Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Clinical benefits of eplerenone in patients with systolic heart failure and mild symptoms when initiated shortly after hospital discharge: analysis from the EMPHASIS-HF trial

Girerd N, Collier T, Pocock S, Krum H, McMurray JJ, Swedberg K, Van Veldhuisen DJ, Vincent J, Pitt B, Zannad F

(2015), Eur Heart J, 36(34), 2310-7

Digoxin withdrawal worsens clinical status in stable patients with heart failure receiving optimal contemporaneous therapy--a randomized controlled trial

Hopper I, Skiba M, von Lueder TG, Watanabe M, Funston R, Tonkin A, Krum H

(2015), J Card Fail, 21(9), 779-81

New medical therapies for heart failure

von Lueder TG, Krum H

(2015), Nat Rev Cardiol, 12(12), 730-40

Increased risk of stroke with darbepoetin alfa in anaemic heart failure patients with diabetes and chronic kidney disease

Bello NA, Lewis EF, Desai AS, Anand IS, Krum H, McMurray JJ, Olson K, Solomon SD, Swedberg K, van Veldhuisen DJ, Young JB, Pfeffer MA

(2015), Eur J Heart Fail, 17(11), 1201-7

The Aliskiren Trial to Minimize OutcomeS in Patients with HEart failure trial (ATMOSPHERE): revised statistical analysis plan and baseline characteristics

Krum H, McMurray JJ, Abraham WT, Dickstein K, KØber L, Desai AS, Solomon SD, Chiang Y, Gimpelewicz C, Reimund B, Ali MA, Tarnesby G, Massie BM; ATMOSPHERE Committees and Investigators

(2015), Eur J Heart Fail, 17(10), 1075-83

Nurse-led titration of angiotensin converting enzyme inhibitors, beta-adrenergic blocking agents, and angiotensin receptor blockers for people with heart failure with reduced ejection fraction

Driscoll A, Currey J, Tonkin A, Krum H

(2015), Cochrane Database Syst Rev, 12, CD009889

Is operative management of fractures safe in the collocated burn and fracture injury?

Bradshaw L, Wasiak J, Cleland H

(2015), Injury, 46(6), 1145-9

Transfer time to a specialist burn service and influence on burn mortality in Australia and New Zealand: a multi-centre, hospital based retrospective cohort study

Cassidy TJ, Edgar DW, Phillips M, Cameron P, Cleland H, Wood FM; Steering Committee of the ANZBA Burn Registry of Australia and New Zealand

(2015), Burns, 41(4), 735-41

Clinical differences between major burns patients deemed survivable and non-survivable on admission

Mahar PD, Wasiak J, Cleland H, Paul E, Loke SY, Fong HC, Kirby JC

(2015), Injury, 46(5), 870-3

Effective use of Biobrane as a temporary wound dressing prior to definitive split skin graft in the treatment of severe burn: a retrospective analysis

Tan H, Wasiak J, Paul E, Cleland H

(2015), Burns, 41(5), 969-76

Use of clotted human plasma and aprotinin in skin tissue engineering: a novel approach to engineering composite skin on a porous scaffold

Paul M, Kaur P, Herson M, Cheshire P, Cleland H, Akbarzadeh S

(2015), Tissue Eng Part C Methods, 21(10), 1098-104

Mortality and length of stay in elderly toxic epidermal necrolysis patients

Mahar PD, Wasiak J, Gin D, Cleland H, Watters DA

(2015), Australas J Dermatol, 56(3), 233-4

Long term outcomes data for the Burns Registry of Australia and New Zealand: is it feasible?

Gabbe BJ, Cleland H, Watterson DM, Schrale R, McRae S, Parker C, Taggart S, Edgar DW; Burns Registry of Australia, New Zealand Long Term Outcomes Working Party

(2015), Burns, 41(8), 1732-40

Activation of the erythroid K-Cl cotransporter Kcc1 enhances sickle cell disease pathology in a humanized mouse model

Brown FC, Conway AJ, Cerruti L, Collinge JE, McLean C, Wiley JS, Kile BT, Jane SM, Curtis DJ

(2015), Blood, 126(26), 2863-70

Tools for translational epigenetic studies involving formalin-fixed paraffin-embedded human tissue: applying the Infinium HumanMethyation450 Beadchip assay to large population-based studies

Wong EM, Joo JE, McLean CA, Baglietto L, English DR, Severi G, Hopper JL, Milne RL, FitzGerald LM, Giles GG, Southey MC

(2015), BMC Res Notes, 8, 543

Rab1-dependent ER–Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS

Soo KY, Halloran M, Sundaramoorthy V, Parakh S, Toth RP, Southam KA, McLean CA, Lock P, King A, Farg MA, Atkin JD

(2015), Acta Neuropathol, 130(5), 679-97

The inositol polyphosphate 5-phosphatase PIPP regulates AKT1-dependent breast cancer growth and metastasis

Ooms LM, Binge LC, Davies EM, Rahman P, Conway JR, Gurung R, Ferguson DT, Papa A, Fedele CG, Vieusseux JL, Chai RC, Koentgen F, Price JT, Tiganis T, Timpson P, McLean CA, Mitchell CA

(2015), Cancer Cell, 28(2), 155-69

Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

Kouri N, Ross OA, Dombroski B, Younkin CS, Serie DJ, Soto-Ortolaza A, Baker M, Finch NC, Yoon H, Kim J, Fujioka S, McLean CA, Ghetti B, Spina S, Cantwell LB, Farlow MR, Grafman J, Huey ED, Ryung Han M, Beecher S, Geller ET, Kretzschmar HA, Roeber S, Gearing M, Juncos JL, Vonsattel JP, Van Deerlin VM, Grossman M, Hurtig HI, Gross RG, Arnold SE, Trojanowski JQ, Lee VM, Wenning GK, White CL, HÖglinger GU, Müller U, Devlin B, Golbe LI, Crook J, Parisi JE, Boeve BF, Josephs KA, Wszolek ZK, Uitti RJ, Graff-Radford NR, Litvan I, Younkin SG, Wang LS, Ertekin-Taner N, Rademakers R, Hakonarsen H, Schellenberg GD, Dickson DW

(2015), Nat Commun, 6, 7247

Is the logopenic-variant of primary progressive aphasia a unitary disorder?

Leyton CE, Hodges JR, McLean CA, Kril JJ, Piguet O, Ballard KJ

(2015), Cortex, 67, 122-33

Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML

Rijal S, Fleming S, Cummings N, Rynkiewicz NK, Ooms LM, Nguyen NY, Teh TC, Avery S, McManus JF, Papenfuss AT, McLean C, Guthridge MA, Mitchell CA, Wei AH

(2015), Blood, 125(18), 2815-24