Radiation Oncology clinical trials

Alfred Health Radiation Oncology consults with patients on their cancer care and provides radiation therapy for patients who need it. In partnership with Monash University, we are active in clinical and preclinical trials. We participate in the full range of cancer trials, from basic biology, immunology, and physics, through to a range of clinical trials testing new treatments. 

male clinical trials patient in bed with a male nurse standing nearby with a syringe

Why are clinical trials so important?

We need clinical trials to prove that a new medication, device or treatment is safe and effective for people.

Without clinical trials, new treatments and medicines cannot be approved for use in Australia.

Find out more about clinical trials

About us

Alfred Health Radiation Oncology is an academic Monash University-associated department active in clinical and preclinical trials.

We co-ordinate closely with other Alfred Health services and with the regional cancer centre in Traralgon where we have a radiation oncology facility. This facility brings a unique regional perspective to clinical trials. 

Find out more about our Radiation Oncology service.

What are Phase I, II, III or IV clinical trials?

There are four different phases of a clinical trial. Each phase is represented by a roman numeral.

Find out more about what happens in each phase
Patient Peter with Prof Jeremy Millar and A/Prof Jeremy Grummet

Our vision

  • To promote, oversee, and complete scientific research in clinical radiation oncology - and directly-related basic-science and epidemiology - that leads to continued improvement in treatment delivery and better outcomes for patients we and others look after with radiation therapy.

Our focus

We participate in the full range of cancer trials, from basic biology, immunology, and physics, through to a range of clinical trials testing new treatments. 

Our specific areas of interest as outlined below.

Technical

  • Stereotactic treatments - brain and body
  • Surface guided radiation treatments
  • Brachytherapy

Disease sites

  • Prostate cancer
  • CNS
  • Melanoma
  • Lung

Regional oncology services

  • Health services research on delivery of high-quality cancer services, particularly radiation therapy services, in the regional Australian environment
  • Epidemiological research into the cancer problems in Australian regional geographies

Methodology

  • Multi-site clinical trials
  • Research using AHRO disease and treatment registry
  • Preclinical laboratory based translational research
     

Our achievements

  • We have decades of experience in stereotactic radiosurgery and radiotherapy and were the only Australian centre to recruit patients to the SABR-COMET study and accrued the first international patient to the SABR-COMET 3 study, two studies redefining the role of radiation therapy in cancer that has spread widely in the patient.
  • We were the first Novalis Certified Centre in Australia and New Zealand and were the first centre to install surface guided radiation therapy (SGRT) and to deliver tattoo and skin marks free treatment.  
  • We have an extensive prostate brachytherapy program with international collaborators in research.
     

Our team

Our Research Operations Group are leaders in their fields, with decades of Australian and international experience:

  • Prof Jeremy Millar, Director of Research
  • Mr Supun Hettige, Radiation Therapist
  • Dr Rohan Nair, Radiation Oncologist
  • Carole Owens, Clinical Trials Radiation Therapist
  • Dr Vanessa Panettieri, Medical Physicist
  • Robin Smith, Research Manager
  • Katrina Woodford, Radiation Therapist

Publications

Late, persistent, substantial treatment-related symptoms (LAPERS) following low-dose-rate brachytherapy for prostate cancer

Ong, Wee Loon; Millar, Jeremy Laurence

(2023), Brachytherapy, 22(4), 524-30

DOI: 10.1016/j.brachy.2023.01.001

Variation in patient reported outcomes following radical prostatectomy: A bi-national registry-based study

O'Callaghan ME, Roberts MJ, Moretti KL, Frydenberg M, Gilbourd D, Mark S, Heathcote P, Millar J, Pcor-Anz, Papa N

(2023), UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 41(2), 105.e-105.e18

DOI: 10.1016/j.urolonc.2022.10.020

Response to comment to “Dosimetric correlates of toxicities and quality of life following two-fraction stereotactic ablative radiotherapy (SABR) for prostate cancer”

Ong, Wee Loon; Zhang, Liying; Loblaw, Andrew

(2023), Radiotherapy and oncology, 189,

DOI: 10.1016/j.radonc.2023.109918

View all publications for Radiation Oncology clinical trials