Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Muscarinic receptor binding changes in postmortem Parkinson's disease

McOmish C, Pavey G, McLean C, Horne M, Dean B, Scarr E

(2017), J Neural Transm, 124(2), 227-36

DOI: 10.1007/s00702-016-1629-z

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, Murray ME, Nelson PT, Takahashi H, Trojanowski JQ, Ansorge O, Arzberger T, Baborie A,

(2016), Acta Neuropathol, 131(1)

Hepatocyte glutathione peroxidase-1 deficiency improves hepatic glucose metabolism and decreases steatohepatitis in mice

Merry TL, Tran M, Dodd GT, Mangiafico SP, Wiede F, Kaur S, McLean CL, Andrikopoulos S, Tiganis T

(2016), Diabetologia, 59(12)

Ten year clinical experience with stroke and cerebral vasculitis

Kempster PA, McLean CA, Phan TG

(2016), J Clin Neurosci, 27

A gallium(III) Schiff base-curcumin complex that binds to amyloid-β plaques

Lange JL, Hayne DJ, Roselt P, McLean CA, White JM, Donnelly PS

(2016), J Inorg Biochem, 162

Evidence for the recruitment of autophagic vesicles in human brain after stroke

Frugier T, Taylor JM, McLean C, Bye N, Beart PM, Devenish RJ, Crack PJ

(2016), Neurochem Int, 96

Association between discoid lupus erythematosus and chronic granulomatous disease--report of two cases and review of the literature

Xie C, Cole T, McLean C, Su JC

(2016), Pediatr Dermatol, 33(2)

The NF-ΚB transcription factor RelA is required for the tolerogenic function of Foxp3(+) regulatory T cells

Messina N, Fulford T, O'Reilly L, Loh WX, Motyer JM, Ellis D, McLean C, Naeem H, Lin A, Gugasyan R, Slattery RM, Grumont RJ, Gerondakis S

(2016), J Autoimmun, 70

Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer

Shi J, Zhang Y, Zheng W, Michailidou K, Ghoussaini M, Bolla MK, Wang Q, Dennis J, Lush M, Milne RL, Shu XO, Beesley J, Kar S, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Zhao Z, Guo X, Benitez J, Beeghly-Fadiel A, Blot W, Bogdanova NV, Bojesen SE,

(2016), Int J Cancer, 139(6)

microRNA profiling: increased expression of miR-147a and miR-518e in progressive supranuclear palsy (PSP)

Tatura R, Buchholz M, Dickson DW, van Swieten J, McLean C, HÖglinger G, Müller U

(2016), Neurogenetics, 17(3)

Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry

Zhao Z, Wen W, Michailidou K, Bolla MK, Wang Q, Zhang B, Long J, Shu XO, Schmidt MK, Milne RL, García-Closas M, Chang-Claude J, Lindstrom S, Bojesen SE, Ahsan H, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Beeghly-Fadiel A, Benitez J,

(2016), Cancer Causes Control, 27(5)

Laser ablation-inductively coupled plasma-mass spectrometry imaging of white and gray matter iron distribution in Alzheimer's disease frontal cortex

Hare DJ, Raven EP, Roberts BR, Bogeski M, Portbury SD, McLean CA, Masters CL, Connor JR, Bush AI, Crouch PJ, Doble PA

(2016), Neuroimage, 137

Pathogenic upregulation of glial lipocalin-2 in the Parkinsonian dopaminergic system

Kim BW, Jeong KH, Kim JH, Jin M, Kim JH, Lee MG, Choi DK, Won SY, McLean C, Jeon MT, Lee HW, Kim SR, Suk K

(2016), J Neurosci, 36(20)

LGI1 antibody encephalopathy overlapping with sporadic Creutzfeldt-Jakob disease

Kim B, Yoo P, Sutherland T, Boyd A, Stehmann C, McLean C, Collins S

(2016), Neurol Neuroimmunol Neuroinflamm, 3(4)

Severe left ventricular hypertrophy and marked cardiac fibrosis in Danon disease

Stokes MB, Taylor AJ, McLean CA, D'Arcy CE, Mariani JA

(2016), Int J Cardiol, 221

Genome-wide meta-analyses of breast, ovarian, and prostate cancer association studies identify multiple new susceptibility loci shared by at least two cancer types

Kar SP, Beesley J, Amin Al Olama A, Michailidou K, Tyrer J, Kote-Jarai Z, Lawrenson K, Lindstrom S, Ramus SJ, Thompson DJ; ABCTB Investigators., Kibel AS, Dansonka-Mieszkowska A, Michael A, Dieffenbach AK, Gentry-Maharaj A, Whittemore AS, Wolk A, Monteiro

(2016), Cancer Discov, 6(9)

Synthesis of Oxorhenium(V) and Oxotechnetium(V) complexes that bind to amyloid-β plaques

Hayne DJ, White JM, McLean CA1, Villemagne VL, Barnham KJ, Donnelly PS

(2016), Inorg Chem, 55(16)

Genetically predicted Body Mass Index and breast cancer risk: Mendelian randomization analyses of data from 145,000 women of European descent

Guo Y, Warren Andersen S, Shu XO, Michailidou K, Bolla MK, Wang Q, Garcia-Closas M, Milne RL, Schmidt MK, Chang-Claude J, Dunning A, Bojesen SE, Ahsan H, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bogdanov

(2016), PLoS Med, 13(8)

Transferrin protects against Parkinsonian neurotoxicity and is deficient in Parkinson’s substantia nigra

Ayton S, Lei P, McLean C, Bush AI, Finkelstein DI

(2016), Signal Transduct Targeted Ther, 1(2016)

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

Southey MC, Goldgar DE, Winqvist R, Pylkäs K, Couch F, Tischkowitz M, Foulkes WD, Dennis J, Michailidou K, van Rensburg EJ, Heikkinen T, Nevanlinna H, Hopper JL, DÖrk T, Claes KB, Reis-Filho J, Teo ZL, Radice P, Catucci I, Peterlongo P, Tsimiklis H, Odefr

(2016), J Med Genet, 53(12)

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