Clinical electrophysiology research

The Electrophysiology research group, headed by Professor Peter Kistler, are international leaders in the latest causes and treatments for heart rhythm disorders.

The group closely collaborates with teams across the country and internationally in the USA, UK and Canada to complete clinical trials furthering our understanding and treatments for heart rhythm disorders, in particular atrial fibrillation (AF).

Research focus

At the Alfred, we pioneered the role of catheter ablation for atrial fibrillation in heart failure leading to a paradigm shift in the management of these common conditions. We published the first trial exploring the role of alcohol in atrial fibrillation in the New England Journal. We are at the forefront of understanding the mechanisms responsible for heart rhythm disorders tailoring ablation strategies accordingly.

Prof Peter Kistler

Professor Peter Kistler is a clinician cardiologist and electrophysiologist and an international leader in the treatment of heart rhythm disorders.

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A/Prof Liang-han Ling

A/Prof Ling is a cardiologist at The Alfred.

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A/Prof Sandeep (Sunny) Prabhu

Associate Professor Sandeep Prabhu (Sunny) is a cardiologist and interventional electrophysiologist specialising in the management of cardiac rhythm disorders.

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A/Prof Aleksandr Voskoboinik

Alex Voskoboinik is a Cardiologist and Electrophysiologist.

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Dr David Chieng

Dr David Chieng is a consultant cardiologist and electrophysiologist who specializes in the management of heart rhythm disturbances, including cardiac arrhythmia ablation (SVT, Atrial fibrillation, atrial flutter, ventricular tachycardia) and cardiac device implantation (pacemaker, defibrillator, cardiac resynchronization therapy).

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Dr Hariharan Sugumar

Dr Hari Sugumar is a specialist cardiologist and electrophysiologist.

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Ms Sonia Azzopardi

Ms Sonia Azzopardi is an experienced cardiac Clinical Nurse Consultant and Research Coordinator, specialising in Arrhythmia.

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Dr Louise Segan

Dr Louise Segan is a consultant cardiologist and clinical electrophysiologist at The Alfred who specialises in management of heart rhythm disorders including cardiac device implantation and monitoring and ablation procedures.

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Current trials open to enrolments

The Yoga-AF study is a world-first randomised trial exploring the role of yoga in heart disease, in this case, AF.

The Endure-AF study compares two different approaches to AF ablation techniques in people who require a redo AF ablation procedure for recurrent AF.

Other trials examine outcomes of AF ablation in patients with enduring pulmonary vein isolation and patterns of pulmonary vein reconnection in the era of pulsed field ablation (PFA).

Commercially sponsored trials, ReMATCH and CathRx Electropulse evaluate the effectiveness of catheters for PFA.

A/Prof Sandeep Prabhu has ongoing studies in the role of catheter ablation and heart failure. A/Prof Alex Voskoboinik is exploring the most effective strategies for patients with recurrent loss of consciousness (SYNCOPE STOPPER) and improving outcomes in cardiac arrest. We have ongoing studies pioneering approaches and technologies in catheter ablation for atrial fibrillation.

Find out more about Clinical Electrophysiology laboratory research conducted at the Baker Heart & Diabetes Institute.

Publications

Impaired Oxygen Uptake Recovery Is Associated With Disease Severity In Systemic Sclerosis.

Anniina Lindqvist, Laura Ross, Ben Costello, Warren Perera, Marcus Pianta, Kristel Janssens, Amy Mitchell, Zoe Brown, Wendy Stevens, Andrew Burns, David Prior, Mandana Nikpour, Kegan J Moneghetti, Andre La Gerche

(2023), MEDICINE & SCIENCE IN SPORTS & EXERCISE, 55, 144-145

DOI: 10.1249/01.mss.0000981068.81091.ec

Atrial Fibrillation Ablation for Heart Failure With Preserved Ejection Fraction: A Randomized Controlled Trial.

David Chieng, Hariharan Sugumar, Louise Segan, Caleb Tan, Donna Vizi, Shane Nanayakkara, Ahmed Al-Kaisey, Joshua Hawson, Sandeep Prabhu, Aleksandr Voskoboinik, Sue Finch, Joseph B Morton, Geoffrey Lee, Justin Mariani, Andre La Gerche, Andrew J Taylor, Erin Howden, Peter M Kistler, Jonathan M Kalman, David M Kaye, Liang-Han Ling

(2023), JACC-HEART FAILURE, 6(11), 646-58

DOI: 10.1016/j.jchf.2023.01.008

Chest Pain Management Using Prehospital Point-of-Care Troponin and Paramedic Risk Assessment

Dawson, Luke Peter; Nehme, Emily Patricia; Nehme, Ziad; Zomer, Ella; Bloom, Jason Elliott; Cox, Shelley; Anderson, David John; Stephenson, Michael William; Ball, Jocasta Clare; Zhou, Jennifer Y.; Lefkovits, Jeffrey; Taylor, Andrew; Horrigan, M; Chew, Dere

(2023), JAMA Internal Medicine, 183, 203-211

DOI: 10.1001/jamainternmed.2022.6409

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