Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Rhenium and technetium complexes that bind to amyloid-β plaques

Hayne DJ, North AJ, Fodero-Tavoletti M, White JM, Hung LW, Rigopoulos A, McLean CA, Adlard PA, Ackermann U, Tochon-Danguy H, Villemagne VL, Barnham KJ, Donnelly PS

(2015), Dalton Trans, 44(11), 4933-44

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1

Glubb DM, Maranian MJ, Michailidou K, Pooley KA, Meyer KB, Kar S, Carlebur S, O'Reilly M, Betts JA, Hillman KM, Kaufmann S, Beesley J, Canisius S, Hopper JL, Southey MC, Tsimiklis H, Apicella C, Schmidt MK, Broeks A, Hogervorst FB, van der Schoot CE, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Ruebner M, Ekici AB, Beckmann MW, Peto J, dos-Santos-Silva I, Fletcher O, Johnson N, Pharoah PD, Bolla MK, Wang Q, Dennis J, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Burwinkel B, Marme F, Yang R, Surowy H, Guénel P, Truong T, Menegaux F, Sanchez M, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, González-Neira A, Benitez J, Zamora MP, Arias Perez JI, Anton-Culver H, Neuhausen SL, Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, Meindl A, Schmutzler RK, Brauch H, Ko YD, Brüning T; GENICA Network, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Matsuo K, Ito H, Iwata H, Tanaka H, DÖrk T, Bogdanova NV, Helbig S, Lindblom A, Margolin S, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM; kConFab Investigators, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Lambrechts D, Zhao H, Weltens C, van Limbergen E, Chang-Claude J, Flesch-Janys D, Rudolph A, Seibold P, Radice P, Peterlongo P, Barile M, Capra F, Couch FJ, Olson JE, Hallberg E, Vachon C, Giles GG, Milne RL, McLean C, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Simard J, Goldberg MS, Labrèche F, Dumont M, Teo SH, Yip CH, See MH, Cornes B, Cheng CY, Ikram MK, Kristensen V; Norwegian Breast Cancer Study, Zheng W, Halverson SL, Shrubsole M, Long J, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Kauppila S, Andrulis IL, Knight JA, Glendon G, Tchatchou S, Devilee P, Tollenaar RA, Seynaeve C, Van Asperen CJ, García-Closas M, Figueroa J, Chanock SJ, Lissowska J, Czene K, Klevebring D, Darabi H, Eriksson M, Hooning MJ, Hollestelle A, Martens JW, Collée JM, Hall P, Li J, Humphreys K, Shu XO, Lu W, Gao YT, Cai H, Cox A, Cross SS, Reed MW, Blot W, Signorello LB, Cai Q, Shah M, Ghoussaini M, Kang D, Choi JY, Park SK, Noh DY, Hartman M, Miao H, Lim WY, Tang A, Hamann U, Torres D, Jakubowska A, Lubinski J, Jaworska K, Durda K, Sangrajrang S, Gaborieau V, Brennan P, McKay J, Olswold C, Slager S, Toland AE, Yannoukakos D, Shen CY, Wu PE, Yu JC, Hou MF, Swerdlow A, Ashworth A, Orr N, Jones M, Pita G, Alonso MR, Álvarez N, Herrero D, Tessier DC, Vincent D, Bacot F, Luccarini C, Baynes C, Ahmed S, Healey CS, Brown MA, Ponder BA, Chenevix-Trench G, Thompson DJ, Edwards SL, Easton DF, Dunning AM, French JD

(2015), Am J Hum Genet, 96(1), 5-20

Postexcisional melanocytic regrowth extending beyond the initial scar: a novel clinical sign of melanoma

Kelly JW, Shen S, Pan Y, Dowling J, McLean CA

(2014), Br J Dermatol, 170(4), 961-4

Neuropathology training worldwide-evolution and comparisons

Del Bigio MR, Hainfellner JA, McLean CA, Powell SZ, Sikorska B, Takahashi H, Weis J, Xuereb JH

(2014), Brain Pathol, 24(3), 285-98

Diagnostic accuracy of malignant melanoma according to subtype

Lin MJ, Mar V, McLean C, Wolfe R, Kelly JW

(2014), Australas J Dermatol, 55(1), 35-42

Bright muscle, weak heart, bad start?

