Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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The effects of ALV003 pre-digestion of gluten on immune response and symptoms in celiac disease in vivo

Tye-Din JA, Anderson RP, Ffrench RA, Brown GJ, Hodsman P, Siegel M, Botwick W, Shreeniwas R

(2010), Clin Immunol, 134(3), 289-95

The appropriateness of concomitant immunomodulators with anti-tumor necrosis factor agents for Crohn's disease: one size does not fit all

Melmed GY, Spiegel BM, Bressler B, Cheifetz AS, Devlin SM, Harrell LE, Irving PM, Jones J, Kaplan GG, Kozuch PL, Velayos FS, Baidoo L, Sparrow MP, Siegel CA

(2010), Clin Gastroenterol Hepatol, 8(8), 655-9

IBD: Switching metabolism-can two drugs be better than one?

Sparrow M

(2010), Nat Rev Gastroenterol Hepatol, 7(8), 420-2

Practical guidelines for treating inflammatory bowel disease safely with anti-tumour necrosis factor therapy in Australia

Connell W, Andrews JM, Brown S, Sparrow M

(2010), Intern Med J, 40(2), 139-49

Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomised, double-blind, placebo-controlled, dose-escalation trial

Gane EJ, Roberts SK, Stedman CA, Angus PW, Ritchie B, Elston R, Ipe D, Morcos PN, Baher L, Najera I, Chu T, Lopatin U, Berrey MM, Bradford W, Laughlin M, Shulman NS, Smith PF

(2010), Lancet, 376(9751), 1467-75

A Phase I clinical trial of dendritic cell immunotherapy in HCV-infected individuals

Gowans EJ, Roberts S, Jones K, Dinatale I, Latour PA, Chua B, Eriksson EM, Chin R, Li S, Wall DM, Sparrow RL, Moloney J, Loudovaris M, Ffrench R, Prince HM, Hart D, Zeng W, Torresi J, Brown LE, Jackson DC

(2010), J Hepatol, 53(4), 599-607

Low virological response and high relapse rates in hepatitis C genotype 1 patients with advanced fibrosis despite adequate therapeutic dosing

Cheng WS, Roberts SK, McCaughan G, Sievert W, Weltman M, Crawford D, Rawlinson W, Marks PS, Thommes J, Rizkalla B, Yoshihara M, Dore GJ; CHARIOT Study Group

(2010), J Hepatol, 53(4), 616-23

Azathioprine and allopurinol: a two-edged interaction

Gearry RB, Day AS, Barclay ML, Leong RW, Sparrow MP

(2010), J Gastroenterol Hepatol, 25(4), 653-5

Viral response guided therapy for hepatitis C in the approaching era of direct acting anti-viral agents

Berzsenyi MD, Roberts SK

(2010), J Gastroenterol Hepatol, 25(4), 655-6

Efficacy and safety of peginterferon alfa-2a (40KD) plus ribavirin in hepatitis C patients with advanced fibrosis and cirrhosis

Bruno S, Shiffman ML, Roberts SK, Gane EJ, Messinger D, Hadziyannis SJ, Marcellin P

(2010), Hepatology, 51(2), 388-97

Chronic urotensin-II infusion induces diastolic dysfunction and enhances collagen production in rats

Tran L, Kompa AR, Kemp W, Phrommintikul A, Wang BH, Krum H

(2010), Am J Physiol Heart Circ Physiol, 298(2), H608-13

How do you monitor patients on azathioprine/6-mercaptopurine?

Sparrow MP

(2009), In: Rubin DT, Friedman S, Farraye FA (eds) Curbside Consultations in IBD: 49 Clinical Questions, SLACK Incorporated, USA, Chapter 9, 39-44

Characterization of inflammatory bowel disease with urinary metabolic profiling

Williams HR, Cox IJ, Walker DG, North BV, Patel VM, Marshall SE, Jewell DP, Ghosh S, Thomas HJ, Teare JP, Jakobovits S, Zeki S, Welsh KI, Taylor-Robinson SD,Orchard TR

(2009), Am J Gastroenterol, 104(6), 1435-44

Optimizing conventional therapies for inflammatory bowel disease

Sparrow MP, Irving PM, Hanauer SB

(2009), Curr Gastroenterol Rep, 11(6), 496-503

Impact of high-dose peginterferon alfa-2A on virological response rates in patients with hepatitis C genotype 1: a randomized controlled trial

Roberts SK, Weltman MD, Crawford DH, McCaughan GW, Sievert W, Cheng WS, Rawlinson W, Desmond PV, Marks PS, Yoshihara M, Rizkalla B, Depamphilis JK, Dore GJ; Chariot Study Group

(2009), Hepatology, 50(4), 1045-55

Feasibility of video capsule endoscopy in the management of children with peutz-jeghers syndrome: a blinded comparison with barium enterography for the detection of small bowel polyps

Postgate A, Hyer W, Phillips R, Gupta A, Burling D, Bartram C, Marshall M, Taylor S, Brown G, Schofield G, Bassett P, Spray C, Fitzpatrick A, Fraser C, Latchford A

(2009), J Pediatr Gastroenterol Nutr, 49(4), 417-23

Analysis of FOXP3+ regulatory T cells that display apparent viral antigen specificity during chronic hepatitis C virus infection

Li S, Floess S, Hamann A, Gaudieri S, Lucas A, Hellard M, Roberts S, Paukovic G, Plebanski M, Loveland BE, Aitken C, Barry S, Schofield L, Gowans EJ

(2009), PLoS Pathog, 5(12), e1000707

Long term efficacy and safety of allopurinol and azathioprine or 6-mercaptopurine in patients with inflammatory bowel disease

Leung Y, Sparrow MP, Schwartz, M and Hanauer SB

(2009), J Crohns Colitis, 3(3), 162-67

Thiopurines, a previously unrecognized cause for fatigue in patients with inflammatory bowel disease

Lee TW, Iser J, Sparrow MP, Newnham ED, Headon BJ, Gibson PR

(2009), J Crohns Colitis, 3(3), 196-99

Minimally invasive prediction of esophageal varices and portal hypertension

Kemp W, Roberts S

(2009), J Gastroenterol Hepatol, 24(9), 1480-1

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