Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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In vitro neurons learn and exhibit sentience when embodied in a simulated game-world

Kitchen, Andy C; Kagan, Brett J; Tran, Nhi T; Habibollahi, Forough; Khajehnejad, Moein; Parker, Bradyn J; Bhat, Anjali; Rollo, Ben; Razi, Adeel; Friston, Karl J

(2022), NEURON, 110

DOI: 10.1016/j.neuron.2022.09.001

Overview of the clinical approach to individuals with cerebellar ataxia and neuropathy

Roberts, Leslie J; McVeigh, Michael; Seiderer, Linda; Harding, Ian H; Corben, Louise A; Delatycki, Martin; Szmulewicz, David J

(2022), NEUROL-GENET, 8(5), e200021

DOI: 10.1212/NXG.0000000000200021

Leveraging Visual Outcome Measures to Advance Therapy Development in Neuroimmunologic Disorders

Graves, Jennifer S; Oertel, Frederike Cosima; Van der Walt, Anneke; Collorone, Sara; Sotirchos, Elias S; Pihl-Jensen, Gorm; Albrecht, Philipp; Yeh, E Ann; Saidha, Shiv; Frederiksen, Jette; Newsome, Scott Douglas; Paul, Friedemann; ,

(2022), NEUROL-NEUROIMMUNOL, 9(2), e1126

DOI: 10.1212/NXI.0000000000001126

Somatic Mosaic Pathogenic Variant Gradient Detected in Trace Brain Tissue from Stereo-EEG Depth Electrodes

Ye, Zimeng; Bennett, Mark F; Neal, Andrew; Laing, Joshua A; Hunn, Martin K; Wittayacharoenpong, Thanomporn; Todaro, Marian; Patel, Sheila K; Bahlo, Melanie; Kwan, Patrick; O'Brien, Terence J; Scheffer, Ingrid E; Berkovic, Samuel F; Perucca, Piero;

(2022), NEUROLOGY, 99(23), 1036-1041

DOI: 10.1212/WNL.0000000000201469

Association of Latitude and Exposure to Ultraviolet B Radiation With Severity of Multiple Sclerosis

Vitkova, Marianna; Diouf, Ibrahima; Malpas, Charles; Horakova, Dana; Kubala Havrdova, Eva; Patti, Francesco; Ozakbas, Serkan; Izquierdo, Guillermo; Eichau, Sara; Shaygannejad, Vahid; Onofrj, Marco; Lugaresi, Alessandra; Alroughani, Raed; Prat, Alexandre;

(2022), NEUROLOGY, 98(24), e2401-e2412

DOI: 10.1212/WNL.0000000000200545

Seizure Outcome After Surgery for MRI-Diagnosed Focal Cortical Dysplasia

Willard, Anna; Antonic-Baker, Ana; Chen, Zhibin; O'Brien, Terence John; Kwan, Patrick; Perucca, Piero

(2022), NEUROLOGY, 98(3), e236-e248

DOI: 10.1212/WNL.0000000000013066

Safety and Efficacy of Tenecteplase in Older Patients with Large Vessel Occlusion

Yogendrakumar, Vignan; Churilov, Leonid; Mitchell, Peter J; Kleinig, Timothy J; Yassi, Nawaf; Thijs, Vincent; Wu, Teddy Y; Shah, Darshan G; Ng, Felix C; Dewey, Helen M; Wijeratne, Tissa; Yan, Bernard; Desmond, Patricia M; Parsons, Mark W; Donnan,

(2022), NEUROLOGY, 98(12), E1292-E1301

DOI: 10.1212/WNL.0000000000013302

Serious Cardiac Arrhythmias Detected by Subcutaneous Long-term Cardiac Monitors in Patients With Drug-Resistant Epilepsy

Sivathamboo, Shobi; Liu, Zining; Sutherland, Fiona; Minato, Erica; Casillas-Espinosa, Pablo; Jones, Nigel Charles; Todaro, Marian; Seneviratne, Udaya; Cahill, Varduhi; Yerra, Raju; French, Christopher R; Nicolo, John-Paul; Perucca, Piero; Kwan, Patrick;

(2022), NEUROLOGY, 98(19), e1923-e1932

DOI: 10.1212/WNL.0000000000200173

Early and progressive dysfunction revealed by in vivo neurite imaging in the rNLS8 TDP-43 mouse model of ALS

Zamani, Akram; Walker, Adam K; Rollo, Ben; Ayers, Katie L; Farah, Raysha; O'Brien, Terence J; Wright, David K

(2022), NEUROIMAGE-CLIN, 34, 103016

DOI: 10.1016/j.nicl.2022.103016

Brain tissue microstructural and free-water composition 13 years after very preterm birth

