General Surgery research

The General Surgery Department is committed to clinical and translational research, clinical trials and the development and maintenance of databases and clinical registries, including cancer related registries.

The Breast and Endocrine Surgery Unit undertakes research in the areas of breast cancer and endocrine surgery including thyroid, parathyroid and adrenal surgery.

The Upper Gastrointestinal (GI) Surgical Unit’s interests include outcomes of bariatric surgery, inflammatory effects of radical cancer surgery and the physiology of upper GI surgery.

Research activities of the Colorectal Surgical Unit relate to colorectal cancer (CRC) and the unit has commenced or completed projects in the areas of inflammatory bowel disease, novel surgical techniques and investigation of Clostridium difficile infection (CDI).

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Publications

Liver-Secreted Hexosaminidase A Regulates Insulin-Like Growth Factor Signaling and Glucose Transport in Skeletal Muscle

Montgomery, Magdalene; Bayliss, Jacqueline A.; Nie, Shuai; De Nardo, William; Keenan, Stacey N.; Anari, Marziyeh; Taddese, Amanuiel Z.; Williamson, Nicholas A.; Ooi, Geraldine Jia-Ping; Brown, Wendy Ann; Burton, Paul Robert; Gregorevic, Paul; Goodman, Cr

(2023), Diabetes, 72(6), 715-727

DOI: 10.2337/db22-0590

Malnutrition defined by GLIM criteria identifies a higher incidence of malnutrition and is associated with pulmonary complications after oesophagogastric cancer surgery, compared to ICD-10-defined malnutrition

Murnane, L. C., Forsyth, A. K., Koukounaras, J., Shaw, K., King, S., Brown, W. A., Mourtzakis, M., Tierney, A. C., & Burton, P. R

(2023), Journal of surgical oncology, 128(5), 769-80

DOI: 10.1002/jso.27366

Long-term impact of weight loss for people with overweight but not obesity, and with type 2 diabetes

Qi, Qi Yang Damien; Playfair, Julie Marie; Brown, Wendy Ann; Burton, Paul Robert; O'Brien, Paul Edmond; Wentworth, John

(2023), DIABETES OBESITY & METABOLISM, 25(6), 1464-1472

DOI: 10.1111/dom.14992

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