Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Venetoclax combined with low-dose cytarabine for previously untreated patients with acute myeloid leukemia

Wei, Andrew H.; Strickland, Stephen A.; Hou, Jing Zhou; Fiedler, Walter; Lin, Tara L.; Walter, Roland B.; Enjeti, Anoop; Tiong, Ing Soo; Savona, Michael; Lee, Sangmin; Chyla, Brenda; Popovic, Relja; Salem, Ahmed Hamed; Agarwal, Suresh; Xu, Tu; Fakouhi, Kaffa M.; Humerickhouse, Rod; Hong, Wan Jen; Hayslip, John; Roboz, Gail J.

(2019), J CLIN ONCOL, 37(15), 1277-1284.

DOI: 10.1200/JCO.18.01600

Polyclonal heterogeneity: The New Norm for Secondary Clinical Resistance to Targeted Monotherapy in Relapsed Leukemia?

Wei, Andrew H.; Roberts, Andrew W.

(2019), CANCER DISCOV, 9(8), 998-1000.

DOI: 10.1158/2159-8290.CD-19-0575

Chromosomal Abnormalities and Prognosis in NPM1-Mutated Acute Myeloid Leukemia: A Pooled Analysis of Individual Patient Data From Nine International Cohorts.

Wei, Andrew; Angenendt, Linus; Röllig, Christoph; Montesinos, Pau; Martínez-Cuadrón, David; Barragán, Eva; García, Raimundo; Botella, Carmen; Martínez, Pilar; Ravandi, Farhad; Kadia, Tapan; Kantarjian, Hagop M.; Cortes, Jorge; Juliusson, Gunnar; Lazarevic, Vladimir; Höglund, Martin; Lehmann, Sören; Recher, Christian; Pigneux, Arnaud; Bertoli, Sarah; Dumas, Pierre-Yves; Dombret, Hervé; Preudhomme, Claude; Micol, Jean-Baptiste; Terré, Christine; Ráčil, Zdeněk; Novak, Jan; Zak, Pavel; Tiong, Ing Soo; Wall, Meaghan; Estey, Elihu; Shaw, Carole; Exeler, Rita; Wagenführ, Lisa

(2019), J CLIN ONCOL, 37(29), 2632-2642.

DOI: 10.1200/JCO.19.00416

BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals

Srivastava, Rahul; Cao, Zhipeng; Nedeva, Christina; Naim, Samara; Bachmann, Daniel; Rabachini, Tatiana; Gangoda, Lahiru; Shahi, Sanjay; Glab, Jason; Menassa, Joseph; Osellame, Laura; Nelson, Tao; Fernandez-Marrero, Yuniel; Brown, Fiona; Wei, Andrew; Ke, Francine; O'Reilly, Lorraine; Doerflinger, Marcel; Allison, Cody; Kueh, Andrew; Ramsay, Rob; Smith, Brian J.; Mathivanan, Suresh; Kaufmann, Thomas; Puthalakath, Hamsa

(2019), P NATL ACAD SCI USA, 116(31), 15469-15474.

DOI: 10.1073/pnas.1904523116

Incorporating precision BH3 warheads into the offensive against acute myeloid leukemia

Savona, Michael R.; Wei, Andrew H.

(2019), J CLIN ONCOL, 37(21), 1785-1789.

DOI: 10.1200/JCO.19.00400

ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms

Goossens, Steven; Wang, Jueqiong; Tremblay, Cedric S.; De Medts, Jelle; T'sas, Sara; Nguyen, Thao; Saw, Jesslyn; Haigh, Katharina; Curtis, David J.; Van Vlierberghe, Pieter; Berx, Geert; Taghon, Tom; Haigh, Jody J.

(2019), HAEMATOLOGICA, 104(8), 1608-1616.

DOI: 10.3324/haematol.2018.207837

Blinatumomab versus chemotherapy in first salvage or in later salvage for B-cell precursor acute lymphoblastic leukemia

Dombret, Hervé; Topp, Max S.; Schuh, Andre C.; Wei, Andrew H.; Durrant, Simon; Bacon, Christopher Larry; Tran, Qui; Zimmerman, Zachary; Kantarjian, Hagop

(2019), LEUKEMIA LYMPHOMA, 60(9), 2214-2222

DOI: 10.1080/10428194.2019.1576872

Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia

DiNardo, Courtney D.; Pratz, Keith; Pullarkat, Vinod; Jonas, Brian A.; Arellano, Martha; Becker, Pamela S.; Frankfurt, Olga; Konopleva, Marina; Wei, Andrew H.; Kantarjian, Hagop M.; Xu, Tu; Hong, Wan Jen; Chyla, Brenda; Potluri, Jalaja; Pollyea, Daniel A.; Letai, Anthony

(2019), BLOOD, 133(1), 7-17.

