Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Changing face of care for patients with moderate to severe inflammatory bowel disease: the role of specialist nurses in the governance of anti-TNF prescribing

Connell WR, Samyue T, Gibson PR, Lachal S, Moore GT, Macrae FA, Van Langenberg DR

(2015), Intern Med J, 45(11), 1161-6

Long-term outcomes of colectomy surgery among patients with ulcerative colitis

Brown C, Gibson PR, Hart A, Kaplan GG, Kachroo S, Ding Q, Hautamaki E, Fan T, Black CM, Hu X, Beusterien K

(2015), Springerplus, 4, 573

Phase 1/1B trial of the heat shock protein 90 inhibitor NVP-AUY922 as monotherapy or in combination with bortezomib in patients with relapsed or refractory multiple myeloma

Seggewiss-Bernhardt R, Bargou RC, Goh YT, Stewart AK, Spencer A, Alegre A, Bladé J, Ottmann OG, Fernandez-Ibarra C, Lu H, Pain S, Akimov M, Iyer SP

(2015), Cancer, 121(13), 2185-92

The residual risk of transfusion-transmitted cytomegalovirus infection associated with leucodepleted blood components

Seed CR, Wong J, Polizzotto MN, Faddy H, Keller AJ, Pink J

(2015), Vox Sang, 109(1), 11-7

BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs

Sadler AJ, Rossello FJ, Yu L, Deane JA, Yuan X, Wang D, Irving AT, Kaparakis-Liaskos M, Gantier MP, Ying H, Yim HC, Hartland EL, Notini AJ, de Boer S, White SJ, Mansell A, Liu JP, Watkins DN, Gerondakis S, Williams BR, Xu D

(2015), Proc Natl Acad Sci USA, 112(5), 1535-40

A phase 2 study of the BH3 mimetic BCL2 inhibitor navitoclax (ABT-263) with or without rituximab, in previously untreated B-cell chronic lymphocytic leukemia

Kipps TJ, Eradat H, Grosicki S, Catalano J, Cosolo W, Dyagil IS, Yalamanchili S, Chai A, Sahasranaman S, Punnoose E, Hurst D, Pylypenko H

(2015), Leuk Lymphoma, 56(10), 2826-33

Cytogenetics and long-term survival of patients with refractory or relapsed and refractory multiple myeloma treated with pomalidomide and low-dose dexamethasone

Dimopoulos MA, Weisel KC, Song KW, Delforge M, Karlin L, Goldschmidt H, Moreau P, Banos A, Oriol A, Garderet L, Cavo M, Ivanova V, Alegre A, Martinez-Lopez J, Chen C, Spencer A, Knop S, Bahlis NJ, Renner C, Yu X, Hong K, Sternas L, Jacques C, Zaki MH, San Miguel JF

(2015), Haematologica, 100(10), 1327-33

An analysis of the thromboembolic outcomes of 2472 splenectomized individuals

Dendle C, Spelman T, Sundararajan V, Chunilal S, Woolley I

(2015), Blood, 125(10), 1681-2

An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model

Van Overbeke W, Wongsantichon J, Everaert I, Verhelle A, Zwaenepoel O, Loonchanta A, Burtnick LD, De Ganck A, Hochepied T, Haigh J, Cuvelier C, Derave W, Robinson RC, Gettemans J

(2015), Hum Mol Genet, 24(9), 2492-507

Effects of abacavir administration on structural and functional markers of platelet activation

Trevillyan JM, Arthur JF, Jing J, Andrews RK, Gardiner EE, Hoy JF

(2015), AIDS, 29(17), 2309-13

Imatinib treatment reduces brain injury in a murine model of traumatic brain injury

Su EJ, Fredriksson L, Kanzawa M, Moore S, Folestad E, Stevenson TK, Nilsson I, Sashindranath M, Schielke GP, Warnock M, Ragsdale M, Mann K, Lawrence AL, Medcalf RL, Eriksson U, Murphy GG, Lawrence DA

(2015), Front Cell Neurosci, 9, 385

Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury

Shultz SR, Wright DK, Zheng P, Stuchbery R, Liu SJ, Sashindranath M, Medcalf RL, Johnston LA, Hovens CM, Jones NC, O'Brien TJ

(2015), Brain, 138(Pt 5), 1297-313

Evaluation of gait impairment in mice subjected to craniotomy and traumatic brain injury

Sashindranath M, Daglas M, Medcalf RL

(2015), Behav Brain Res, 286, 33-8

An atypical IgM class platelet cold agglutinin induces GPVI-dependent aggregation of human platelets

Sánchez Guiu IM, Martínez-Martinez I, Martínez C, Navarro-Fernandez J, García-Candel F, Ferrer-Marín F, Vicente V, Watson SP, Andrews RK, Gardiner EE, Lozano ML1, Rivera J

(2015), Thromb Haemost, 114(2), 313-24

MouseMove: an open source program for semi-automated analysis of movement and cognitive testing in rodents

Samson AL, Ju L, Ah Kim H, Zhang SR, Lee JA, Sturgeon SA, Sobey CG, Jackson SP, Schoenwaelder SM

(2015), Sci Rep, 5, 16171

Global regulator MorA affects virulence-associated protease secretion in Pseudomonas aeruginosa PAO1

Ravichandran A, Ramachandran M, Suriyanarayanan T, Wong CC, Swarup S

(2015), PLoS One, 10(4), e0123805

The platelet Fc receptor, FcγRIIa

Qiao J, Al-Tamimi M, Baker RI, Andrews RK, Gardiner EE

(2015), Immunol Rev, 268(1), 241-52

Methods to determine the lagrangian shear experienced by platelets during thrombus growth

Pinar IP, Arthur JF, Andrews RK, Gardiner EE, Ryan K, Carberry J

(2015), PLoS One, 10(12), e0144860

Discovery and SAR of novel pyrazolo[1,5-a]pyrimidines as inhibitors of CDK9

Phillipson LJ, Segal DH, Nero TL, Parker MW, Wan SS, de Silva M, Guthridge MA, Wei AH, Burns CJ

(2015), Bioorg Med Chem, 23(19), 6280-96

Asymmetric cell division during T cell development controls downstream fate

Pham K, Shimoni R, Charnley M, Ludford-Menting MJ, Hawkins ED, Ramsbottom K, Oliaro J, Izon D, Ting SB, Reynolds J, Lythe G, Molina-Paris C, Melichar H, Robey E, Humbert PO, Gu M, Russell SM

(2015), J Cell Biol, 210(6), 933-50

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