Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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The central role of Abeta amyloid in the pathogenesis of Alzheimer's disease

Ritchie C, McLean C, Beyreuther K, Masters CL

(2010), In: Burns A, Ames D, O'Brien P (eds), Dementia, 4th edition, Hodder Arnold, London, UK, Chapter 51, 438-50

In situ detection of inflammatory mediators in post mortem human brain tissue after traumatic injury

Frugier T, Morganti-Kossmann MC, O'Reilly D

(2010), J Neurotrauma, 27(3), 497-507

Cardiac reanimation for donor heart transplantation after cardiocirculatory death

Repse S, Pepe S, Anderson J, McLean C, Rosenfeldt FL

(2010), J Heart Lung Transplant, 29(7), 747-55

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, van Swieten JC...

(2010), Nat Genet, 42(3), 234-9

Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

Blows FM, Driver KE, Schmidt MK, Broeks A, van Leeuwen FE, Wesseling J, Cheang MC, Gelmon K, Nielsen TO, Blomqvist C, Heikkilä P, Heikkinen T, Nevanlinna H, Akslen LA, Bégin LR, Foulkes WD, Couch FJ, Wang X, Cafourek V, Olson JE, Baglietto L, Giles GG...

(2010), PLoS Med, 7(5), e1000279

Evidence for a dominant negative disease mechanism in cap myopathy due to TPM3

Waddell LB, Kreissl M, Kornberg A, Kennedy P, McLean C, Labarre-Vila A, Monnier N, North KN, Clarke NF

(2010), Neuromuscul Disord, 20(7), 464-6

BCL2 in breast cancer: a favourable prognostic marker across molecular subtypes and independent of adjuvant therapy received

Dawson SJ, Makretsov N, Blows FM, Driver KE, Provenzano E, Le Quesne J, Baglietto L, Severi G, Giles GG, McLean CA, Callagy G, Green AR, Ellis I, Gelmon K, Turashvili G, Leung S, Aparicio S, Huntsman D, Caldas C, Pharoah P

(2010), Br J Cancer, 103(5), 668-75

Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease

Duce JA, Tsatsanis A, Cater MA, James SA, Robb E, Wikhe K, Leong SL, Perez K, Johanssen T, Greenough MA, Cho HH, Galatis D, Moir RD, Masters CL, McLean C, Tanzi RE, Cappai R, Barnham KJ, Ciccotosto GD, Rogers JT, Bush AI

(2010), Cell, 142(6), 857-67

Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers

Fedele CG, Ooms LM, Ho M, Vieusseux J, O'Toole SA, Millar EK, Lopez-Knowles E, Sriratana A, Gurung R, Baglietto L, Giles GG, Bailey CG, Rasko JE, Shields BJ, Price JT, Majerus PW, Sutherland RL, Tiganis T, McLean CA, Mitchell CA

(2010), Proc Natl Acad Sci USA, 107(51), 22231-6

Lung transplant survival despite unexpected pulmonary metastatic thyroid cancer in the explant

Paraskeva M, McLean C, Snell GI, Westall GP

(2010), Transpl Int, 23(9), e45-8

11C-PiB PET studies in typical sporadic Creutzfeldt-Jakob disease

Villemagne VL, McLean CA, Reardon K, Boyd A, Lewis V, Klug G, Jones G, Baxendale D, Masters CL, Rowe CC, Collins SJ

(2009), J Neurol Neurosurg Psychiatry, 80(9), 998-1001

Abnormal hippocampal distribution of TDP-43 in patients with-late onset psychosis

Velakoulis D, Walterfang M, Mocellin R, Pantelis C, Dean B, McLean C

(2009), Aust N Z J Psychiatry, 43(8), 739-45

Frontotemporal dementia presenting as schizophrenia-like psychosis in young people: clinicopathological series and review of cases

Velakoulis D, Walterfang M, Mocellin R, Pantelis C, McLean C

(2009), Br J Psychiatry, 194(4), 298-305

Cell-specific temporal infection of the brain in a simian immunodeficiency virus model of human immunodeficiency virus encephalitis

Thompson KA, Varrone JJ, Jankovic-Karasoulos T, Wesselingh SL, McLean CA

(2009), J Neurovirol , 15(4), 300-11

Disease status at autologous stem cell transplantation and the cell of origin phenotype are important predictors of outcome in patients with neurologic (central nervous system) relapse of diffuse large B-cell lymphoma undergoing autologous stem cell......

Patil S, Spencer A, Schwarer A, Avery S, Ritchie D, Opat S, Wei A, McLean C

(2009), Leuk Lymphoma, 50(12), 1964-8

pH measurement as quality control on human post mortem brain tissue: a study of the BrainNet Europe consortium

Monoranu CM, Apfelbacher M, Grünblatt E, Puppe B, Alafuzoff I, Ferrer I, Al-Saraj S, Keyvani K, Schmitt A, Falkai P, Schittenhelm J, Halliday G, Kril J, Harper C, McLean C, Riederer P, Roggendorf W

(2009), Neuropathol Appl Neurobiol, 35(3), 329-37

Tryptophan is a marker of human postmortem brain tissue quality

Grünblatt E, Monoranu CM, Apfelbacher M, Keller D, Michel TM, Alafuzoff I, Ferrer I, Al-Saraj S, Keyvani K, Schmitt A, Falkai P, Schittenhelm J, McLean C, Halliday GM, Harper C, Deckert J, Roggendorf W, Riederer P

(2009), J Neurochem, 110(5), 1400-8

Viliuisk encephalomyelitis in Eastern Siberia – analysis of 390 cases

Goldfarb LG, Vladimirtsev VA, Platanov FA, Lee HS, McLean CA, Masters CL

(2009), Folia Neuropathol, 47(2), 171-81

Characterization of PiB binding to white matter in Alzheimer disease and other dementias

Fodero-Tavoletti MT, Rowe CC, McLean CA, Leone L, Li QX, Masters CL, Cappai R, Villemagne VL

(2009), J Nucl Med, 50(2), 198-204

Juvenile polymyositis or paediatric muscular dystrophy: a detailed re-analysis of 13 cases

D'Arcy CE, Ryan MM, McLean CA

(2009), Histopathology, 55(4), 452-62