DOI: 10.1182/blood-2018-08-868752

Adenosine and Forskolin Inhibit Platelet Aggregation by Collagen but not the Proximal Signalling Events

Clark, Joanne C.; Kavanagh, Deirdre M.; Watson, Stephanie; Pike, Jeremy A.; Andrews, Robert K.; Gardiner, Elizabeth E.; Poulter, Natalie S.; Hill, Stephen J.; Watson, Steve P.

(2019), THROMB HAEMOSTASIS, 119(7), 1124-1137.

DOI: 10.1055/s-0039-1688788

Utility of circulating cell-free RNA analysis for the characterization of global transcriptome profiles of multiple myeloma patients

Chen, Maoshan; Mithraprabhu, Sridurga; Ramachandran, Malarmathy; Choi, Kawa; Khong, Tiffany; Spencer, Andrew

(2019), CANCERS, 11(6), 887

DOI: 10.3390/cancers11060887

Sez6 levels are elevated in cerebrospinal fluid of patients with inflammatory pain-associated conditions

Roitman, Maria; Edgington-Mitchell, Laura E.; Mangum, Jon; Ziogas, James; Adamides, Alexios A.; Myles, Paul; Choo-Bunnett, Hearan; Bunnett, Nigel W.; Gunnersen, Jenny M.

(2019), Pain Reports, 4(2), e719.

DOI: 10.1097/PR9.0000000000000719

IV Fluids for Major Surgery

Myles, Paul S.; Miller, Timothy E.

(2019), ANESTHESIOLOGY, 131(6), 1368-1369.

DOI: 10.1097/ALN.0000000000003003

Anaesthetic depth and complications after major surgery: an international, randomised controlled trial

Short, Timothy G.; Campbell, Douglas; Frampton, Christopher; Chan, Matthew T.V.; Myles, Paul S.; Corcoran, Tomás B.; Sessler, Daniel I.; Mills, Gary H.; Cata, Juan P.; Painter, Thomas; Byrne, Kelly; Han, Ruquan; Chu, Mandy H.M.; McAllister, Davina J.; Leslie, Kate; Shulman, M.; Wallace, S.; Farrington, C.; Gallagher, W.; Ditoro, A.; Peyton, P.; Baulch, S.; Dalyell, A.; Sidiropoulos, S.; Rowley, J.; Tan, N.; McCallum, D.; O'Loughlin, E.; Wong, S.; Owen, K.; Sim, I. K.; Glazov, L.; Coutts, P.; Pushpanathan, M.; Findlay, V.; Paech, M.; Cavill, D.; Chuan, A.; Pope, L.; Lucas, J.; Robinson, B.; Millard, A.; Allen, S.; Allen, M.; McKeown, S.; Sivalingam, P.; Wilkes, T.; Jowett, C.; Kearney, A.; Bennett, M.; Favero, J. P.; Sawhney, S.; Drummond, K.; Osborn, S.; Wing, A.; Taylor, J.; Edwards, M.; Reynolds, H.; Town, C.; Terblanche, N.; Challis, M.; Seale, R.; Button, K.; Cotter, R.; Stewart, M.; Zingerle, N.; Hannon, S.; Middleton, D.; Edgley, C.; March, S.; McCulloch, T.; Wong, G.; Jeong, S.; Connell, K.; Kramer, K.; Henderson, G.; Ward, V.; Buller, Y.; Hird, N.; Scott, D.; Evered, L.; Snyder, G.; Silbert, B.; Corcoran, P.; Fitzgerald, E.; Said, S.; Watson, A.; Baby, D.; Bolsin, S.; Marriott, A.; Ives, K.; Wakefeld, B. J.; Jeffreys, A.; Bates, S.; Halliwell, R.; Elliott, D.; Cope, L.; Paranthoiene, R.; Peng, P.; Liu, X.; Zhou, X.; Jin, X.; Liu, H.; An, L.; Cui, W.; Zhang, L.; Jia, B.; Fang, J.; Koo, E.; Lo, E.; Fung, B.; Tsang, M.; Lam, L.; Pang, E.; Lau, V.; Choi, G.; Kwok, R.; Yau, K.; Cheng, B.; Lam, C.; Lee, E.; Buggy, D.; Keane, H.; Byrne, K.; Connolly, C.; Ali, M.; Cervantes, A.; Kumar, K.; Dandy, S.; Ritchie, L.; Kennedy, R.; McKellow, M.; Read, C.; France, D.; Truong, H.; Chapman, C.; Walker, S.; Olliff, S.; Houston, H.; Scott, M.; Minchin, I.; Moniwa, A.; McAlpine, J.; Chaddock, M.; Gray, L.; Czepanski, C.; Vinish, S.; Buehner, U.; Williams, E.; Zhou, C.; Goodman, L.; Bermaat, J.; Mans, G.; Garden, A.; Franks, R.; Deiterle, J.; Barrett, J.; Roubos, S.; van Lier, F.; Verbrugge, S.; Kalkman, C.; Dieleman, J.; Verdam-Veldkamp, J.; van Kampen, A.; Pai, A.; Sevillano, A.; Yeung, J.; Melody, T.; Atterbury, K.; Hough, M.; Dukes, S.; Williams, S.; Milan, Z.; Kunst, G.; Bhatia, K.; MacNab, W.; Weaver, E.; Moulding, R.; Doble, P.; Klepsch, P.; Self, J.; Howes, T.; Rees, B.; Faulkner, B.; Blackburn, J.; Crombie, N.; Cooper, L.; Nair, A.; Bell, G.; Longfellow, R.; Nicholas, C.; Garratt, T.; Pollard, M.; Brown, G.; Morrison, G.; Lang, A.; Dawson, H.; MacDonald, M.; Martin, T.; Niebrzegowska, E.; Dias, P.; Rao Baikady, R.; Jhanji, S.; Siddaiah, N.; Bird, L.; Mittal, R.; Nalawaya, P.; Sonksen, J.; Gidda, R.; Wrench, I.; Craw, N.; Pippard, L.; Davies, S.; Wright, M.; Turan, M.; Maheshwari, K.; Cohen, B.; Saasouh, W.; Singh, P.; Govindarajan, S.; Cuko, E.; Marcano, F.; Babazade, R.; Leung, S.; Raza, S.; Reville, E.; Hanline, C.; Ayad, S.; Buttar, M.; Akhtar, Z.; Niazi, A.; Saha, P.; Morris, A.; Lokhande, C.; Hassan, M.; Honar, H.; Bairacharya, G.; Saxon, J.; Chelnick, D.; Carlson, R.; Ruiz, J.; Wilks, J.; Williams, W.; Dangler, L.; Ifeanyi-Pillette, I.; Suarez, J.; Erfe, R.; Perez, A.; Veselis, R.; Yang, G.; , ; ,