Jaworski C, Looi JL, Iles LM, McLean CA, Taylor AJ, Hare JL

(2014), Heart Lung Circ, 23(3), 293-4

Fine-needle aspiration of the thyroid: correlating suspicious cytology results with histological outcomes

Baynes AL, Del Rio A, McLean C, Grodski S, Yeung MJ, Johnson WR, Serpell JW

(2014), Ann Surg Oncol, 21(5), 1653-8

TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions

Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, Frosch MP, Alafuzoff I, Antonell A, Bogdanovic N, Brooks W, Cairns NJ, Cooper-

(2014), Acta Neuropathol, 127(3), 407-18

Ceruloplasmin and β-amyloid precursor protein confer neuroprotection in traumatic brain injury and lower neuronal iron

Ayton S, Zhang M, Roberts BR, Lam LQ, Lind M, McLean C, Bush AI, Frugier T, Crack PJ, Duce JA

(2014), Free Radic Biol Med, 69, 331-7

Assessing THK523 selectivity for tau deposits in Alzheimer's disease and non-Alzheimer's disease tauopathies

Fodero-Tavoletti MT, Furumoto S, Taylor L, McLean CA, Mulligan RS, Birchall I, Harada R, Masters CL, Yanai K, Kudo Y, Rowe CC, Okamura N, Villemagne VL

(2014), Alzheimers Res Ther, 6(1), 11

Detectable CD8 cells correlate with improved overall survival in adult B lymphoblastic leukaemia patients

Low M, Lee D, McLean C, Nguyen T, Morgan S, Grigoriadis G

(2014), Br J Haematol, 165(6), 883-5

Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain

Lim NK, Hung LW, Pang TY, Mclean CA, Liddell JR, Hilton JB, Li QX, White AR, Hannan AJ, Crouch PJ

(2014), Hum Mol Genet, 23(15), 4051-63

Idiopathic granulomatous hypophysitis: comments and a disease registry

Hunn BH, Martin WG, McLean CA

(2014), J Clin Neurosci, 21(5), 891

Decreased serum zinc is an effect of ageing and not Alzheimer's disease

Rembach A, Hare DJ, Doecke JD, Burnham SC, Volitakis I, Fowler CJ, Cherny RA, McLean C, Grimm R, Martins R, Ames D, Masters CL, Bush AI, Roberts BR

(2014), Metallomics, 6(7), 1216-9

Genetic predisposition to in situ and invasive lobular carcinoma of the breast

Sawyer E, Roylance R, Petridis C, Brook MN, Nowinski S, Papouli E, Fletcher O, Pinder S, Hanby A, Kohut K, Gorman P, Caneppele M, Peto J, Dos Santos Silva I, Johnson N, Swann R, Dwek M, Perkins KA, Gillett C, Houlston R, Ross G, De Ieso P, Southey MC, Hop

(2014), PLoS Genet, 10(4), e1004285

Do current therapeutic anti-Aβ antibodies for Alzheimer's disease engage the target?

Watt AD, Crespi GA, Down RA, Ascher DB, Gunn A, Perez KA, McLean CA, Villemagne VL, Parker MW, Barnham KJ, Miles LA

(2014), Acta Neuropathol, 127(6), 803-10

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade

Purrington KS, Slettedahl S, Bolla MK, Michailidou K, Czene K, Nevanlinna H, Bojesen SE, Andrulis IL, Cox A, Hall P, Carpenter J, Yannoukakos D, Haiman CA, Fasching PA, Mannermaa A, Winqvist R, Brenner H, Lindblom A, Chenevix-Trench G, Benitez J, Swerdlow

(2014), Hum Mol Genet, 23(22), 6034-46

An objective measure of growth rate using partial biopsy specimens of melanomas that were initially misdiagnosed

Lin MJ, Mar V, McLean C, Kelly JW

(2014), J Am Acad Dermatol, 71(4), 691-7

Clinical and pathological associations of the activating RAC1 P29S mutation in primary cutaneous melanoma

Mar VJ, Wong SQ, Logan A, Nguyen T, Cebon J, Kelly JW, Wolfe R, Dobrovic A, McLean C, McArthur GA

(2014), Pigment Cell Melanoma Res, 27(6), 1117-25

Anti-Aβ antibody target engagement: a response to Siemers et al

Watt AD, Crespi GA, Down RA, Ascher DB, Gunn A, Perez KA, McLean CA, Villemagne VL, Parker MW, Barnham KJ, Miles LA

(2014), Acta Neuropathol, 128(4), 611-4