Asthma: new treatment approach
Exciting research has led to new thinking about the causes and treatment of asthma, a condition that affects one in ten Australians.
The Alfred’s Head of Physiology Services, Professor Bruce Thompson, who is part of the investigator team of an NHMRC-funded National Clinical Centre of Research Excellence in Severe Asthma, will trial a new approach to the treatment of asthma.
Professor Thompson views asthma as an umbrella term for a condition that may be caused by different mechanisms yet result in the same dysfunction.
About 40 per cent of people with severe asthma do not have eosinophils in the sputum and do not respond well to inhaled corticosteroids, which is the mainstay of treatment. Along with a co-investigator in Sydney, Professor Thompson is working on targeting treatment to this so called steroid resistant asthma with a new approach that will involve patients inhaling a nebulised form of a commonly used antibiotic with anti-inflammatory properties.
Up to 60 participants will be involved in this four-year study at The Alfred. The study has huge potential to result in life-changing treatment for asthma sufferers who do not respond well to other existing treatments.