(2019), LANCET, 394(10212), 1907-1914.

DOI: 10.1016/S0140-6736(19)32315-3

Characterization of inhibitory failure in Multiple Sclerosis

Ternes, Anne Marie; Clough, Meaghan; Foletta, Paige; White, Owen; Fielding, Joanne

(2019), J CLIN EXP NEUROPSYC, 41(3), 320-329

DOI: 10.1080/13803395.2018.1552756

High-Frequency Neuronal Oscillatory Abnormalities in the Phospholipase C-β1 Knockout Mouse Model of Schizophrenia

Hudson, Matthew R.; Hannan, Anthony J.; O'Brien, Terence J.; Jones, Nigel C.

(2019), INT J NEUROPSYCHOPH, 22(3), 221-231

DOI: 10.1093/ijnp/pyy097

Dissecting the syndrome of schizophrenia: Associations between symptomatology and hormone levels in women with schizophrenia

Thomas, Natalie; Gurvich, Caroline; Hudaib, Abdul Rahman; Gavrilidis, Emorfia; Kulkarni, Jayashri

(2019), PSYCHIAT RES, 280, 112510

DOI: 10.1016/j.psychres.2019.112510

Functional correlates of cognitive dysfunction in clinically isolated syndromes

Gajamange, Sanuji; Shelton, Annie; Clough, Meaghan; White, Owen; Fielding, Joanne; Kolbe, Scott

(2019), PLOS ONE, 14(7), e0219590

DOI: 10.1371/journal.pone.0219590

Clinical utility and prospective of TMS–EEG

Tremblay, Sara; Rogasch, Nigel C.; Premoli, Isabella; Blumberger, Daniel M.; Casarotto, Silvia; Chen, Robert; Di Lazzaro, Vincenzo; Farzan, Faranak; Ferrarelli, Fabio; Fitzgerald, Paul B.; Hui, Jeanette; Ilmoniemi, Risto J.; Kimiskidis, Vasilios K.; Kugiumtzis, Dimitris; Lioumis, Pantelis; Pascual-Leone, Alvaro; Pellicciari, Maria Concetta; Rajji, Tarek; Thut, Gregor; Zomorrodi, Reza; Ziemann, Ulf; Daskalakis, Zafiris J.

(2019), CLIN NEUROPHYSIOL, 130(5), 802-844.

DOI: 10.1016/j.clinph.2019.01.001

Disordered eating behaviours and eating disorders in women in australia with and without polycystic ovary syndrome

Pirotta, Stephanie; Barillaro, Mary; Brennan, Leah; Grassi, Angela; Jeanes, Yvonne M.; Joham, Anju E.; Kulkarni, Jayashri; Monahan Couch, Lynn; Lim, Siew; Moran, Lisa

(2019), J CLIN MED, 8(10), 1682

DOI: 10.3390/jcm8101682

Do schizotypy dimensions reflect the symptoms of schizophrenia?

Thomas, Elizabeth H.X.; Rossell, Susan L.; Tan, Eric J.; Neill, Erica; Van Rheenen, Tamsyn E.; Carruthers, Sean P.; Sumner, Philip J.; Louise, Stephanie; Bozaoglu, Kiymet; Gurvich, Caroline

(2019), AUST NZ J PSYCHIAT, 53(3), 236-247.

DOI: 10.1177/0004867418769746

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