Research publications | Alfred Health

Interrupting antiretroviral therapy in HIV cure trials during COVID-19

Lau, Jillian SY; Rasmussen, Thomas A.; Lewin, Sharon R.; Ehm, Adam; Martinez, Cipriano; Burnett, Craig; McMahon, James H.

(2021), J VIRUS ERAD, 7(1), 100032

DOI: 10.1016/j.jve.2021.100032

The impact of immune checkpoint therapy on the latent reservoir in HIV-infected individuals with cancer on antiretroviral therapy

Lau, Jillian S.Y.; McMahon, James H.; Gubser, Celine; Solomon, Ajantha; Chiu, Chris Y.H.; Dantanarayana, Ashanti; Chea, Socheata; Tennakoon, Surekha; Zerbato, Jennifer M.; Garlick, Jill; Morcilla, Vincent; Palmer, Sarah; Lewin, Sharon R.; Rasmussen, Thoma

(2021), AIDS, 35(10), 1631-1636

DOI: 10.1097/QAD.0000000000002919

A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

Lam, Margaret M.C.; Wick, Ryan R.; Watts, Stephen C.; Cerdeira, Louise T.; Wyres, Kelly L.; Holt, Kathryn E.

(2021), NAT COMMUN, 12(1), 4188

DOI: 10.1038/s41467-021-24448-3

The RNA-Binding Proteins SRP14 and HMGB3 Control HIV-1 Tat mRNA Processing and Translation During HIV-1 Latency

Khoury, Georges; Lee, Michelle Y.; Ramarathinam, Sri H.; McMahon, James; Purcell, Anthony W.; Sonza, Secondo; Lewin, Sharon R.; Purcell, Damian F.J.

(2021), FRONT GENET, 12, 680725

DOI: 10.3389/fgene.2021.680725

Multiple introductions of multidrug-resistant typhoid associated with acute infection and asymptomatic carriage, Kenya

Kariuki, Samuel; Dyson, Zoe A.; Mbae, Cecilia; Ngetich, Ronald; Kavai, Susan M.; Wairimu, Celestine; Anyona, Stephen; Gitau, Naomi; Onsare, Robert; Ongadi, Beatrice; Duchene, Sebastian; Ali, Mohamed; Clemens, John; Holt, Kathryn E.; Dougan, Gordon

(2021), ELIFE, 10, e67852

DOI: 10.7554/eLife.67852

Evolution and genomic insight into methicillin-resistant Staphylococcus aureus ST9 in China

Jiang, Nansong; Wyres, Kelly L.; Li, Jun; Feßler, Andrea T.; Krüger, Henrike; Wang, Yang; Holt, Kathryn E.; Schwarz, Stefan; Wu, Congming

(2021), J ANTIMICROB CHEMOTH, 76(7), 1703-1711

DOI: 10.1093/jac/dkab106

Genomic adaptations to an endolithic lifestyle in the coral-associated alga Ostreobium

Iha, Cintia; Dougan, Katherine E.; Varela, Javier A.; Avila, Viridiana; Jackson, Christopher J.; Bogaert, Kenny A.; Chen, Yibi; Judd, Louise M.; Wick, Ryan; Holt, Kathryn E.; Pasella, Marisa M.; Ricci, Francesco; Repetti, Sonja I.; Medina, Mónica; Marceli

(2021), CURR BIOL, 31(7), 1393-1402e5

DOI: 10.1016/j.cub.2021.01.018

Performance of a hospital-acquired complication algorithm using administrative data for detection of central line-associated bloodstream infections

Herson, M.; Curtis, S. J.; Land, G.; Stewardson, A. J.; Worth, L. J.

(2021), J HOSP INFECT, 112, 116-118

DOI: 10.1016/j.jhin.2021.03.029

Global population structure and genotyping framework for genomic surveillance of the major dysentery pathogen, Shigella sonnei

Hawkey, Jane; Paranagama, Kalani; Baker, Kate S.; Bengtsson, Rebecca J.; Weill, François Xavier; Thomson, Nicholas R.; Baker, Stephen; Cerdeira, Louise; Iqbal, Zamin; Hunt, Martin; Ingle, Danielle J.; Dallman, Timothy J.; Jenkins, Claire; Williamson, Debo

(2021), NAT COMMUN, 12(1), 2684

DOI: 10.1038/s41467-021-22700-4

BonA from Acinetobacter baumannii forms a divisome-localized decamer that supports outer envelope function

Grinter, Rhys; Morris, Faye C.; Dunstan, Rhys A.; Leung, Pok Man; Kropp, Ashleigh; Belousoff, Matthew; Gunasinghe, Sachith D.; Scott, Nichollas E.; Beckham, Simone; Peleg, Anton Y.; Greening, Chris; Li, Jian; Heinz, Eva; Lithgow, Trevor

(2021), MBIO, 12(4), e01480-21

DOI: 10.1128/mBio.01480-21

Clinical Outcomes of 2-Drug Regimens vs 3-Drug Regimens in Antiretroviral Treatment-Experienced People Living With Human Immunodeficiency Virus

