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Our clinical trial portfolio is one of the largest in the country. We have more than 700 clinical trials open across 30 clinical units.

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627 clinical trials found
Clinical trials

PEPSTEP

Perampanel for the prevention of post-stroke epilepsy: a pilot phase II randomised controlled trial (ACTRN12618001984280)

Currently recruiting

PERFORM-CPR

Personalised Exercise Rehabilitation FOR people with multimorbidity (ACTRN12624001191583)

Many people in Australia are living with multiple long-term health conditions such as heart and lung disease, diabetes, arthritis, stroke, depression, and cancer. Exercise-based rehabilitation may help people with chronic conditions improve their physical function, symptoms and quality of life and help them spend less time in the hospital. However, until now there have been few exercise options for people living with multiple long-term health conditions. We are now conducting a study to see if a personalised rehabilitation program (PERFORM trial), which includes exercises and education sessions, can improve wellbeing and physical function better than usual care in people with multiple long-term health conditions.
Currently recruiting

Perseus

A Phase 3 Study Comparing Daratumumab, VELCADE [bortezomib], Lenalidomide, and Dexamethasone [D-VRd] vs VELCADE, Lenalidomide, and Dexamethasone [VRd] in Subjects with Previously Untreated Multiple Myeloma who are Eligible for High-dose Therapy. (NCT03710603)

No longer recruiting

PERSONAL

PERsonalised Selection Of medication for Newly diagnosed Adult epiLepsy (ACTRN12623000209695)

Currently recruiting

PESTO

A Prospective multicentre, phase 2b randomised controlled double-blind trial, to determine the safety and efficacy of perispinal etanercept on quality of life at 28 days post treatment. (ACTRN12620001011976)

Currently recruiting

PETRANHA

A Multi-arm, Open-label Phase I/IIa Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of AZD5305 in Combination with New Hormonal Agents in Patients with Metastatic Prostate Cancer (PETRANHA) (NCT05367440)

Currently recruiting

Pfizer B7981080

A PHASE 3 RANDOMIZED, DOUBLE-BLIND, 52-WEEK PLACEBOCONTROLLED MULTI-CENTER STUDY WITH A DOUBLE-BLIND 52-WEEK EXTENSION PERIOD WITH RANDOMIZED DOSE UP/DOSE DOWN TITRATION INVESTIGATING THE EFFICACY, SAFETY, AND TOLERABILITY OF RITLECITINIB IN ADULT PARTICIPANTS WITH NONSEGMENTAL VITILIGO (NCT06072183)

No longer recruiting

PFOX

PFOX: Pulmonary Fibrosis Ambulatory Oxygen Trial (NCT03737409)

Currently recruiting

Pilot WLM

A phase 2 randomised, open-label trial of maintenance of weight loss with alternate-weekly incretin medication dosing (ACTRN12625000609459)

Currently recruiting

PIPOZA

Clonal Dynamics of Chronic Lymphocytic Leukaemia Treated with Pirtobrutinib after Previous Treatment with Zanubrutinib (NCT06812715)

This is a multicentre single-arm prospective phase II trial evaluating pirtobrutinib in the treatment of relapsed/refractory (R/R) Chronic Lymphocytic Leukaemia (CLL) patients who have previously received zanubrutinib, and to specifically evaluate Bruton Tyrosine Kinase (BTK) mutational status (clonal dynamics) before, during and after treatment with pirtobrutinib.
Currently recruiting

PiVET-ED

A prospective, randomized, single-blinded, sham controlled study of Pelvic Vein Embolization (PVE) for treatment of erectile dysfunction (ED) (ACTRN12620001023943)

Currently recruiting

PoCeMR

Development of Clinical Utility for Point of Care MRI (Trial Not Registered)

Currently recruiting

POIESIS

A Phase 3, Randomized, Double-blind, Add-on Study Evaluating the Safety and Efficacy of Navtemadlin Plus Ruxolitinib vs Placebo Plus Ruxolitinib in JAK Inhibitor-Naïve Patients with Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib (NCT06479135)

Currently recruiting

POLARIS-3

A Single-Arm Registrational Phase III Study of Olverembatinib in the Treatment of Patients with SDH-Deficient Gastrointestinal Stromal Tumor [POLARIS-3] (NCT06640361)

Currently recruiting

POLARIS1

A Global Multicenter, Open Label, Randomized Phase 3 Registrational Study of Olverembatinib Combined with Chemotherapy Versus Imatinib Combined with Chemotherapy in Patients with Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL). (NCT06051409)

Currently recruiting

PORTHOS Study

A Prospective angiOtensin vs. noRadrenaline Trial for Hypotension management to reduce length Of hospital stay in Cardiac Surgery (the PORTHOS study) (ACTRN12623000848606p)

Currently recruiting

Portico IDE

Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial (PORTICO)

The PORTICO pivotal IDE trial is a prospective, multi-center, randomized, controlled clinical investigation study designed to evaluate the safety and effectiveness of the SJM Portico Transcatheter Heart Valve and Delivery Systems (Portico) via transfemoral and alternative delivery methods in high-risk and extreme-risk patients.

No longer recruiting

Portico NG

Portico NG - Evaluation of the Navitor Transcatheter Aortic Valve in High and Extreme Risk Patients with Symptomatic Severe Aortic Stenosis

The primary objective of this clinical study is to evaluate the acute safety and effectiveness of the Navitor Transcatheter Aortic Heart Valve as assessed by the rate of all-cause mortality at 30 days and the rate of moderate or greater paravalvular leak at 30 days. The results from this study will be descriptively compared to the data from the first-generation Portico Transcatheter Aortic Heart Valve and commercially available TAVI devices studied in the same patient population (e.g. high and extreme surgical risk).

No longer recruiting

POST-ETERNAL

Extending the time window for Tenecteplase by Effective RecanalizatioN of bAsilar artery occLusion in patients with POSTerior circulation stroke (NCT05105633)

Currently recruiting

POTAT

A Pilot Study of Post Operative Iron Infusion for the Treatment of Anaemia in trauma Patients (ACTRN12624000410550)

No longer recruiting
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