Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Days at Home after Surgery: An Integrated and Efficient Outcome Measure for Clinical Trials and Quality Assurance

Bell, Max; Eriksson, Lars I.; Svensson, Tobias; Hallqvist, Linn; Granath, Fredrik; Reilly, Jennifer; Myles, Paul S.

(2019), eClin Med, (11), 18-26.

DOI: 10.1016/j.eclinm.2019.04.011

Global coagulation assays in patients with multiple myeloma and monoclonal gammopathy of unknown significance

Lim, Hui Yin; Brook, Rowena; Krishnamoorthi, Brintha; Tacey, Mark; Leung, Teresa; Donnan, Geoffrey; Nandurkar, Harshal; Ho, Prahlad

(2019), THROMB RES, (183), 45-48.

DOI: 10.1016/j.thromres.2019.10.017

SerpinB2 deficiency in mice reduces bleeding times via dysregulated platelet activation

Schroder, Wayne A.; Le, Thuy T.; Gardner, Joy; Andrews, Robert K.; Gardiner, Elizabeth E.; Callaway, Leonie; Suhrbier, Andreas

(2019), PLATELETS, 30(5), 658-663.

DOI: 10.1080/09537104.2018.1535702

PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia

McRae, Helen M.; Garnham, Alexandra L.; Hu, Yifang; Witkowski, Matthew T.; Corbett, Mark A.; Dixon, Mathew P.; May, Rose E.; Sheikh, Bilal N.; Chiang, William; Kueh, Andrew J.; Nguyen, Tan A.; Man, Kevin; Gloury, Renee; Aubrey, Brandon J.; Policheni, Antonia; Di Rago, Ladina; Alexander, Warren S.; Gray, Daniel H.D.; Strasser, Andreas; Hawkins, Edwin D.; Wilcox, Stephen; Gécz, Jozef; Kallies, Axel; McCormack, Matthew P.; Smyth, Gordon K.; Voss, Anne K.; Thomas, Tim

(2019), BLOOD, 133(16), 1729-1741.

DOI: 10.1182/blood-2018-07-860726

A comparison of global coagulation assays between normal controls and patients with thrombocytopenia

Lim, Hui Yin; Leung, Patrick; Manitta, Vanessa; Nandurkar, Harshal; Ho, Prahlad

(2019), INT J LAB HEMATOL, 41(2), 184-191.

DOI: 10.1111/ijlh.12941

Platelet protein disulfide isomerase promotes glycoprotein ib&-mediated platelet-neutrophil interactions under thromboinflammatory conditions

Li, Jing; Kim, Kyungho; Jeong, Si Yeon; Chiu, Joyce; Xiong, Bei; Petukhov, Pavel A.; Dai, Xiangrong; Li, Xiaoyi; Andrews, Robert K.; Du, Xiaoping; Hogg, Philip J.; Cho, Jaehyung

(2019), CIRCULATION, 139(10), 1300-1319.

DOI: 10.1161/CIRCULATIONAHA.118.036323

Hemopoietic Cell Kinase amplification with Protein Tyrosine Phosphatase Receptor T depletion leads to polycythemia, aberrant marrow erythoid maturation, and splenomegaly

Ku, Matthew; MacKinnon, Ruth N.; Wall, Meaghan; Narayan, Nisha; Walkley, Carl; Cheng, Heung Chin; Campbell, Lynda J.; Purton, Louise E.; Nandurkar, Harshal

(2019), SCI REP-UK, 9(1), 7050

DOI: 10.1038/s41598-019-43373-6

Phase 2 study of all-oral ixazomib, cyclophosphamide and low-dose dexamethasone for relapsed/refractory multiple myeloma

Kumar, Shaji K.; Grzasko, Norbert; Delimpasi, Sosana; Jedrzejczak, Wieslaw W.; Grosicki, Sebastian; Kyrtsonis, Marie Christine; Spencer, Andrew; Gupta, Neeraj; Teng, Zhaoyang; Byrne, Catriona; Labotka, Richard; Dimopoulos, Meletios A.

(2019), BRIT J HAEMATOL, 184(4), 536-546.

DOI: 10.1111/bjh.15679

Tranexamic acid modulates the immune response and reduces postsurgical infection rates

Draxler, Dominik F.; Yep, Kah; Hanafi, Gryselda; Winton, Anoushka; Daglas, Maria; Ho, Heidi; Sashindranath, Maithili; Wutzlhofer, Lisa M.; Forbes, Andrew; Goncalves, Isaac; Tran, Huyen A.; Wallace, Sophia; Plebanski, Magdalena; Myles, Paul S.; Medcalf, Robert L.

