A/Prof Shaun Fleming
Shaun is a clinical and laboratory haematologist, head of the myeloid disease program at Alfred Health and a conjoint associate professor at the Australian Centre for Blood Diseases at Monash University.
Shaun has a particular interest in the treatment of acute leukaemia, application of cellular therapies such as chimeric antigen receptor T-cells in acute leukaemia and in the use of prognostication strategies including machine learning and measurable residual disease testing.
Through the Haematology Clinical Research Unit Shaun is principal investigator on several clinical trials in acute leukaemia and Myelodysplasia and has been the national coordinating investigator on the Australasian Leukaemia and Lymphoma Group ALL08 study. He is the current chair of the ALLG acute lymphoblastic leukaemia working party, the co-chair of the education committee of the Australian and New Zealand Transplant and Cellular Therapies Society and sits on the registry committee of that organisation.
Shaun has a research interest in the use of novel therapies in acute leukaemia, in particular immunotherapies such as bi-specifics and in the application of therapies to currently underserved patient populations. He supervises his fellows and graduate research students in clinical trial development, disease prognostication, and application of machine learning techniques. Through the haematology laboratory he has along with the scientific staff championed the development of new panels to track CART cells and monitor low level disease in acute lymphoblastic leukaemia.