Gastroenterology research

The four main areas of research for the Gastroenterology department are hepatology, endoscopy, inflammatory bowel disease and translational nutritional science.

Hepatology research spans the clinical management of viral hepatitis (particularly type C), epidemiology, hepatocellular cancer therapy, non-invasive staging and prognostic markers of liver disease, and management of portal hypertension.

Endoscopy focuses on improving the safety and quality of colonoscopic practice and of polypectomy, and colorectal neoplasia in cystic fibrosis.

Inflammatory bowel disease (IBD) research includes studies on optimising thiopurine therapy (with a focus on the use of allopurinol to improve efficacy and counteract side effects), the clinical utility of measurement of anti-TNF drug levels, and intestinal ultrasound.

The Translational Nutritional Science Group studies diet as a therapy in chronic intestinal disorders, including implementation of new approaches in the community.

Postgraduate students

14 PhD students
1 MD student

Our partners

Publications

The Role of Low-Dose Oral Methotrexate in Increasing Anti-TNF Drug Levels and Reducing Immunogenicity in IBD

Demase, Kathryn; Monitto, Cassandra; Little, Robert David; Sparrow, Miles Patrick

(2023), Journal of Clinical Medicine, 12(13), 4382

DOI: 10.3390/jcm12134382

A novel point-of-care test for cirrhosis based on dimeric to monomeric IgA ratio in blood: a pilot cohort study

Howell, Jessica; Van, Huy; Pham, Minh D.; Sawhney, Rohit; Li, Fan; Bhat, Purnima; Lubel, John; Kemp, William; Bloom, Steven; Majumdar, Avik; McCaughan, Geoff; Spelman, Timothy; Doyle, Joseph S.; Hellard, Margaret; Visvanathan, Kumar; Thompson, Alexander; Anderson, David

(2023), HEPATOLOGY COMMUNICATIONS, 7(4),

DOI: 10.1097/HC9.0000000000000106

Accuracy of ultrasound, bioelectrical impedance analysis and anthropometry as point‐of‐care measurements of skeletal muscle mass in patients with inflammatory bowel disease.

Nguyen, A. L., Burns, M., Herath, M., Lambell, K., Holt, D., Fitzpatrick, J., Milat, F., Ebeling, P. R., Gibson, P. R., & Moore, G. T

(2023), Alimentary Pharmacology & Therapeutics, 58(3), 309-21

DOI: 10.1111/apt.17607

View all publications for Gastroenterology research