A Randomized, Double-Blind, Phase 3 Study of Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D–Mutated Metastatic Pancreatic Ductal Adenocarcinoma [DAWN-303] (NCT07522073)

INCB161734-303 / DAWN-303

This trial is Currently recruiting
Registration number NCT07522073
The purpose of this study is to evaluate the efficacy and safety of standard chemotherapy with or without INCB161734 in participants with metastatic pancreatic ductal adenocarcinoma (PDAC).

Program & service

This trial is being run with the Cancer service, and as part of the Medical Oncology program.

Trial phase

Phase 3

Trial participation type

This trial has been designed for the Clinical Research of a Drug.

Principal investigator

Dr Ben Markman

Key inclusion data

Histologically or cytologically confirmed metastatic adenocarcinoma of the pancreas (PDAC) with a KRAS G12D mutation. ECOG Performance status 0 or 1. No prior systemic treatment for metastatic PDAC. No prior treatment with any KRAS inhibitor. No known active CNS metastases.

More information

To find out more about this clinical trial, please review full details on the ANZCTR website.

View on ANZCTR

If you would like further details or have any questions about this clinical trial, we encourage you to get in touch with us and a member of our team will be happy to provide you with more information.

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