Greenberg, Lauren; Ryom, Lene; Neesgaard, Bastian; Wandeler, Gilles; Staub, Therese; Gisinger, Martin; Skoll, Michael; Günthard, Huldrych F.; Scherrer, Alexandra; Mussini, Cristina; Smith, Colette; Johnson, Margaret; De Wit, Stéphane; Necsoi, Coca; Pradie

(2021), CLIN INFECT DIS, 73(7), e2323-e2333

DOI: 10.1093/cid/ciaa1878

Characteristics of Agreements to have Condomless Anal Intercourse in the Presence of an Undetectable Viral Load Among HIV Serodiscordant Male Couples in Australia, Brazil and Thailand

Gray, James; Prestage, Garrett; Jin, Fengyi; Phanuphak, Nittaya; Friedman, Ruth K.; Fairley, Christopher K.; Kelleher, Anthony; Templeton, David; Zablotska-Manos, Iryna; Hoy, Jennifer; McNulty, Anna; Pell, Catherine; Grulich, Andrew; Bavinton, Benjamin; Z

(2021), AIDS BEHAV, 25(12), 3944-3954

DOI: 10.1007/s10461-021-03324-7

Bacteriophage-resistant Acinetobacter baumannii are resensitized to antimicrobials

Gordillo Altamirano, Fernando; Forsyth, John H.; Patwa, Ruzeen; Kostoulias, Xenia; Trim, Michael; Subedi, Dinesh; Archer, Stuart K.; Morris, Faye C.; Oliveira, Cody; Kielty, Luisa; Korneev, Denis; O’Bryan, Moira K.; Lithgow, Trevor J.; Peleg, Anton Y.; Ba

(2021), NAT MICROBIOL, 6(2), 157-161

DOI: 10.1038/s41564-020-00830-7

Detection of plasmid contigs in draft genome assemblies using customized Kraken databases

Gomi, Ryota; Wyres, Kelly L.; Holt, Kathryn E.

(2021), MICROBIOL GENOMICS, 7(4), 550

DOI: 10.1099/mgen.0.000550

Stealth nanorods via the aqueous living crystallisation-driven self-assembly of poly(2-oxazoline)s

Finnegan, John R.; Pilkington, Emily H.; Alt, Karen; Rahim, Md Arifur; Kent, Stephen J.; Davis, Thomas P.; Kempe, Kristian

(2021), CHEM SCI, 12(21), 7350-7360

DOI: 10.1039/d1sc00938a

Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance

Fareh, Mohamed; Zhao, Wei; Hu, Wenxin; Casan, Joshua M.L.; Kumar, Amit; Symons, Jori; Zerbato, Jennifer M.; Fong, Danielle; Voskoboinik, Ilia; Ekert, Paul G.; Rudraraju, Rajeev; Purcell, Damian F.J.; Lewin, Sharon R.; Trapani, Joseph A.

(2021), NAT COMMUN, 12(1), 4270

DOI: 10.1038/s41467-021-24577-9

Five Years of GenoTyphi: Updates to the Global Salmonella Typhi Genotyping Framework

Dyson, Zoe A.; Holt, Kathryn E.

(2021), J INFECT DIS, 224(7), S775-S780

DOI: 10.1093/infdis/jiab414

HIV is associated with an increased risk of age-related clonal hematopoiesis among older adults

Dharan, Nila J.; Yeh, Paul; Bloch, Mark; Yeung, Miriam M.; Baker, David; Guinto, Jerick; Roth, Norman; Ftouni, Sarah; Ognenovska, Katherine; Smith, Don; Hoy, Jennifer F.; Woolley, Ian; Pell, Catherine; Templeton, David J.; Fraser, Neil; Rose, Nectarios; H

(2021), NAT MED, 27(6), 1006-1011

DOI: 10.1038/s41591-021-01357-y

wMel Wolbachia genome remains stable after 7 years in Australian Aedes aegypti field populations

Dainty, Kimberley R.; Hawkey, Jane; Judd, Louise M.; Pacidônio, Etiene C.; Duyvestyn, Johanna M.; Gonçalves, Daniela S.; Lin, Silk Yu; O'Donnell, Tanya B.; O'Neill, Scott L.; Simmons, Cameron P.; Holt, Kathryn E.; Flores, Heather A.

(2021), MICROBIOL GENOMICS, 7(9), 641

DOI: 10.1099/mgen.0.000641

Pandora: nucleotide-resolution bacterial pan-genomics with reference graphs

Colquhoun, Rachel M.; Hall, Michael B.; Lima, Leandro; Roberts, Leah W.; Malone, Kerri M.; Hunt, Martin; Letcher, Brice; Hawkey, Jane; George, Sophie; Pankhurst, Louise; Iqbal, Zamin

(2021), GENOME BIOL, 22(1), 267

DOI: 10.1186/s13059-021-02473-1