Kelly, Claire; Dhollander, Thijs; Harding, Ian H; Khan, Wasim; Beare, Richard; Cheong, Jeanie LY; Doyle, Lex W; Seal, Marc; Thompson, Deanne K; Inder, Terrie E; Anderson, Peter J

(2022), NEUROIMAGE, 254, 119168

DOI: 10.1016/j.neuroimage.2022.119168

Cortical thinning 3 years after ischaemic stroke is associated with cognitive impairment and APOE e4

Salah Khlif, Mohamed; Egorova-Brumley, Natalia; Bird, Laura J; Werden, Emilio; Brodtmann, Amy

(2022), NEUROIMAGE-CLIN, 36, 103200

DOI: 10.1016/j.nicl.2022.103200

Characterising seizure development, behavioural comorbidities and neuroinflammation in a self-sustained electrical status epilepticus model of mesial temporal lobe epilepsy in C57BL/6J mice

Thergarajan, Peravina; Hudson, Matthew R; Carmichael, Irena; Clasadonte, Jérôme; Dedeurwaerdere, Stefanie; O'Brien, Terence J; Jones, Nigel C; Ali, Idrish

(2022), NEUROBIOL DIS, 168, 105688

DOI: 10.1016/j.nbd.2022.105688

Treatment with Multiple Therapeutic Classes of Medication Is Associated with Survival after Stroke

Kilkenny, Monique F; Olaiya, Muideen T; Dalli, Lachlan L; Kim, Joosup; Andrew, Nadine E; Sanfilippo, Frank M; Thrift, Amanda G; Nelson, Mark; Pearce, Christopher; Sanders, Lauren; Dewey, Helen; Clissold, Benjamin; Grimley, Rohan; Cadilhac, Dominique

(2022), NEUROEPIDEMIOLOGY, 56(1), 66-74

DOI: 10.1159/000520823

Interictal and seizure-onset EEG patterns in malformations of cortical development: A systematic review

Shakhatreh, Lubna; Janmohamed, Mubeen; Baker, Ana Antonic; Willard, Anna; Laing, Joshua; Rychkova, Maria; Chen, Zhibin; Kwan, Patrick; O'Brien, Terence J; Perucca, Piero

(2022), NEUROBIOL DIS, 174, 105863

DOI: 10.1016/j.nbd.2022.105863

Hypothalamic effective connectivity at rest is associated with body weight and energy homeostasis

Voigt, Katharina; Andrews, Zane B; Harding, Ian H; Razi, Adeel; Verdejo-García, Antonio

(2022), NETW NEUROSCI, 6(4), 1316-1333

DOI: 10.1162/netn_a_00266

Establishment and recall of SARS-CoV-2 spike epitope-specific CD4+ T cell memory

Wragg, Kathleen M; Lee, Wen Shi; Koutsakos, Marios; Tan, Hyon-Xhi; Amarasena, Thakshila; Reynaldi, Arnold; Gare, Grace; Konstandopoulos, Penny; Field, Kirsty R; Esterbauer, Robyn; Kent, Helen E; Davenport, Miles P; Wheatley, Adam K; Kent, Stephen J;

(2022), NAT IMMUNOL, 23(5), 768-780

DOI: 10.1038/s41590-022-01175-5

Disentangling the relative importance of T cell responses in COVID-19

Kent, Stephen J; Khoury, David S; Reynaldi, Arnold; Juno, Jennifer A; Wheatley, Adam K; Stadler, Eva; John Wherry, E; Triccas, James; Sasson, Sarah C; Cromer, Deborah; Davenport, Miles P

(2022), NAT REV IMMUNOL, 22(6), 387-397

DOI: 10.1038/s41577-022-00716-1

Time is of the essence for vaccine success

Quast, Isaak; Tarlinton, David

(2022), NAT IMMUNOL, 23(11), 1517–1519

DOI: 10.1038/s41590-022-01347-3

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection

Phetsouphanh, Chansavath; Darley, David R; Wilson, Daniel B; Howe, Annett; Munier, C Mee Ling; Patel, Sheila K; Juno, Jennifer A; Burrell, Louise M; Kent, Stephen J; Dore, Gregory J; Kelleher, Anthony D; Matthews, Gail V

(2022), NAT IMMUNOL, 23(2), 210-216

DOI: 10.1038/s41590-021-01113-x

Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection

Di Pietro, Andrea; Polmear, Jack; Cooper, Lucy; Damelang, Timon; Hussain, Tabinda; Hailes, Lauren; O’Donnell, Kristy; Udupa, Vibha; Mi, Tian; Preston, Simon; Shtewe, Areen; Hershberg, Uri; Turner, Stephen J; La Gruta, Nicole L; Chung, Amy W; Tarlinton,

(2022), NAT IMMUNOL, 23(1), 86-98

DOI: 10.1038/s41590-021-01077-y

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