Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Comparison of placebo and best available therapy for the treatment of myelofibrosis in the phase 3 COMFORT studies

Mesa RA, Kiladjian JJ, Verstovsek S, Al-Ali HK, Gotlib J, Gisslinger H, Levy R, Siulnik A, Gupta V, Khan M, DiPersio JF, McQuitty M, Catalano JV, Hunter DS, Knoops L, Deininger M, Cervantes F, Miller C, Vannucchi AM, Silver RT, Barbui T, Talpaz M, Barosi

(2014), Haematologica, 99(2), 292-8

Changing microbial epidemiology in hematopoietic stem cell transplant recipients: increasing resistance over a 9-year period

Macesic N, Morrissey CO, Cheng AC, Spencer A, Peleg AY

(2014), Transpl Infect Dis, 16(6), 887-96

A multicentre retrospective comparison of central nervous system prophylaxis strategies among patients with high-risk diffuse large B-cell lymphoma

Cheah CY, Herbert KE, O'Rourke K, Kennedy GA, George A, Fedele PL, Gilbertson M, Tan SY, Ritchie DS, Opat SS, Prince HM, Dickinson M, Burbury K, Wolf M, Januszewicz EH, Tam CS, Westerman DA, Carney DA, Harrison SJ, Seymour JF

(2014), Br J Cancer, 111(6), 1072-9

Lenalidomide and dexamethasone in transplant-ineligible patients with myeloma

Benboubker L, Dimopoulos MA, Dispenzieri A, Catalano J, Belch AR, Cavo M, Pinto A, Weisel K, Ludwig H, Bahlis N, Banos A, Tiab M, Delforge M, Cavenagh J, Geraldes C, Lee JJ, Chen C, Oriol A, de la Rubia J, Qiu L, White DJ, Binder D, Anderson K, Fermand JP

(2014), N Engl J Med, 371(10), 906-17

Consensus guidelines for the use of empiric and diagnostic-driven antifungal treatment strategies in haematological malignancy, 2014

Morrissey CO, Gilroy NM, Macesic N, Walker P, Ananda-Rajah M, May M, Heath CH, Grigg A, Bardy PG, Kwan J, Kirsa SW, Slavin M, Gottlieb T, Chen S

(2014), Intern Med J, 44(12b), 1298-314

The dual-specificity phosphatase 2 (DUSP2) does not regulate obesity-associated inflammation or insulin resistance in mice

Lancaster GI, Kraakman MJ, Kammoun HL, Langley KG, Estevez E, Banerjee A, Grumont RJ, Febbraio MA, Gerondakis S

(2014), PLoS One, 9(11), e111524

Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia

Hawkins ED, Oliaro J, Ramsbottom KM, Ting SB, Sacirbegovic F, Harvey M, Kinwell T, Ghysdael J, Johnstone RW, Humbert PO, Russell SM

(2014), PLoS One, 9(1), e87376

c-Rel regulates Ezh2 expression in activated lymphocytes and malignant lymphoid cells

Neo WH, Lim JF, Grumont R, Gerondakis S, Su IH

(2014), J Biol Chem, 289(46), 31693-707

Author reply

Wei A, Fleming S

(2014), Intern Med J, 44(8), 825

Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets

Wang X, Palasubramaniam J, Gkanatsas Y, Hohmann JD, Westein E, Kanojia R, Alt K, Huang D, Jia F, Ahrens I, Medcalf RL, Peter K, Hagemeyer CE

(2014), Circ Res, 114(7), 1083-93

The clonal evolution of leukemic stem cells in T-cell acute lymphoblastic leukemia

Tremblay CS, Curtis DJ

(2014), Curr Opin Hematol, 21(4), 320-5

New oral anticoagulants: a practical guide on prescription, laboratory testing and peri-procedural/bleeding management. Australasian Society of Thrombosis and Haemostasis

Tran H, Joseph J, Young L, McRae S, Curnow J, Nandurkar H, Wood P, McLintock C

(2014), Intern Med J, 44(6), 525-36

Species-Specific Regulation of t-PA and PAI-1 Gene Expression in Human and Rat Astrocytes

Tjärnlund-Wolf A, Hultman K, Blomstrand F, Nilsson M, Medcalf RL, Jern C

(2014), Gene Regul Syst Bio, 8, 113-8

ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins

Tatari MN, De Craene B, Soen B, Taminau J, Vermassen P, Goossens S, Haigh K, Cazzola S, Lambert J, Huylebroeck D, Haigh JJ, Berx G

(2014), Cell Mol Life Sci, 71(18), 3599-609

The novel AKT inhibitor afuresertib shows favorable safety, pharmacokinetics, and clinical activity in multiple myeloma

Spencer A, Yoon SS, Harrison SJ, Morris SR, Smith DA, Brigandi RA, Gauvin J, Kumar R, Opalinska JB, Chen C

(2014), Blood, 124(14), 2190-5

Differential signaling by protease-activated receptors: implications for therapeutic targeting

Sidhu TS, French SL, Hamilton JR

(2014), Int J Mol Sci, 15(4), 6169-83

N-Acetylcysteine for thrombotic thrombocytopenic purpura: is a von Willebrand factor-inhibitory dose feasible in vivo?

Shortt J, Opat SS, Wood EM

(2014), Transfusion, 54(9), 2362-3

Phase 2 randomized study of bortezomib-melphalan-prednisone with or without siltuximab (anti-IL-6) in multiple myeloma

San-Miguel J, Bladé J, Shpilberg O, Grosicki S, Maloisel F, Min CK, Polo Zarzuela M, Robak T, Prasad SV, Tee Goh Y, Laubach J, Spencer A, Mateos MV, Palumbo A, Puchalski T, Reddy M, Uhlar C, Qin X, van de Velde H, Xie H, Orlowski RZ

(2014), Blood, 123(26), 4136-42

Oxidation of an exposed methionine instigates the aggregation of glyceraldehyde-3-phosphate dehydrogenase

Samson AL, Knaupp AS, Kass I, Kleifeld O, Marijanovic EM, Hughes VA, Lupton CJ, Buckle AM, Bottomley SP, Medcalf RL

(2014), J Biol Chem, 289(39), 26922-36

A novel agent with histone deacetylase inhibitory activity attenuates neointimal hyperplasia

Rahmatzadeh M, Liu HB, Krishna SM, Gaspari TA, Welungoda I, Widdop RE, Dear AE

(2014), Cardiovasc Drugs Ther, 28(5), 395-406

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