Micati D, Jardé T, Abud HE, Lee RS, Swarbrick A, Daly RJ

(2021), Breast Cancer Res, 23(1), 82

DOI: 10.1186/s13058-021-01461-4

Biallelic hypomorphic variants in ALDH1A2 cause a novel lethal human multiple congenital anomaly syndrome encompassing diaphragmatic, pulmonary, and cardiovascular defects

Beecroft SJ, Ayala M, McGillivray G, Nanda V, Agolini E, Novelli A, Digilio MC, Dotta A, Carrozzo R, Clayton J, Gaffney L, McLean CA, Ng J, Laing NG, Matteson P, Millonig J, Ravenscroft G

(2021), Hum Mutat, 42(5), 506-19

DOI: 10.1002/humu.24179

Misclassification of calcium status in end-stage kidney disease using albumin-adjusted calcium levels

Law MM, Smith JD, Schneider HG, Wilson S

(2021), Nephrology, 26(9), 725-32

DOI: 10.1111/nep.13910

Report of the Survey Conducted by RCPAQAP on Current Practices for Beta-Migrating Paraprotein Reporting

Smith JD, Wijeratne N, Schneider HG, de Malmanche T, Hissaria P, Toit SD, Chiu W, Boyder C, Morison IM, Tseng A, Glegg K, Wienholt L, Mollee P

(2021), The Clinical Biochemist Reviews, 42(1), 11-6

DOI: 10.33176/AACB-21-00001

Aetiologies and factors associated with poor clinical outcomes in rhabdomyolysis: a retrospective cohort study in an Australian trauma centre

Khu YL, Lewis B, Blackshaw L, Tan SMQ, Bayfield A, Schneider HG, Liew D, Aung AK

(2021), Intern Med J, 51(2), 264-7

DOI: 10.1111/imj.15183

Urine toxicology screening by liquid chromatography time-of-flight mass spectrometry in a quaternary hospital setting

Pope JD, Black MJ, Drummer OH, Schneider HG

(2021), Clin Biochem, 95, 66-72

DOI: 10.1016/j.clinbiochem.2021.05.004

Myeloid somatic mutation panel testing in myeloproliferative neoplasms

Ross DM, Thomson C, Hamad N, Lane SW, Manos K, Grigg AP, Guo B, Erber WN, Scott A, Viiala N, Chee L, Latimer M, Tate C, Grove C, Perkins AC, Blombery P

(2021), Pathology, 53(3), 339-48

DOI: 10.1016/j.pathol.2021.01.003

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