(2019), Blood Adv, 3(10), 1598-1609.

DOI: 10.1182/bloodadvances.2019000092

Tranexamic acid modulates the cellular immune profile after traumatic brain injury in mice without hyperfibrinolysis

Draxler, Dominik F.; Daglas, Maria; Fernando, Anushka; Hanafi, Gryselda; McCutcheon, Fiona; Ho, Heidi; Galle, Adam; Gregory, Julia; Larsson, Pia; Keragala, Charithani; Wright, David K.; Tavancheh, Elnaz; Au, Amanda E.; Niego, Be'eri; Wilson, Kirsty; Plebanski, Magdalena; Sashindranath, Maithili; Medcalf, Robert L.

(2019), J THROMB HAEMOST, 17(12), 2174-2187.

DOI: 10.1111/jth.14603

Shared roles for Scl and Lyl1 in murine platelet production and function

Chiu, Sung K.; Orive, Stephanie L.; Moon, Mitchell J.; Saw, Jesslyn; Ellis, Sarah; Kile, Benjamin T.; Huang, Yizhou; Chacon, Diego; Pimanda, John E.; Beck, Dominik; Hamilton, Justin R.; Tremblay, Cedric S.; Curtis, David J.

(2019), BLOOD, 134(10), 826-835.

DOI: 10.1182/blood.2019896175

Clinical coding data algorithm to categorize type of gastrointestinal bleeding as a primary reason for massive transfusion

Ket, Shara N.; Sparrow, Rosemary L.; McQuilten, Zoe K.; Tacey, Mark; Gibson, Peter R.; Brown, Gregor J.; Wood, Erica M.

(2019), VOX SANG, 114(8), 853-860.

DOI: 10.1111/vox.12840

Antiphospholipid syndrome: a clinical review

Mezhov, Veronica; Segan, Julian D.; Tran, Huyen; Cicuttini, Flavia M.

(2019), MED J AUSTRALIA, 211(4), 184-188.

DOI: 10.5694/mja2.50262

T-PA suppresses the immune response and aggravates neurological deficit in a murine model of ischemic stroke

Draxler, Dominik F.; Lee, Felix; Ho, Heidi; Keragala, Charithani B.; Medcalf, Robert L.; Niego, Be'eri

(2019), FRONT IMMUNOL, 10, MAR

DOI: 10.3389/fimmu.2019.00591

Intestinal gases: Influence on Gut Disorders and the Role of Dietary Manipulations

Kalantar-Zadeh, Kourosh; Berean, Kyle J.; Burgell, Rebecca E.; Muir, Jane G.; Gibson, Peter R.

(2019), NAT REV GASTRO HEPAT, 16(12), 733-747.

DOI: 10.1038/s41575-019-0193-z

Shear-Dependent Platelet Aggregation

Rana, Akshita; Westein, Erik; Niego, Be'eri; Hagemeyer, Christoph E.

(2019), Front Cardiovasc Med, 6, 141

DOI: 10.3389/fcvm.2019.00141

Gluten-free and low-FODMAP sourdoughs for patients with coeliac disease and irritable bowel syndrome

Muir, J. G.; Varney, J. E.; Ajamian, M.; Gibson, P. R.

(2019), INT J FOOD MICROBIOL, (290), 237-246.

DOI: 10.1016/j.ijfoodmicro.2018.10.016

Oxacillin Coupled G-Quadruplexes as a Novel Biofilm-Specific Antibiotic for Staphylococcus aureus Biofilms

Fenati, Renzo A.; Locock, Katherine; Qu, Yue; Ellis, Amanda V.

(2019), ACS Appl Bio Mater, 2(7), 3002-3008.

DOI: 10.1021/acsabm.9b00336

Novel stenotic microchannels to study thrombus formation in shear gradients

Lui, Mathew; Gardiner, Elizabeth E.; Arthur, Jane F.; Pinar, Isaac; Lee, Woei Ming; Ryan, Kris; Carberry, Josie; Andrews, Robert K.

(2019), INT J MOL SCI, 20(12), 2967

DOI: 10.3390/ijms20122967

How much space do drivers provide when passing cyclists? Understanding the impact of motor vehicle and infrastructure characteristics on passing distance

Beck, Ben; Chong, Derek; Olivier, Jake; Perkins, Monica; Tsay, Anthony; Rushford, Adam; Li, Lingxiao; Cameron, Peter; Fry, Richard; Johnson, Marilyn

(2019), ACCIDENT ANAL PREV, (128), 253-260.

DOI: 10.1016/j.aap.2019.03.007