Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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The p53 family and VEGF regulation: "it's complicated"

Farhang Ghahremani M, Goossens S, Haigh JJ

(2013), Cell Cycle, 12(9), 1331-2

Effect of ruxolitinib therapy on myelofibrosis-related symptoms and other patient-reported outcomes in COMFORT-I: a randomized, double-blind, placebo-controlled trial

Mesa RA, Gotlib J, Gupta V, Catalano JV, Deininger MW, Shields AL, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH, Hare T, Erickson-Viitanen S, Sun W, Sandor V, Levy RS, Kantarjian HM, Verstovsek S

(2013), J Clin Oncol, 31(10), 1285-92

Differentiating haemostasis from thrombosis for therapeutic benefit

McFadyen JD, Jackson SP

(2013), Thromb Haemost, 110(5), 859-67

LIM-domain-only proteins in cancer

Matthews JM, Lester K, Joseph S, Curtis DJ

(2013), Nat Rev Cancer, 13(2), 111-22

Phosphorylation of serine 779 in fibroblast growth factor receptor 1 and 2 by protein kinase C(epsilon) regulates Ras/mitogen-activated protein kinase signaling and neuronal differentiation

Lonic A, Powell JA, Kong Y, Thomas D, Holien JK, Truong N, Parker MW, Guthridge MA

(2013), J Biol Chem, 288(21), 14874-85

Endothelial VEGF sculpts cortical cytoarchitecture

Li S, Haigh K, Haigh JJ, Vasudevan A

(2013), J Neurosci, 33(37), 14809-15

MEK inhibitors as a chemotherapeutic intervention in multiple myeloma

Chang-Yew Leow C, Gerondakis S, Spencer A

(2013), Blood Cancer J, 3, e105

The PAR1 antagonist, SCH79797, alters platelet morphology and function independently of PARs

Lee H, Hamilton JR

(2013), Thromb Haemost, 109(1), 164-7

Adhesion maturation of neutrophils on nanoscopically presented platelet glycoprotein Ibα

Kruss S, Erpenbeck L, Amschler K, Mundinger TA, Boehm H, Helms HJ, Friede T, Andrews RK, Schön MP, Spatz JP

(2013), ACS Nano, 7(11), 9984-96

The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation

Krishna SM, Dear A, Craig JM, Norman PE, Golledge J

(2013), Atherosclerosis, 228(2), 295-305

The role of leukemia inhibitory factor in tubal ectopic pregnancy

Krishnan T, Winship A, Sonderegger S, Menkhorst E, Horne AW, Brown J, Zhang JG, Nicola NA, Tong S, Dimitriadis E

(2013), Placenta, 34(11), 1014-9

Fanconi anemia proteins interact with CtBP1 and modulate the expression of the Wnt antagonist Dickkopf-1

Huard CC, Tremblay CS, Helsper K, Delisle MC, Schindler D, Lévesque G, Carreau M

(2013), Blood, 121(10), 1729-39

Phase I pilot clinical trial of antenatal maternally administered melatonin to decrease the level of oxidative stress in human pregnancies affected by pre-eclampsia (PAMPR): study protocol

Hobson SR, Lim R, Gardiner EE, Alers NO, Wallace EM

(2013), BMJ Open, 3(9), e003788

Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein

Herold MJ, Rohrbeck L, Lang MJ, Grumont R, Gerondakis S, Tai L, Bouillet P, Kaufmann T, Strasser A

(2013), EMBO Rep, 14(11), 992-8

AKT Isoforms 1 and 3 regulate basal and epidermal growth factor-stimulated SGHPL-5 trophoblast cell migration in humans

Haslinger P, Haider S, Sonderegger S, Otten JV, Pollheimer J, Whitley G, Knöfler M

(2013), Biol Reprod, 88(3), 54

The effect of dabigatran on the activated partial thromboplastin time and thrombin time as determined by the Hemoclot thrombin inhibitor assay in patient plasma samples

Hapgood G, Butler J, Malan E, Chunilal S, Tran H

(2013), Thromb Haemost, 110(2), 308-15

Efficient ROSA26-based conditional and/or inducible transgenesis using RMCE-compatible F1 hybrid mouse embryonic stem cells

Haenebalcke L, Goossens S, Naessens M, Kruse N, Farhang Ghahremani M, Bartunkova S, Haigh K, Pieters T, Dierickx P, Drogat B, Nyabi O, Wirth D, Haigh JJ

(2013), Stem Cell Rev Rep, 9(6), 774-85

Rituximab is associated with improved survival for aggressive B cell CNS lymphoma

Gregory G, Arumugaswamy A, Leung T, Chan KL, Abikhair M, Tam C, Bajel A, Cher L, Grigg A, Ritchie D, Opat S

(2013), Neuro Oncol, 15(8), 1068-73

Akt1 is the principal Akt isoform regulating apoptosis in limiting cytokine concentrations

Green BD, Jabbour AM, Sandow JJ, Riffkin CD, Masouras D, Daunt CP, Salmanidis M, Brumatti G, Hemmings BA, Guthridge MA, Pearson RB, Ekert PG

(2013), Cell Death Differ, 20(10), 1341-9

The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi

Ghasemzadeh M, Kaplan ZS, Alwis I, Schoenwaelder SM, Ashworth KJ, Westein E, Hosseini E, Salem HH, Slattery R, McColl SR, Hickey MJ, Ruggeri ZM, Yuan Y, Jackson SP

(2013), Blood, 121(22), 4555-66

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