Heart preservation for transplantation
An organ preservation project led by Professor Frank Rosenfeldt will assess a new, improved technique of donor heart preservation based on cold crystalloid microperfusion.
It is hoped that this will improve preservation, particularly of long ischemic time organs, and may also have a role in the preservation of ‘donation after circulatory death’ hearts.
A great deal of work has gone into improving the technology of the transport and preservation system for these hearts and further animal experiments to validate the system are planned for 2015. Professor David McGiffin is collaborating with Professor John Fraser from Prince Charles Hospital, Queensland, on a donor heart preservation project. Detailed experiments involving heart transplants in large animals will be undertaken in Queensland.
Professor McGiffin (CIB) and Professor Fraser (CIA) have secured an NHMRC grant of $2.5 million for the Centre for Research Excellence in Advanced Cardiorespiratory Therapies Improving OrgaN Support (ACTIONS).